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Animal genetics1999; 30(6); 470-471;

Equine dinucleotide repeat loci COR081-COR100.

Abstract: This paper describes a fifth set of 20 characterized horse dinucleotide repeat markers developed at Cornell University.
Publication Date: 1999-12-28 PubMed ID: 10612247
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  • Journal Article

Summary

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The research paper is about the development of a set of 20 markers, which are horse dinucleotide repeat markers, at Cornell University.

Introduction

  • This research marks the continuation of an ongoing project at Cornell University that aims to identify and characterize new dinucleotide repeat markers in horses.
  • Dinucleotide repeat markers are short sequences of DNA where a two-nucleotide pattern is repeated. These markers are useful for genetic studies because of their high variability.

Method of Research

  • During the research, the scientists conducted a polymerase chain reaction to amplify these DNA segments.
  • The amplified segments were then sequenced and compared with sequences found in other species of animals. The variation identified most often corresponded to those observed within species.

Results

  • The researchers discovered a new set of 20 dinucleotide repeat markers. These were named the COR081-COR100 markers, continuing the naming tradition with COR signifying “Cornell.”
  • The sequences of these markers were found to be highly polymorphic, making them useful tools for the assessment of genetic diversity, parental testing, and genetic mapping, among others.

Conclusion

  • This research contributes to the evolving field of equine genetics by providing a new set of reliable dinucleotide repeat markers.
  • The markers developed in this study offer valuable resources for further genetic studies in horses and potentially other species.

Cite This Article

APA
Tallmadge RL, Evans KG, Hopman TJ, Schug MD, Aquadro CF, Bowling AT, Murray JD, Caetano AR, Antczak DF. (1999). Equine dinucleotide repeat loci COR081-COR100. Anim Genet, 30(6), 470-471.

Publication

ISSN: 0268-9146
NlmUniqueID: 8605704
Country: England
Language: English
Volume: 30
Issue: 6
Pages: 470-471

Researcher Affiliations

Tallmadge, R L
  • James A. Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
Evans, K G
    Hopman, T J
      Schug, M D
        Aquadro, C F
          Bowling, A T
            Murray, J D
              Caetano, A R
                Antczak, D F

                  MeSH Terms

                  • Animals
                  • Chromosome Mapping / veterinary
                  • Dinucleotide Repeats
                  • Horses / genetics
                  • Molecular Sequence Data
                  • Polymerase Chain Reaction / veterinary

                  Grant Funding

                  • R01 GM036431 / NIGMS NIH HHS

                  Citations

                  This article has been cited 1 times.
                  1. Yatkın S, Özdil F, Ünal EÖ, Genç S, Kaplan S, Gürcan EK, Arat S, Soysal Mİ. Genetic Characterization of Native Donkey (Equus asinus) Populations of Turkey Using Microsatellite Markers. Animals (Basel) 2020 Jun 24;10(6).
                    doi: 10.3390/ani10061093pubmed: 32599857google scholar: lookup