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Archives of virology1995; 140(9); 1549-1555; doi: 10.1007/BF01322529

Bovine respiratory syncytial virus antibodies in non-bovine species.

Abstract: To study the role of non-bovine species in the epidemiology of bovine respiratory syncytial virus (RSV) infections, sera obtained from 9 non-bovine animal species and from humans were examined for bovine RSV specific antibodies. Sera were mainly from animals and humans which had been in contact with cattle. Forty sera of each species were tested in an RSV specific whole virus ELISA as well as in a peptide based ELISA, that was developed to measure antibodies specific for bovine RSV. Antibodies directed against RSV were detected in over 50% of sera obtained from sheep, goat, cattle and human beings, and anti-RSV activity was also found in some roe and dogs and one horse. Antibodies to bovine RSV were found in sera of all tested cattle, 11 (27.5%) goats and in some other individual animals: 3 horses, 2 roe, 1 cat and 1 dog. These results indicate that of the investigated species, besides cattle only goats might play a role in the epidemiology of bovine RSV.
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Publication Date: 1995-01-01 PubMed ID: 7487487DOI: 10.1007/BF01322529Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the presence of bovine respiratory syncytial virus (RSV) antibodies in non-bovine animals and humans who have come into contact with cattle. Antibodies against RSV were found in over 50% of sera from sheep, goats, cattle, and humans, suggesting that besides cattle, only goats might play a role in this virus’s epidemiology.

Research Methodology

  • The primary objective of this study was to understand the role of non-bovine species in the transmission and spread of the bovine respiratory syncytial virus (RSV).
  • Sera were obtained from nine different non-bovine animal species, as well as from humans, who had interacted with the cattle in some way.
  • The study used forty samples each from every species, testing them through an RSV-specific whole virus assay (ELISA), along with a peptide-based assay, designed particularly for detecting antibodies against bovine RSV.

Key Findings

  • The researchers found that over half of the sera obtained from sheep, goats, cattle, and humans contained the bovine RSV antibodies.
  • Additionally, anti-RSV activity was also reported in several roes and dogs, and one horse from the tested non-bovine animal species.
  • In all the cattle samples tested, the presence of RSV antibodies was confirmed. Also, 27.5% of the goat sera tested exhibited these antibodies.
  • For other individual animals, antibodies to bovine RSV were found in 3 horses, 2 roes, one cat, and one dog.

Conclusion

  • From the collected data, the study infers that besides cattle, only goats might significant contributors to the epidemiology of bovine RSV.
  • The research did not evidence a substantial contribution of other non-bovine species to the continued existence and spread of this virus, although some individual samples did test positive for RSV antibodies.

Cite This Article

APA
Van der Poel WH, Langedijk JP, Kramps JA, Middel WG, Brand A, Van Oirschot JT. (1995). Bovine respiratory syncytial virus antibodies in non-bovine species. Arch Virol, 140(9), 1549-1555. https://doi.org/10.1007/BF01322529

Publication

Archives of virology
ISSN: 0304-8608
NlmUniqueID: 7506870
Country: Austria
Language: English
Volume: 140
Issue: 9
Pages: 1549-1555

Researcher Affiliations

Van der Poel, W H
  • Department of Herd Health and Reproduction, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.
Langedijk, J P
    Kramps, J A
      Middel, W G
        Brand, A
          Van Oirschot, J T

            MeSH Terms

            • Amino Acid Sequence
            • Animals
            • Antibodies, Viral / analysis
            • Cats
            • Cattle
            • Dogs
            • Enzyme-Linked Immunosorbent Assay
            • Humans
            • Molecular Sequence Data
            • Peptides / chemistry
            • Peptides / immunology
            • Respiratory Syncytial Virus, Bovine / immunology

