FREE SHIPPING over $40
OVER 10000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Equine veterinary journal2023; doi: 10.1111/evj.14031

Resolution of two cases of ovarian abscesses in mares subjected to ovum pick up.

Abstract: Currently, for in vitro embryo production in live mares, immature oocytes are retrieved by transvaginal follicular aspiration or ovum pick up (OPU). Occasionally, ovarian abscesses have been described after OPU, but no current consensus exists on how to treat this condition. Objective: To describe diagnosis and successful treatment of ovarian abscesses in two mares subjected to OPU. Methods: Case report. Methods: Case records were reviewed and summarised. Results: In the first case, a pony mare showed tachypnoea, tachycardia, high temperature, leukocytosis, left hindlimb lameness and slight increase in concentration of serum amyloid A. Ultrasonography revealed an increase in the size of the left ovary and two well defined structures suggestive of ovarian abscess. A left ovariectomy by standing laparoscopy was the treatment of choice: the diagnosis was confirmed, and bacterial culture produced heavy growth of Streptococcus equi Zooepidemicus. In the second mare, an abnormal structure was observed in the left ovary in a routine transrectal ultrasonographic exam in the absence of any clinical signs or abnormal blood parameters. A medical approach was chosen and a sample of the purulent material was aspirated with a transvaginal ultrasound-guided approach. The sample yielded a heavy growth of Streptococcus equi Zooepidemicus after culture. Treatment was initiated with rifampicin and trimethoprim-sulfadiazine based on the antibiogram results and the abscess completely resolved after 40 days. Conclusions: Limited to two cases. Conclusions: Ovarian abscesses in mares can be successfully treated both surgically and medically.
© 2023 The Authors. Equine Veterinary Journal published by John Wiley & Sons Ltd on behalf of EVJ Ltd.
Get Full Text
Publication Date: 2023-12-11 PubMed ID: 38083902DOI: 10.1111/evj.14031Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article describes two cases of successful treatment of ovarian abscesses in mares that underwent Ovum Pickup (OPU), a process of retrieving immature oocytes for in vitro embryo production, emphasizing that such abscesses can be treated both surgically and medically.

Summary of the Research Method

  • The study uses a case report method, providing a comprehensive review and analysis of two cases where mares developed ovarian abscesses post OPU.

Details of the Cases

  • In the first case, the mare exhibited symptoms such as tachypnoea (rapid breathing), tachycardia (rapid heart rate), high temperature, leukocytosis (increase in the number of white blood cells), left hindlimb lameness, and a slight increase in the concentration of serum amyloid A, a marker of inflammation. An ultrasonographic examination showed an enlarged left ovary with two distinct structures suggestive of an ovarian abscess.
  • The chosen treatment for the first mare was a standing laparoscopy ovariectomy, a surgical removal of the left ovary. The diagnosis was then confirmed, and a bacterial culture showed a significant presence of Streptococcus equi Zooepidemicus, a common bacterial pathogen in horses.
  • The second mare lacked any clinical signs of an abscess or abnormal blood parameters, but a routine transrectal ultrasonographic examination revealed an abnormal structure in the left ovary.
  • This case suggested a medical approach where a sample of the purulent material from the abscess was aspirated using a transvaginal ultrasound-guided method. Like the first case, the sample culture revealed a significant presence of Streptococcus equi Zooepidemicus.
  • Based on antibiogram results, the treatment regimen for the second mare included rifampicin and trimethoprim-sulfadiazine. After 40 days of this treatment, the abscess completely resolved.

Key Findings and Conclusion

  • The study emphasizes the successful treatment of ovarian abscesses in mares, stating that it is possible to go both the surgical and medical routes depending on the severity and symptoms presented by the mare.
  • However, the reliability of the study’s conclusion is limited due to the availability of data from just two distinct cases. Further investigation is required to solidify the findings.

Cite This Article

APA
Fernández-Hernández P, Valero-González M, Fuentes-Romero B, Iglesias-García M, Ezquerra-Calvo LJ, Martín-Cuervo M, Macías-García B. (2023). Resolution of two cases of ovarian abscesses in mares subjected to ovum pick up. Equine Vet J. https://doi.org/10.1111/evj.14031

Publication

Equine veterinary journal
ISSN: 2042-3306
NlmUniqueID: 0173320
Country: United States
Language: English

