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The Journal of endocrinology1949; 6(2); 184-191; doi: 10.1677/joe.0.0060184

Serum gonadotrophin and ovarian activity in the pregnant mare.

Abstract: Shortly after Cole & Hart [1930] had reported the discovery of a gonadotrophic hormone in the blood of the mare in early pregnancy they [Cole, Howell & Hart, 1931] described the changes that occur in the ovaries throughout gestation, and associated the unusually active condition of the ovaries between the 40th and 150th day with the presence of the gonadotrophin in the blood. During this period the ovaries are very large and contain numerous follicles and a small number of functional corpora lutea. The authors claim that the latter serve initially to supplement the function of the primary corpus luteum, which even at this early stage of pregnancy is in decline, and ultimately to maintain the endometrial conditions requisite for the continuation of pregnancy. Since the above observations were made, much has been learned regarding the site of origin [Cole & Goss, 1943; Rowlands, 1947] and the biological standardization of
Publication Date: 1949-10-01 PubMed ID: 15392910DOI: 10.1677/joe.0.0060184Google Scholar: Lookup
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  • Journal Article

Summary

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The research article focuses on the role and changes of gonadotrophic hormones and ovarian activity during early pregnancy in mares. It follows the findings that these hormones, as well as the physical changes in the ovaries, are crucial for the continuation of pregnancy.

Understanding Gonadotrophin and Ovarian Activity

The study takes its basis from previous research performed by experts like Cole and Hart, who pinpointed the presence of a gonadotrophic hormone in mares’ blood in the early stages of pregnancy. Further research also indicated changes observed in the mare’s ovaries throughout gestation. Some of these changes include:

  • An unusually active condition of the ovaries between the 40th and 150th day.
  • Ovaries are very large and house numerous follicles, as well as a few functional corpora lutea.

The Role of Corpora Lutea

In addition to the mentioned changes, the researchers claimed that the functional corpora lutea serve important purposes during pregnancy:

  • They initially supplement the function of the primary corpus luteum, which starts to decline even in the early stages of pregnancy.
  • They maintain the endometrial conditions needed for keeping the pregnancy.

Further Discoveries about Gonadotrophin

More findings have come up since these initial observations were made. This includes understanding more about the place of origin of gonadotrophin and other biological discoveries. These pieces of information have been vital in comprehending the role of hormones and ovarian activity changes in mares during the early stages of their pregnancy. This serves as a continuation of expanding knowledge on equine reproduction.

Cite This Article

APA
ROWLANDS IW. (1949). Serum gonadotrophin and ovarian activity in the pregnant mare. J Endocrinol, 6(2), 184-191. https://doi.org/10.1677/joe.0.0060184

Publication

ISSN: 0022-0795
NlmUniqueID: 0375363
Country: England
Language: English
Volume: 6
Issue: 2
Pages: 184-191

Researcher Affiliations

ROWLANDS, I W

    MeSH Terms

    • Animals
    • Female
    • Gonadotropins
    • Horses
    • Humans
    • Pregnancy

    Citations

    This article has been cited 2 times.
    1. Antczak DF, de Mestre AM, Wilsher S, Allen WR. The equine endometrial cup reaction: a fetomaternal signal of significance. Annu Rev Anim Biosci 2013 Jan;1:419-42.
    2. Moor RM. Foetal homeostasis: conceptus-ovary endocrine balance. Proc R Soc Med 1968 Nov;61(11 Pt 2):1217-26.
      pubmed: 4973146