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EFSA journal. European Food Safety Authority2024; 22(4); e8730; doi: 10.2903/j.efsa.2024.8730

Safety and efficacy of a feed additive consisting of a tincture derived from the roots of Panax ginseng C.A.Mey. (ginseng tincture) for horses, dogs and cats (FEFANA asbl).

Abstract: Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a tincture from the roots of C.A.Mey. (ginseng tincture), when used as a sensory additive in feed for horses, dogs and cats. The product is a water/ethanol (40:60 v/v) solution, with a dry matter content of no more than 6% and a content of 0.01%-0.5% (w/w) for the sum of the two triterpene saponins ginsenoside Rb1 and ginsenoside Rg1. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the tincture is safe for horses, dogs and cats at the maximum proposed use level of 48.6, 228.7 and 162 mg/kg complete feed, respectively. The Panel also concluded that the additive is considered safe for consumers when used at the proposed conditions of use in feed for horses. Ginseng tincture should be considered as an irritant to skin and eyes, and as a dermal and respiratory sensitiser. The use of the ginseng tincture as a flavour in feed for horses was not expected to pose a risk for the environment. Since the roots of and its preparations were recognised to flavour food and their function in feed would be essentially the same, no demonstration of efficacy was considered necessary.
© 2024 European Food Safety Authority. EFSA Journal published by Wiley‐VCH GmbH on behalf of European Food Safety Authority.
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Publication Date: 2024-04-08 PubMed ID: 38591023PubMed Central: PMC11000137DOI: 10.2903/j.efsa.2024.8730Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research is about a study conducted by the European Food Safety Agency (EFSA) to understand the safe and effective usage of a tincture derived from ginseng roots in animal feed for horses, dogs, and cats.

Research Objective

  • The objective of this research was to analyze and evaluate the safety and effectiveness of a tincture extracted from the roots of Panax Ginseng. This is primarily used as a sensory additive in the feed for horses, dogs, and cats.

Product Description

  • The product under scrutiny is a water and ethanol (ratio 40:60 v/v) solution with minimal dry matter content of around 6%. The product further comprises 0.01-0.5% of the sum of two triterpenes saponins, ginsenoside Rb1, and ginsenoside Rg1. These compounds are biologically active compounds produced mainly by plants with beneficial effects on health.

Safety Analysis

  • The team, led by the FEEDAP panel, concluded after their examination that this tincture derived from ginseng roots was safe to use as feed for cats, dogs, and horses at the proposed use levels of 48.6, 228.7, and 162 mg/kg of complete feed, respectively.
  • In addition to the safety of the animals, consideration was also given to the safety of consumers who would consume these animals. Under the specified conditions of use, the additive was deemed safe for human consumption, especially when used in feed for horses.

Potential Risks

  • While the tincture was deemed safe for animal feed, the panel also identified potential risks. It was found that the ginseng tincture could cause skin and eye irritation and might sensitize the skin and respiratory system.
  • However, no environmental risks were identified from its potential use in horse feed.

Efficacy Evaluation

  • The EFSA did not expect the ginseng tincture to demonstrate a unique efficacy as it is already recognized for its flavor-enhancing capabilities in food products. Its purpose in animal feed was assumed to be essentially the same.

Conclusions

  • In conclusion, the research deemed the ginseng tincture safe and effective for use in animal feed for horses, dogs, and cats. While potential health risks were identified for skin and respiratory system sensitization, the overall evaluation substantiated safe consumer consumption and minimal impact on the environment.

Cite This Article

APA
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Kouba M, López-Alonso M, Puente SL, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Villa RE, Woutersen R, Brantom P, Chesson A, Schlatter J, Westendorf J, Dirven Y, Manini P, Dusemund B. (2024). Safety and efficacy of a feed additive consisting of a tincture derived from the roots of Panax ginseng C.A.Mey. (ginseng tincture) for horses, dogs and cats (FEFANA asbl). EFSA J, 22(4), e8730. https://doi.org/10.2903/j.efsa.2024.8730

Publication

EFSA journal. European Food Safety Authority
ISSN: 1831-4732
NlmUniqueID: 101642076
Country: United States
Language: English
Volume: 22
Issue: 4
Pages: e8730
PII: e8730

Researcher Affiliations

Bampidis, Vasileios
    Azimonti, Giovanna
      Bastos, Maria de Lourdes
        Christensen, Henrik
          Durjava, Mojca
            Kouba, Maryline
              López-Alonso, Marta
                Puente, Secundino López
                  Marcon, Francesca
                    Mayo, Baltasar
                      Pechová, Alena
                        Petkova, Mariana
                          Ramos, Fernando
                            Villa, Roberto Edoardo
                              Woutersen, Ruud
                                Brantom, Paul
                                  Chesson, Andrew
                                    Schlatter, Josef
                                      Westendorf, Johannes
                                        Dirven, Yvette
                                          Manini, Paola
                                            Dusemund, Birgit

                                              Conflict of Interest Statement

                                              If you wish to access the declaration of interests of any expert contributing to an EFSA scientific assessment, please contact interestmanagement@efsa.europa.eu.

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