            References

            This article includes 15 references
            1. Duncan RB Jr, Potgieter LN. Antigenic diversity of respiratory syncytial viruses and its implication for immunoprophylaxis in ruminants.. Vet Microbiol 1993 Nov;37(3-4):319-41.
              pubmed: 8116189doi: 10.1016/0378-1135(93)90032-3google scholar: lookup
            2. Furze J, Wertz G, Lerch R, Taylor G. Antigenic heterogeneity of the attachment protein of bovine respiratory syncytial virus.. J Gen Virol 1994 Feb;75 ( Pt 2):363-70.
              pubmed: 8113757doi: 10.1099/0022-1317-75-2-363google scholar: lookup
            3. Orvell C, Norrby E, Mufson MA. Preparation and characterization of monoclonal antibodies directed against five structural components of human respiratory syncytial virus subgroup B.. J Gen Virol 1987 Dec;68 ( Pt 12):3125-35.
              pubmed: 2447224doi: 10.1099/0022-1317-68-12-3125google scholar: lookup
            4. Fields CG, Lloyd DH, Macdonald RL, Otteson KM, Noble RL. HBTU activation for automated Fmoc solid-phase peptide synthesis.. Pept Res 1991 Mar-Apr;4(2):95-101.
              pubmed: 1815783
            5. Alansari H, Potgieter LN. Nucleotide and predicted amino acid sequence analysis of the ovine respiratory syncytial virus non-structural 1C and 1B genes and the small hydrophobic protein gene.. J Gen Virol 1994 Feb;75 ( Pt 2):401-4.
              pubmed: 8113762doi: 10.1099/0022-1317-75-2-401google scholar: lookup
            6. Westenbrink F, Brinkhof JM, Straver PJ, Quak J, De Leeuw PW. Comparison of a newly developed enzyme-linked immunosorbent assay with complement fixation and neutralisation tests for serology of bovine respiratory syncytial virus infections.. Res Vet Sci 1985 May;38(3):334-40.
              pubmed: 4012035
            7. Akerlind-Stopner B, Utter G, Mufson MA, Orvell C, Lerner RA, Norrby E. A subgroup-specific antigenic site in the G protein of respiratory syncytial virus forms a disulfide-bonded loop.. J Virol 1990 Oct;64(10):5143-8.
              pubmed: 1697913doi: 10.1128/JVI.64.10.5143-5148.1990google scholar: lookup
            8. Mallipeddi SK, Samal SK. Analysis of the ovine respiratory syncytial virus (RSV) G glycoprotein gene defines a subgroup of ungulate RSV.. J Gen Virol 1993 Dec;74 ( Pt 12):2787-91.
              pubmed: 8277288doi: 10.1099/0022-1317-74-12-2787google scholar: lookup
            9. Bryson DG, McFerran JB, Ball HJ, Neill SD. Observations on outbreaks of respiratory disease in housed calves--(1) Epidemiological, clinical and microbiological findings.. Vet Rec 1978 Nov 25;103(22):485-9.
              pubmed: 219582doi: 10.1136/vr.103.22.485google scholar: lookup
            10. Verhoeff J, van Nieuwstadt AP. BRS virus, PI3 virus and BHV1 infections of young stock on self-contained dairy farms: epidemiological and clinical findings.. Vet Rec 1984 Mar 24;114(12):288-93.
              pubmed: 6326374doi: 10.1136/vr.114.12.288google scholar: lookup
            11. Van der Poel WH, Kramps JA, Middel WG, Van Oirschot JT, Brand A. Dynamics of bovine respiratory syncytial virus infections: a longitudinal epidemiological study in dairy herds.. Arch Virol 1993;133(3-4):309-21.
              pubmed: 8257292doi: 10.1007/BF01313771google scholar: lookup
            12. Alansari H, Potgieter LN. Nucleotide sequence analysis of the ovine respiratory syncytial virus G glycoprotein gene.. Virology 1993 Oct;196(2):873-7.
              pubmed: 8372453doi: 10.1006/viro.1993.1549google scholar: lookup
            13. Lerch RA, Anderson K, Wertz GW. Nucleotide sequence analysis and expression from recombinant vectors demonstrate that the attachment protein G of bovine respiratory syncytial virus is distinct from that of human respiratory syncytial virus.. J Virol 1990 Nov;64(11):5559-69.
              pubmed: 2214024doi: 10.1128/JVI.64.11.5559-5569.1990google scholar: lookup
            14. Lerch RA, Stott EJ, Wertz GW. Characterization of bovine respiratory syncytial virus proteins and mRNAs and generation of cDNA clones to the viral mRNAs.. J Virol 1989 Feb;63(2):833-40.
              pubmed: 2911122doi: 10.1128/JVI.63.2.833-840.1989google scholar: lookup
            15. Van der Poel WH, Brand A, Kramps JA, Van Oirschot JT. Respiratory syncytial virus infections in human beings and in cattle.. J Infect 1994 Sep;29(2):215-28.
              pubmed: 7806887doi: 10.1016/s0163-4453(94)90866-4google scholar: lookup

            Citations

            This article has been cited 4 times.
            1. Carlsson AM, Curry P, Elkin B, Russell D, Veitch A, Branigan M, Campbell M, Croft B, Cuyler C, Côté SD, Leclerc LM, Tryland M, Nymo IH, Kutz SJ. Multi-pathogen serological survey of migratory caribou herds: A snapshot in time. PLoS One 2019;14(7):e0219838.
              doi: 10.1371/journal.pone.0219838pubmed: 31365561google scholar: lookup
            2. Percopo CM, Dubovi EJ, Renshaw RW, Dyer KD, Domachowske JB, Rosenberg HF. Canine pneumovirus replicates in mouse lung tissue and elicits inflammatory pathology. Virology 2011 Jul 20;416(1-2):26-31.
              doi: 10.1016/j.virol.2011.04.010pubmed: 21600624google scholar: lookup
            3. Larsen LE. Bovine respiratory syncytial virus (BRSV): a review. Acta Vet Scand 2000;41(1):1-24.
              doi: 10.1186/BF03549652pubmed: 10920473google scholar: lookup
            4. Enkhbat M, Batzorig U, Dashdondog N, Trujillo-Vargas CM, Dambadarjaa D, Gray GC. The Highly Interrelated Morbidity Respiratory Viruses Cause Among Humans and Animals in Mongolia. Viruses 2025 Nov 28;17(12).
              doi: 10.3390/v17121557pubmed: 41472228google scholar: lookup
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