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Herzschrittmachertherapie & Elektrophysiologie.

Periodical
Cardiology
Physiology
Electrophysiology
Heart Diseases
Pacemaker
Artificial
Publisher:
Steinkopff Verlag,. Heidelberg : Springer Medizin
Frequency: Four no. a year, 1991-
Country: Germany
Language: ger
Author(s):
Deutsche Gesellschaft für Herz- und Kreislaufforschung.
Start Year:1990 -
Identifiers
ISSN:0938-7412 (Print)
1435-1544 (Electronic)
0938-7412 (Linking)
NLM ID:9425873
(DNLM):SR0069657(s)
(OCoLC):33751665
Coden:HEELFT
LCCN:sn 95050103
Classification:W1 HE988L
The ECG in cardiovascular-relevant animal models of electrophysiology.
Herzschrittmachertherapie & Elektrophysiologie    June 6, 2013   Volume 24, Issue 2 84-91 doi: 10.1007/s00399-013-0260-z
Kaese S, Frommeyer G, Verheule S, van Loon G, Gehrmann J, Breithardt G, Eckardt L.The most frequently used animal species in experimental cardiac electrophysiology are mice, rabbits, and dogs. Murine and human electrocardiograms (ECGs) show salient differences, including the occurrence of a pronounced J-wave and a less distinctive T-wave in the murine ECG. Mouse models can resemble human cardiac arrhythmias, although mice differ from human in cardiac electrophysiology. Thus, arrhythmia mechanisms in mice may differ from those in humans and should be transferred to the human situation with caution. Further relevant cardiovascular animal models are rabbits, dogs, and minipigs...