Researcher Affiliations

Fernández-Hernández, Pablo
  • Departamento de Medicina Animal, Facultad de Veterinaria, Grupo de Investigación Medicina Interna Veterinaria (MINVET), Universidad de Extremadura, Cáceres, Spain.
Valero-González, Marta
  • Hospital Clínico Veterinario, Universidad de Extremadura, Cáceres, Spain.
Fuentes-Romero, Beatriz
  • Hospital Clínico Veterinario, Universidad de Extremadura, Cáceres, Spain.
Iglesias-García, Manuel
  • Hospital Clínico Veterinario, Universidad de Extremadura, Cáceres, Spain.
Ezquerra-Calvo, Luis Javier
  • Departamento de Medicina Animal, Grupo MECIAN, Universidad de Extremadura, Cáceres, Spain.
Martín-Cuervo, Maria
  • Departamento de Medicina Animal, Grupo MECIAN, Universidad de Extremadura, Cáceres, Spain.
Macías-García, Beatriz
  • Departamento de Medicina Animal, Facultad de Veterinaria, Grupo de Investigación Medicina Interna Veterinaria (MINVET), Universidad de Extremadura, Cáceres, Spain.

Grant Funding

  • IB20005 / Consejeru00eda de Educaciu00f3n y Empleo, Junta de Extremadura
  • PID2020-112723RBI00 / ERDF A Way of Making Europe
  • MCIN/AEI/10.13039/501100011033

References

This article includes 26 references
  1. Squires E. Current reproductive technologies impacting equine embryo production.. J Equine Vet 2020;89:102981.
    doi: 10.1016/j.jevs.2020.102981google scholar: lookup
  2. Brück I, Raun K, Synnestvedt B, Greve T. Follicle aspiration in the mare using a transvaginal ultrasound-guided technique.. Equine Vet J 1992;24:58-59.
    doi: 10.1111/j.2042-3306.1992.tb02780.xgoogle scholar: lookup
  3. Galli C, Duchi R, Colleoni S, Lagutina I, Lazzari G. Ovum pick up, intracytoplasmic sperm injection and somatic cell nuclear transfer in cattle, buffalo and horses: from the research laboratory to clinical practice.. Theriogenology 2014;81:138-151.
    doi: 10.1016/j.theriogenology.2013.09.008google scholar: lookup
  4. Velez IC, Arnold C, Jacobson CC, Norris JD, Choi YH, Edwards JF. Effects of repeated transvaginal aspiration of immature follicles on mare health and ovarian status: effect of transvaginal aspiration on health.. Equine Vet J 2012;44:78-83.
    doi: 10.1111/j.2042-3306.2012.00606.xgoogle scholar: lookup
  5. Vanderwall DK, Woods GL. Severe internal hemorrhage resulting from transvaginal ultrasound-guided follicle aspiration in a mare.. J Equine Vet 2002;22:84-86.
    doi: 10.1016/s0737-0806(02)70094-4google scholar: lookup
  6. Stout TAE. Clinical application of in vitro embryo production in the horse.. J Equine Vet 2020;89:103011.
    doi: 10.1016/j.jevs.2020.103011google scholar: lookup
  7. Cuervo-Arango J, Claes AN, Stout TA. A retrospective comparison of the efficiency of different assisted reproductive techniques in the horse, emphasizing the impact of maternal age.. Theriogenology 2019;132:36-44.
    doi: 10.1016/j.theriogenology.2019.04.010google scholar: lookup
  8. Hinrichs K. Assisted reproductive techniques in mares.. Reprod Domest Anim Zuchthyg 2018;53(Suppl 2):4-13.
    doi: 10.1111/rda.13259google scholar: lookup
  9. Bøgh IB, Brink P, Jensen HE, Lehn-Jensen H, Greve T. Ovarian function and morphology in the mare after multiple follicular punctures.. Equine Vet J 2010;35:575-579.
    doi: 10.2746/042516403775467243google scholar: lookup
  10. Ramirez S, Sedrish SA, Paccamonti DL, French DD. Ultrasound as an aid for diagnosis of ovarian abscesses in two mares.. Vet Radiol Ultrasound 1999;40:165-168.
    doi: 10.1111/j.1740-8261.1999.tb01903.xgoogle scholar: lookup
  11. Rosen M, Breitkopf D, Waud K. Tubo-ovarian abscess management options for women who desire fertility.. Obstet Gynecol Surv 2009;64:681-689.
    doi: 10.1097/ogx.0b013e3181b8b0d6google scholar: lookup
  12. Carnevale EM. Advances in collection, transport and maturation of equine oocytes for assisted reproductive techniques.. Vet Clin North Am Equine Pract 2016;32:379-399.
    doi: 10.1016/j.cveq.2016.07.002google scholar: lookup
  13. Röcken M, Mosel G, Seyrek-Intas K, Seyrek-Intas D, Litzke F, Verver J. Unilateral and bilateral laparoscopic ovariectomy in 157 mares: a retrospective multicenter study.. Vet Surg 2011;40:1009-1014.
    doi: 10.1111/j.1532-950x.2011.00884.xgoogle scholar: lookup
  14. Woodie BJ. Uterus and ovaries.. In: Auer JA, editor. Equine surgery. 5th ed. St. Louis, MO: Elsevier; 2018. p. 1083-1087.
  15. Gjelland K, Ekerhovd E, Granberg S. Transvaginal ultrasound-guided aspiration for treatment of tubo-ovarian abscess: a study of 302 cases.. Am J Obstet Gynecol 2005;193:1323-1330.
    doi: 10.1016/j.ajog.2005.06.019google scholar: lookup
  16. Kairys N, Roepke C. Tubo-ovarian abscess.. Treasure Island (FL): StatPearls Publishing; 2023.
  17. Troedsson MHT. Endometritis.. In: McKinnon AO, editor. Equine reprod. Volume 271. 2nd ed. Chichester, West Sussex, UK: Wiley-Blackwell; 2011. p. 2609.
  18. Levi-Setti PE, Cirillo F, Scolaro V, Morenghi E, Heilbron F, Girardello D. Appraisal of clinical complications after 23,827 oocyte retrievals in a large assisted reproductive technology program.. Fertil Steril 2018;109:1038-1043.e1.
    doi: 10.1016/j.fertnstert.2018.02.002google scholar: lookup
  19. Ludwig AK, Glawatz M, Griesinger G, Diedrich K, Ludwig M. Perioperative and post-operative complications of transvaginal ultrasound-guided oocyte retrieval: prospective study of >1000 oocyte retrievals.. Hum Reprod 2006;21:3235-3240.
    doi: 10.1093/humrep/del278google scholar: lookup
  20. Malaluang P, Åkerholm T, Nyman G, Lindahl J, Hansson I, Morrell JM. Bacteria in the healthy equine vagina during the estrous cycle.. Theriogenology 2024;213:11-18.
    doi: 10.1016/j.theriogenology.2023.09.011google scholar: lookup
  21. Pye J, Galuppo L, Whitcomb MB, Clothier K, Byrne B. Isolation of Campylobacter fetus subspecies fetus from an abdominal abscess in an adult mare.. Can Vet J 2020;61:1307-1311.
  22. Berlin D, Kelmer G, Steinman A, Sutton GA. Successful medical management of intra-abdominal abscesses in 4 adult horses.. Can Vet J 2013;54:157-161.
  23. Davis JL. Pharmacologic principles.. In: Reed SM, Bayly WM, Sellon DC, editors. Equine internal medicine. 4th ed. St. Louis: Elsevier; 2018. p. 114.
  24. Goje O, Markwei M, Kollikonda S, Chavan M, Soper DE. Outcomes of minimally invasive management of tubo-ovarian abscess: a systematic review.. J Minim Invasive Gynecol 2021;28:556-564.
    doi: 10.1016/j.jmig.2020.09.014google scholar: lookup
  25. Claes A, Stout TAE. Success rate in a clinical equine in vitro embryo production program.. Theriogenology 2022;187:215-218.
    doi: 10.1016/j.theriogenology.2022.04.019google scholar: lookup
  26. Orellana-Guerrero D, Dini P, Santos E, De La Fuente A, Meyers S, Koshak S. Effect of transvaginal aspiration of oocytes on blood and peritoneal fluid parameters in mares.. J Equine Vet 2022;114:103949.
    doi: 10.1016/j.jevs.2022.103949google scholar: lookup

