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Modern veterinary practice1984; 65(8); 589-595;

Practical toxicologic diagnosis.

Abstract: Strychnine toxicosis is characterized by inducible tetanic seizures and metaldehyde poisoning by fine fasciculations progressing to generalized tremors and seizures. Intoxication with 1080 causes seizures, random running movements, vomiting, defecation, urination, acidosis and hyperglycemia. Intoxication with rodenticides causing coagulopathy is characterized by hemorrhage into body cavities but not necessarily external hemorrhage. Anticholinesterase insecticides cause salivation, urination and defecation, while chlorinated hydrocarbon insecticides cause CNS disturbances. Ethylene glycol intoxication results in ataxia, depression, coma, vomiting and tachypnea, followed by acute renal failure. Urea poisoning causes bloat and CNS signs in cattle. Monensin intoxication in horses lasts several days and causes stiffness, colic, uneasiness and recumbency. Salt poisoning results in depression, seizures and hypernatremia. Lead poisoning is associated with central and peripheral nervous system signs, as well as increased numbers of nucleated RBC and basophilic stippling of RBC. Arsenic poisoning results in GI pain, diarrhea, weakness and death. Copper toxicosis in sheep is manifested by hemolytic anemia, hemoglobinemia and hemoglobinuria. Plants that may intoxicate domestic animals include sorghum, greasewood, halogeton, water hemlock, Japanese yew, larkspur, lupine, milk-weed, philodendron, oleander, castor bean and precatory bean.
Publication Date: 1984-08-01 PubMed ID: 6493203
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  • Journal Article

Summary

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The research article provides an in-depth exploration of various aspects of toxicosis in animals. It details common symptoms associated with specific poisonings, such as those caused by strychnine, rodenticides, ethylene glycol, urea, and various poisonous plants, among others.

Types of Animal Poisoning

  • The study breaks down varied types of toxicosis in the animal population, starting off with strychnine toxicosis which leads to tetanic seizures.
  • Metaldehyde poisoning displays fine fasciculations graduating to generalized tremors and seizures.
  • 1080 intoxication is exhibited through seizures, random running movements, and several uncommon symptoms such as vomiting, defecation, urination, acidosis, and hyperglycemia.
  • Rodenticides cause coagulopathy which is characterized by internal hemorrhage.
  • Anticholinesterase insecticides bring about salivation, urination, defecation, while chlorinated hydrocarbon insecticides induce disturbances in the central nervous system.

Poisoning by Substances and Compounds

  • The study discusses ethylene glycol intoxication which results in ataxia, depression, coma, vomiting, shortness of breath, and eventually leads to acute renal failure.
  • Urea poisoning causes bloat and CNS signs in cattle, while Monensin intoxication in horses lasts several days and causes stiffness, colic, uneasiness, laying down, and refusal or inability to stand.
  • Salt poisoning results in depression, seizures, and high sodium levels in the blood.

Poisoning by Heavy Metals

  • The report further explores symptoms of Lead poisoning which include signs of central and peripheral nervous system disturbances, elevated number of nucleated Red Blood Cells (RBC) and distinctive basophilic stippling of RBCs.
  • Arsenic poisoning causes gastrointestinal pain, diarrhea, weakness, and may result in death.
  • Copper toxicosis specifically in sheep is manifested through hemolytic anemia, hemoglobinemia, and hemoglobinuria.

Poisoning by Plant Life

  • The research also identifies a range of plants that may cause intoxication in animals which include sorghum, greasewood, halogeton, water hemlock, Japanese yew, larkspur, lupine, milk-weed, philodendron, oleander, castor bean, and precatory bean.

Cite This Article

APA
Mount ME, Feldman BF. (1984). Practical toxicologic diagnosis. Mod Vet Pract, 65(8), 589-595.

Publication

ISSN: 0362-8140
NlmUniqueID: 7802904
Country: United States
Language: English
Volume: 65
Issue: 8
Pages: 589-595

Researcher Affiliations

Mount, M E
    Feldman, B F

      MeSH Terms

      • Animals
      • Blood Coagulation Disorders / chemically induced
      • Blood Coagulation Disorders / veterinary
      • Central Nervous System Diseases / chemically induced
      • Central Nervous System Diseases / veterinary
      • Ethylene Glycols / poisoning
      • Food Additives / poisoning
      • Insecticides / poisoning
      • Metals / poisoning
      • Plants, Toxic
      • Poisoning / diagnosis
      • Poisoning / veterinary
      • Rodenticides / poisoning

      Citations

      This article has been cited 2 times.
      1. Tharwat M. Clinical, ultrasonographic, and postmortem findings in sheep and goats with urinary tract disorders.. Vet World 2021 Jul;14(7):1879-1887.
      2. Ollivett TL, McGuirk SM. Salt poisoning as a cause of morbidity and mortality in neonatal dairy calves.. J Vet Intern Med 2013 May-Jun;27(3):592-5.
        doi: 10.1111/jvim.12078pubmed: 23551171google scholar: lookup