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The New England journal of medicine2022; 386(11); 1099; doi: 10.1056/NEJMc2201552

Snake Envenomation.

Abstract: No abstract available
Publication Date: 2022-03-17 PubMed ID: 35294827DOI: 10.1056/NEJMc2201552Google Scholar: Lookup
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Summary

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The research article is about the impacts of snakebite envenomation (SBE) in horses and how understanding venom components can help develop effective treatment plans.

Snakebite Envenomation in Horses

The study focuses on the effects of snakebite envenomation (SBE) in horses. The authors observed that SBE can have devastating outcomes in horses and can cause:

  • Tissue damage – the venom from the snakebite can cause severe damage to the tissues, which can lead to complications and the need for extensive treatment.
  • Cardiotoxicity – This refers to the poisonous effect of venom on the heart. It can lead to dangerous heart conditions and can be fatal if not treated in time.
  • Coagulopathy – This is a condition in which the blood’s ability to coagulate (form clots) is impaired. This can allow for continuous bleeding or clotting in horses following a snakebite.
  • Neurotoxicity – This refers to the damage caused to the nerve tissues as a result of the poisonous venom, leading to a range of neurological disorders.

Importance of Understanding Venom Components

Understanding the components of the snake venom can play a crucial role in developing effective treatment strategies for horses exposed to SBE. Each snake venom is unique, with different toxins that affect the body in different ways. By studying these components, researchers may be able to better predict the effects of a snakebite and create treatments that specifically target the symptoms caused by specific types of venom.

Antivenom Treatment

This research emphasizes that antivenom is the principle treatment for SBE in horses. Antivenom is a medication that’s designed to neutralize the venomous effects within the body, minimizing the damage and providing the horse with a better chance of recovery.

Long-term Effects

The research also highlights the potential long-term impacts that can occur in horses due to SBE, including cardiac dysfunction and lameness. Despite successful initial treatment, these long-term effects can evolve, requiring ongoing veterinary care and impacting the quality of life for the horse. Therefore, the researchers suggest the need for continuous follow-up and care after a snakebite.

Cite This Article

APA
Rushton W, Shapshak D. (2022). Snake Envenomation. N Engl J Med, 386(11), 1099. https://doi.org/10.1056/NEJMc2201552

Publication

ISSN: 1533-4406
NlmUniqueID: 0255562
Country: United States
Language: English
Volume: 386
Issue: 11
Pages: 1099

Researcher Affiliations

Rushton, William
  • Alabama Poison Information Center, Birmingham, AL wrushton@uabmc.edu.
Shapshak, Dag
  • University of Alabama Birmingham, Birmingham, AL.

MeSH Terms

  • Animals
  • Humans
  • Snake Bites / complications
  • Snake Bites / therapy
  • Snakes