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Journal of equine veterinary science2024; 105003; doi: 10.1016/j.jevs.2024.105003

Sarcoid within the oral cavity of a horse.

Abstract: Equine sarcoids are common skin tumors that are thought to be caused by cross-species infection by bovine papillomaviruses (BPV). A 16-year-old horse developed a 1cm diameter mandibular gingival mass opposite the right second premolar tooth (406) and a 2cm diameter mass close to the commissure of the lips on the same side of the mouth. The right cheek was diffusely thickened. Histology of the smaller mass revealed a proliferation of mesenchymal cells covered by hyperplastic epithelium that formed thick rete pegs. BPV2 DNA was amplified from the mass. Although the mass had been incompletely excised, there was no recurrence after 5 months. The histological features and detection of BPV2 DNA is consistent with a diagnosis of equine sarcoid. Sarcoids have not previously been reported in the oral cavity of horses. It is hypothesized that trauma to the mouth may have been important for sarcoid development. Additionally, different BPV types may have variable ability to infect the gingiva. While rare, sarcoids are a differential for an oral mass in a horse.
Publication Date: 2024-01-13 PubMed ID: 38224791DOI: 10.1016/j.jevs.2024.105003Google Scholar: Lookup
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Summary

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The study discusses a new discovery about a common skin tumors observed in horses, called sarcoids, which are believed to have been caused by the bovine papillomaviruses (BPV). A unique case was reported where such sarcoids were detected in the oral cavity of a 16-year-old horse.

Case Study Results

The study revolves around a specific case of a 16-year-old horse, which developed small masses in its oral cavity. This evidence raises the possibility of the sarcoids being formed as a result of cross-species infections by bovine papillomaviruses (BPV).

  • The two masses were located in the mandibular gingival mass opposite the right second premolar tooth and the commissure of the lips.
  • Upon examining the smaller mass of the two, it was found to have a proliferation of mesenchymal cells which were covered by hyperplastic epithelium, forming thick rete pegs.
  • Interestingly, the researchers observed that despite the mass being incompletely removed, there was no recurrence even after 5 months.
  • By detecting BPV2 DNA on the mass, the researchers concluded the mass was in fact, an equine sarcoid.

Significance Of The Findings

The findings present a previously unexplored area in the study of equine sarcoids. Sarcoids had not been detected in the oral cavity of horses until this study, which opens up new perspectives and hypotheses related to this disease.

  • The researchers hypothesize that trauma to the mouth might have played a crucial role in the development of the sarcoid.
  • There is also a possibility that different types of BPV may have variable abilities to infect the gingiva, but further research is needed to confirm this hypothesis.

Implications Of The Study

While the occurrence may be rare, the study suggests that sarcoids should be considered in the differential diagnosis when investigating oral masses in horses. This case study could serve as the starting point for further research to understand the development and treatment of equine sarcoids in the oral cavity.

Cite This Article

APA
Munday JS, Lewis MC, Leyland MH. (2024). Sarcoid within the oral cavity of a horse. J Equine Vet Sci, 105003. https://doi.org/10.1016/j.jevs.2024.105003

Publication

ISSN: 0737-0806
NlmUniqueID: 8216840
Country: United States
Language: English
Pages: 105003
PII: S0737-0806(24)00010-8

Researcher Affiliations

Munday, John S
  • School of Veterinary Science, Massey University, Palmerston North, New Zealand.. Electronic address: j.munday@massey.ac.nz.
Lewis, Michelle C
  • IDEXX Laboratories, Hamilton, New Zealand.
Leyland, Margaret H
  • Vets on Riverbank, Otaki, New Zealand.

Conflict of Interest Statement

Declaration of competing interest The authors declare they have no known competing financial interest or personal relationships that could have appeared to influence the work reported in this paper.

Citations

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