Equine veterinary journal. Supplement1990; (10); 8-11; doi: 10.1111/j.2042-3306.1990.tb04701.x

Conjunctival and nasal amyloidosis in a horse.

Mould, JR
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Munroe, GA
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Eckersall, PD
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Conner, JG
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McNeil, PE

Abstract: AMYLOID is the extra-cellular deposition of hyaline proteinaceous material of various types, with the characteristic of green birefringence of Congo Red stained sections under polarised light. It is of wide veterinary importance (Jako 1971; Woo and Gorman 1989). In the horse, it occurs as a complication of chronic inflammation or antigenic stimulation (Jakob 1971; Husebekk et al 1986; van Andel, Gruys, Kroneman and Veerkamp 1988; Vanhooser, Reinemeyer and Held 1988) and as an unusual cause of tumour-like masses in the rostral nasal cavity (Shaw, Gunson and Evans 1987; van Andel et al 1988). Rarely, amyloid has been reported as a cause of tumour-like nodules in the conjunctiva of the horse with a clinical appearance comparable to the same condition in man (Hjarre and Nordlund 1939; Hjarre 1942; Smith and Zimmerman 1966; Saunders and Rubin 1975). This report describes a case of combined conjunctival and nasal amyloidosis in a horse.

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Publication Date: 1990-09-01 PubMed ID: 9079107DOI: 10.1111/j.2042-3306.1990.tb04701.xGoogle Scholar: Lookup

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Amyloidosis

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The research article discusses a rare case of a horse with both conjunctival and nasal amyloidosis, conditions that result from the cellular deposition of proteinaceous material, which is typically a complication of chronic inflammation or antigenic stimulation and sometimes presents as tumor-like growths.

Understanding Amyloidosis

Amyloidosis is a condition characterized by the extracellular deposition of a type of protein, known as amyloid, which has the characteristic property of showing green birefringence when stained with Congo Red and examined under polarized light.
This condition is relevant in veterinary medicine, implying its significance in the health and well-being of animals.

Amyloidosis in Horses

In the case of horses, amyloidosis is usually seen as a result of chronic inflammation or antigenic stimulation. The term ‘antigenic stimulation’ refers to the introduction of antigens into the body of the horse, which may lead to an immune response and the subsequent inflammation leading to amyloid deposition.
Sometimes, amyloidosis in horses manifests as tumor-like structures in the rostral nasal cavity. The rostral nasal cavity is the front part of the horse’s nose. Thus, this uncontrolled growth can easily be detected and diagnosed due to its visibility.