Citations

This article has been cited 3 times.
  1. Yáñez Ramil U, Jezierska S, Krupa M, Bogado Pascottini O. Fundamentals of microbiome-based therapies for reproductive tract inflammatory diseases in domestic animals. Anim Reprod 2025;22(3):e20250030.
    doi: 10.1590/1984-3143-AR2025-0030pubmed: 40933872google scholar: lookup
  2. Van den Branden E, Salamone M, Broothaers K, Peere S, Polfliet E, Dewulf M, Van Steenkiste G, van Loon G, Smits K, Govaere J. Physiological and behavioral parameters of pain and stress in mares during and after transvaginal ultrasound-guided follicular aspiration. Front Vet Sci 2025;12:1574351.
    doi: 10.3389/fvets.2025.1574351pubmed: 40271484google scholar: lookup
  3. Luis-Calero M, Fernández-Hernández P, Ortiz-Rodríguez JM, Muñoz-García CC, Jardin I, Macías-García B, González-Fernández L. Description of a new quantitative method to assess mitochondrial distribution pattern in mature equine oocytes. Vet Res Commun 2024 Jun;48(3):1867-1871.
    doi: 10.1007/s11259-024-10325-zpubmed: 38340267google scholar: lookup
Subscribe to our newsletter
Join 99,780 horse owners like you who receive our email updates on horse health and nutrition.