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Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B1983; 30(3); 232-236; doi: 10.1111/j.1439-0450.1983.tb01838.x

Laboratory investigations on equine influenza during the outbreak in Poland in 1980.

Abstract: Summary The outbreak of equine influenza in Poland in 1980 was caused by an equine influenza virus antigenically related to the strain A/equine/Miami/63/Heq2, Neq2. This was confirmed by isolation of six strains of influenza virus from horses suffering from the acute form of the disease. About 45 % and 69 % of positive results were obtained in the HI test performed with sera taken from convalescent and affected animals, respectively. A relatively high level of antibodies against newly isolated equine influenza virus strains was found in 50 % of serum samples taken from the grooms. A relatively low level of antibodies was found in sera tested by the ASO test. Zusammenfassung Laboruntersuchungen über die Pferdeinfluenza während des Ausbruchs in Polen im Jahre 1980 Der Ausbruch von Pferdeinfluenza in Polen im Jahre 1980 wurde durch ein equines Influenzavirus verursacht, das zum Stamm A/equine/Miami/63/Heq2, Neq2 antigenverwandt ist. Dies wurde bestätigt durch die Isolierung von sechs Influenzavirusstämmen von Pferden, die an der akuten Form der Krankheit litten. Im HI-Test reagierten 45 % der Seren von Rekonvaleszenten und 69 % der Seren erkrankter Tiere positiv. Relativ hohe Antikörpertiter gegen die neu isolierten equinen Influenzavirusstämme wurden in 50 % der Serumproben von Pferdepflegern gefunden. Relativ niedrige Antikörpertiter wurden in den Seren gefunden, die mit dem ASO-Test untersucht wurden. Résumé Recherches en laboratoire sur l'Influenza équine durant l'épizootie en 1980 en Pologne L'épizootie d'Influenza équine de 1980 en Pologne fut provoquée par un virus Influenza équin apparenté antigéniquement à la souche A/equine/Miami/63/Heq2, Neq2. Cela a été confirmé par l'isolement de 6 souches de virus Influenza chez des chevaux atteints par la maladie sous sa forme aiguë. 45 % des sérums d'animaux convalescents et 69 % des sérums d'animaux malades ont réagi positivement au test d'inhibition de l'hémagglutination. 50 % des échantillons de sérums des palefreniers ont présenté des titres d'anticorps relativement élevés vis-à-vis des nouvelles souches isolées de virus Influenza équin. Des titres d'anticorps relativement bas ont été trouvés dans les sérums examinés avec le test ASO. Resumen Estudios de laboratorio sobre la influenza equina durante el brote que hubo en Polonia en 1980 El brote de influenza equina que afectó a Polonia en el año 1980 fué originado por un virus influenza equina que tiene cierto parentesco antigénico con la estirpe A/equine/Miami/63/Heq2, Neq2. Esto se confirmó mediante el aislamiento de seis estirpes de virus influenza de caballos, los cuales padecían de la forma aguda de la enfermedad. En la prueba de HI reaccionaban positivamente el 45 % de los sueros de convalecientes y el 69 % de los sueros sanguíneos de animales enfermos. Se hallaron títulos de anticuerpos relativamente elevados frente a las estirpes nuevas de virus influenza equina aisladas en el 50 % de las muestras séricas del personal encargado de los caballos. Títulos de anticuerpos relativamente bajos se encontraron en los sueros que fueron analizados con la prueba ASO.
Publication Date: 1983-04-01 PubMed ID: 6306960DOI: 10.1111/j.1439-0450.1983.tb01838.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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The research paper studies an outbreak of equine influenza in Poland in 1980, its cause, and how it affected both horses and their caregivers.

Overview of the Outbreak and Virus Strain

  • The researchers discovered that the equine influenza outbreak in Poland in 1980 was caused by an influenza virus strain similar to A/equine/Miami/63/Heq2, Neq2. To confirm this, they successfully isolated six of these virus strains from horses that were suffering from the acute form of the disease.

Results from the HI Test

  • When the scientists conducted a Hemagglutination Inhibition (HI) test, they discovered that 45% of the tested sera from recovering animals demonstrated positive results. This means these samples were reactive or contained antibodies against the said strain of equine influenza virus.
  • Interesting, a higher percentage (69%) of positive results were obtained from the sera of diseased animals, indicating that most of the affected horses produced a measurable immune response to the virus.

Antibody Levels in Humans

  • The researchers also tested the human grooms, the persons in regular close contact with the horses. They found that about 50% of these individuals had a relatively high level of antibodies against the newly isolated equine influenza virus strains. This suggested that these humans had been exposed to the virus and their immune systems had responded by producing antibodies to fight it off.

Results from the ASO Test

  • The researchers conducted an Antistreptolysin O (ASO) test on the sera. This test is often used to check for past infections by group A streptococcus bacteria, which might be unrelated to the influenza virus. The results revealed a relatively low level of antibodies, likely indicating this test wasn’t as effective in detecting antibodies for the equine influenza virus or the individuals tested didn’t have a recent streptococcus infection.

Cite This Article

APA
Weremowicz S, Parzych R, Malicki K. (1983). Laboratory investigations on equine influenza during the outbreak in Poland in 1980. Zentralbl Veterinarmed B, 30(3), 232-236. https://doi.org/10.1111/j.1439-0450.1983.tb01838.x

Publication

ISSN: 0514-7166
NlmUniqueID: 0331325
Country: Germany
Language: English
Volume: 30
Issue: 3
Pages: 232-236

Researcher Affiliations

Weremowicz, S
    Parzych, R
      Malicki, K

        MeSH Terms

        • Animals
        • Antibodies, Viral / analysis
        • Bacteria / isolation & purification
        • Disease Outbreaks / veterinary
        • Horse Diseases / immunology
        • Horse Diseases / microbiology
        • Horses
        • Influenza A virus / immunology
        • Influenza A virus / isolation & purification
        • Orthomyxoviridae Infections / immunology
        • Orthomyxoviridae Infections / microbiology
        • Orthomyxoviridae Infections / veterinary
        • Poland

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