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The veterinary quarterly2001; 23(2); 92-95; doi: 10.1080/01652176.2001.9695090

Haematological and blood biochemical characteristics of Dutch warmblood foals managed under three different rearing conditions from birth to 5 months of age.

Abstract: Reference values for haematological and blood biochemical variables may vary per breed and are influenced by age and, to a certain extent, by rearing conditions. To investigate the influence of age and rearing conditions, these variables were measured in Dutch Warmblood foals from birth to 5 months of age. The foals were divided into three groups with different exercise regimens: 14 foals got boxrest with no exercise; 14 foals were kept in comparable boxes, but received daily exercise; and 15 foals were maintained on pasture with free exercise. Blood samples were collected each month and 36 haematological and biochemical variables were measured. The influence of age and rearing conditions was statistically evaluated. Significant age effects were found for all variables with the exception of band-shaped leucocytes, eosinophilic leucocytes, basophilic leucocytes, monocytes, platelets, pCO2, and sodium, potassium, calcium, magnesium, creatinine and creatine phosphokinase levels. Rearing conditions appeared to influence the haemoglobin, packed cell volume, pH, base excess, bicarbonate, chloride, urea, and alkaline phosphatase values. Most age-related differences can be explained by growth and differentiation-related processes that are specific for young animals. Differences due to the different rearing conditions can partly be explained by the higher metabolism and greater maturation of tissues in foals maintained on pasture with free exercise. Some other differences were minor and were probably of no clinical relevance. The conclusion is that haematological and blood biochemical variables in the Dutch Warmblood foal mainly depend on age, thus warranting the use of specific age-related reference values for foals of this breed.
Publication Date: 2001-05-22 PubMed ID: 11361107DOI: 10.1080/01652176.2001.9695090Google Scholar: Lookup
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  • Journal Article

Summary

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This research looks into the haematological and blood biochemical characteristics of Dutch Warmblood foals from birth to five months of age, comparing how three different rearing conditions affect these variables. The findings indicate that the foal’s age significantly influences these factors, and specific age-related reference values are necessary for foals of this particular breed.

Study Details

  • The study involved Dutch Warmblood foals split into three groups based on their rearing conditions. One group consisted of 14 foals kept in boxrest with no exercise, the second group also had 14 foals kept in similar boxes but received daily exercise, and the final group had 15 foals raised in a pasture with free exercise.
  • The researchers took blood samples from the foals every month and measured 36 haematological and biochemical variables. The data was statistically analyzed to determine the influence of age and the rearing conditions on these variables.

Findings

  • Significant effects of age were found on all variables except for certain forms of leucocytes (white blood cells), platelets, and levels of several elements and substances, including sodium, potassium, calcium, magnesium, creatinine, and creatine phosphokinase.
  • The rearing conditions had a notable influence on factors like hemoglobin, packed cell volume, pH, base excess, bicarbonate, chloride, urea, and alkaline phosphatase values.
  • Most differences detected due to age are attributable to growth and specific processes of differentiation that occur in young animals.
  • Rearing-related differences can be partly linked to a higher metabolism and more mature tissues in foals that had free access to exercise in a pasture. Some of these distinctions, however, were minor and likely not clinically significant.

Conclusion

  • The conclusions drawn from the research state that the age of Dutch Warmblood foals largely influences their haematological and blood biochemical variables. As such, for a better understanding of these aspects in foals of this breed, it is recommended to use specific age-related reference values.

Cite This Article

APA
Brommer H, Sloet van Oldruitenborgh-Oosterbaan MM, Kessels B. (2001). Haematological and blood biochemical characteristics of Dutch warmblood foals managed under three different rearing conditions from birth to 5 months of age. Vet Q, 23(2), 92-95. https://doi.org/10.1080/01652176.2001.9695090

Publication

ISSN: 0165-2176
NlmUniqueID: 7909485
Country: England
Language: English
Volume: 23
Issue: 2
Pages: 92-95

Researcher Affiliations

Brommer, H
  • Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, The Netherlands. H.Brommer@vet.uu.nl
Sloet van Oldruitenborgh-Oosterbaan, M M
    Kessels, B

      MeSH Terms

      • Aging / blood
      • Animals
      • Animals, Newborn / blood
      • Blood Chemical Analysis / veterinary
      • Female
      • Hematologic Tests / veterinary
      • Horses / blood
      • Male
      • Physical Conditioning, Animal / physiology
      • Random Allocation
      • Reference Values

      Citations

      This article has been cited 5 times.
      1. Olivo G, Lucas TM, Borges AS, Silva RO, Lobato FC, Siqueira AK, da Silva Leite D, Brandão PE, Gregori F, de Oliveira-Filho JP, Takai S, Ribeiro MG. Enteric Pathogens and Coinfections in Foals with and without Diarrhea. Biomed Res Int 2016;2016:1512690.
        doi: 10.1155/2016/1512690pubmed: 28116290google scholar: lookup
      2. Zakari FO, Ayo JO, Rekwot PI, Kawu MU. Effect of age, sex, physical activity and meteorological factors on haematological parameters of donkeys (Equus asinus). Comp Clin Path 2016;25(6):1265-1272.
        doi: 10.1007/s00580-014-2026-3pubmed: 27818622google scholar: lookup
      3. Zakari FO, Ayo JO, Rekwot PI, Kawu MU. Effects of age and season on haematological parameters of donkeys during the rainy and cold-dry seasons. Int J Biometeorol 2015 Dec;59(12):1813-24.
        doi: 10.1007/s00484-015-0989-7pubmed: 25860334google scholar: lookup
      4. Suska M, Skotnicka E. Changes in Adenylate Nucleotides Concentration and Na, K-ATPase Activities in Erythrocytes of Horses in Function of Breed and Sex. Vet Med Int 2010;2010:987309.
        doi: 10.4061/2010/987309pubmed: 20445796google scholar: lookup
      5. Wong DM, Vo DT, Alcott CJ, Stewart AJ, Peterson AD, Sponseller BA, Hsu WH. Adrenocorticotropic hormone stimulation tests in healthy foals from birth to 12 weeks of age. Can J Vet Res 2009 Jan;73(1):65-72.
        pubmed: 19337398