International wound journal.
Publisher:
Blackwell Pub.,
Frequency: Quarterly
Country: England
Language: English
Author(s):
Medicalhelplines.com, Inc.
Start Year:2004 -
ISSN:
1742-4801 (Print)
1742-481X (Electronic)
1742-4801 (Linking)
1742-481X (Electronic)
1742-4801 (Linking)
Impact Factor
3.1
2023
| NLM ID: | 101230907 |
| (OCoLC): | 56391945 |
| LCCN: | 2004243853 |
| Classification: | W1 IN928M |
The role of polyphosphates in the sequestration of matrix metalloproteinases. This study outlines the potential of a novel therapeutic dressing for the management of chronic wounds. The dressing incorporates polyphosphate, a non toxic compound with a number of beneficial characteristics in terms of wound healing, in a foam matrix. The aim of this study was to identify the potential of polyphosphate incorporated in the foam dressing to sequester the activity of matrix metalloproteinases (MMPs) and proteases derived from Pseudomonas aeruginosa. Methods used included gelatin zymography and milk-casein agar plate analysis. Results have shown that this dressing is effectivel...