Virchows Archiv : an international journal of pathology.
Publisher:
Springer International,
Frequency: Twelve no. a year
Country: Germany
Language: English
Start Year:1994 -
ISSN:
0945-6317 (Print)
1432-2307 (Electronic)
0945-6317 (Linking)
1432-2307 (Electronic)
0945-6317 (Linking)
Impact Factor
3.5
2022
| NLM ID: | 9423843 |
| (DNLM): | SR0079652(s) |
| (OCoLC): | 30055135 |
| Coden: | VARCEM |
| LCCN: | sn 94038299 |
| Classification: | W1 VI7635 |
Site of initiation of the plasma cell reaction in the rabbit lymph node. Ultrastructural evidence for two distinct antibody forming cell precursors. Two times sublethal total body-X-irradiation with weekly local thymus irradiation established a T-cell deprived experimental model in rabbits. Humoral immunity reactions in draining lymph nodes have been analyzed histologically and at the submicroscopical level after challenge with Salmonella Java vaccine, horse spleen ferritin, horse-gamma-globulin, a chemical sensitizer oxazolone (2 phenyl-4-ethoxymethylene-5-oxazolone) and after skin allografting respectively. The time sequence studies in these animals with an 'isolated B-cell system' are compared with similar experiments in normal non-irra...