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Home / Equine Research Bank / Can Vet J / Cartilage healing: A review with emphasis on the equine mode...
The Canadian veterinary journal = La revue veterinaire canadienne1990; 31(8); 565-572;

Cartilage healing: A review with emphasis on the equine model.

Abstract: Articular cartilage is a remarkably resilient tissue capable of withstanding considerable stress and repeated loading. Since this tissue has no blood vessels, nerve elements, or lymphatics, it is not surprising that it has a limited capacity for repair when damaged. In the horse, cartilage damage occurs as an occupational hazard. Furthermore, developmental defects such as osteochondrosis can lead to osteochondritis dissecans. Resultant cartilage flaps, fissures, and poorly organized subchondral bone produce disruption of joint surfaces.Veterinarians are often called upon to intervene when damaged cartilage has healed incompletely. Basic understanding of the physiology and repair mechanisms of cartilage is paramount to successfully managing such injuries. This literature review gives a brief overview of recently published clinical and experimental studies on the healing of cartilage. The discussion centers on the equine model.
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Publication Date: 1990-08-01 PubMed ID: 17423644PubMed Central: PMC1480835
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article provides an overview of the challenges and potential solutions in healing cartilage damage, particularly in horses. It explores the physiology of cartilage and the mechanisms that contribute to its repair.

Overview of Cartilage and its Repair Mechanisms

  • The article starts by highlighting the unique characteristics of articular cartilage. This type of tissue is highly resilient and capable of withstanding significant stress. However, it does not have blood vessels, nerve elements or lymphatics, which restricts its capacity for self-repair when damaged.
  • It then discusses the causes of cartilage damage. For horses, this often happens as an occupational hazard. Furthermore, developmental defects, such as osteochondrosis, can progress into a condition called osteochondritis dissecans. This leads to issues like cartilage flaps, fissures and poorly organized subchondral bone, all of which disrupt the smoothness of joint surfaces.
  • The main focus here is how important it is for veterinarians to intervene when there is incomplete healing of damaged cartilage. A thorough understanding of cartilage physiology and repair mechanisms is vital to manage these injuries effectively.

Evaluation and Discussion on Recent Studies on Cartilage Repair

  • After presenting the need for advanced understanding on cartilage healing, the article shifts to a review of clinical and experimental studies lately published on this topic.
  • These studies presumably cover a variety of methods and approaches to cartilage healing, providing a comprehensive look at current research in the field. However, the abstract does not provide specific details about the studies reviewed.
  • The discussion in this article is firmly based on the equine model. This focus on horses is significant, as horses frequently suffer from cartilage injuries due to their active lifestyle and physical demands. The findings may offer important insights for equine vets and possibly lead to breakthroughs in managing such injuries among horses.

Cite This Article

APA
Desjardins MR, Hurtig MB. (1990). Cartilage healing: A review with emphasis on the equine model. Can Vet J, 31(8), 565-572.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 31
Issue: 8
Pages: 565-572

Researcher Affiliations

Desjardins, M R
    Hurtig, M B

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      Citations

      This article has been cited 4 times.
      1. Hill EW, Stoffel MA, McGivney BA, MacHugh DE, Pemberton JM. Inbreeding depression and the probability of racing in the Thoroughbred horse. Proc Biol Sci 2022 Jun 29;289(1977):20220487.
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        doi: 10.1186/s13287-019-1499-zpubmed: 31847882google scholar: lookup
      4. White JL, Walker NJ, Hu JC, Borjesson DL, Athanasiou KA. A Comparison of Bone Marrow and Cord Blood Mesenchymal Stem Cells for Cartilage Self-Assembly. Tissue Eng Part A 2018 Aug;24(15-16):1262-1272.
        doi: 10.1089/ten.TEA.2017.0424pubmed: 29478385google scholar: lookup
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