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Home / Equine Research Bank / Open Vet J / Successful intra-abdominal resection of a 24 kg ovarian gran...
Open veterinary journal2023; 13(9); 1212-1218; doi: 10.5455/OVJ.2023.v13.i9.17

Successful intra-abdominal resection of a 24 kg ovarian granulosa cell tumor in a Warmblood mare.

Abstract: Granulosa cell tumors (GCTs) are the most common ovarian tumors in mares. The classical presentation of a GCT is a unilaterally enlarged ovary appearing as a multicystic honeycomb mass. In rare cases, GCTs cause hemoperitoneum as a result of the rapid growth of the tumor. The clinical diagnosis of GCT is usually based on history, rectal examination, ultrasonographic examination, and serum hormone analysis, and surgical removal of the affected ovary is the treatment of choice. The different surgical approaches are based on the dimension of the GCT. A 7-year-old mare was referred to the department for horses due to suspicion of a large colon impaction. The mare presented with clinical signs of colic, fever, and signs of hypovolemic shock. Rectal and ultrasonographic examination showed hemoperitoneum and a honey-comb mass within the abdomen, and a GCT as the cause of an acute hemoperitoneum was diagnosed based on the serum level of anti-Müllerian hormone. After stabilization of the mare, the GCT was removed through a ventral midline incision. Because of the enormous dimensions of the GCT, intra-abdominal partial resection of the tumor using a tenotomy knife was necessary to exteriorize the ovarian pedicle. At 3 months follow-up, the mare was ridden for her intended use. This report provides an approach to an uncommon case of a very large and heavy GCT.
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Publication Date: 2023-09-30 PubMed ID: 37842112PubMed Central: PMC10576582DOI: 10.5455/OVJ.2023.v13.i9.17Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article discusses a successful case of surgically removing a large 24 kg ovarian granulosa cell tumor, a common type of ovarian tumor in horses, from a mare that was initially brought in with suspected large colon impaction.

Granulosa Cell Tumors in Mares

  • Granulosa cell tumors (GCTs) are the most prevalent ovarian tumors found in mares. They usually result in a unilaterally enlarged ovary that appears as a multicystic honeycomb mass. Tumor growth can occasionally lead to hemoperitoneum, a condition characterized by blood in the peritoneal cavity. Diagnosis methodologies typically include patient history, rectal examination, ultrasonographic examination, and serum hormone analysis. The primary treatment for GCT is surgical removal.

The Case Presented

  • In this particular case, a 7-year-old mare was presented to the clinic with the suspicion of having an enlarged large colon. The mare showed symptoms of colic (abdominal discomfort commonly seen in horses), fever, and signs of hypovolemic shock, which is a severe fluid loss leading to low blood volume and inadequate perfusion. Upon rectal and ultrasonographic examination, hemoperitoneum and a honey-comb mass were discovered within the abdomen.

Diagnosis and Surgical Intervention

  • The cause of acute hemoperitoneum, in this case, was identified as GCT based on the high serum level of anti-Müllerian hormone. The procedure chosen for this specific case was a surgical removal through a ventral midline incision due to the large dimensions of the GCT. After the mare was stabilized, it was found that a partial intra-abdominal resection of the tumor was necessary to exteriorize the ovarian pedicle because of the size of the ovarian mass.

Post-Surgical Period and Conclusion

  • Three months after surgery, the mare was reported to be healthy and used for the intended purpose. This case study, therefore, portrays a unique instance of managing an unusually large and heavy GCT in a mare effectively.

Cite This Article

APA
Tommasa SD, Roth SP, Triebe T, Brehm W, Lohmann KL, Stöckle SD. (2023). Successful intra-abdominal resection of a 24 kg ovarian granulosa cell tumor in a Warmblood mare. Open Vet J, 13(9), 1212-1218. https://doi.org/10.5455/OVJ.2023.v13.i9.17

Publication

Open veterinary journal
ISSN: 2218-6050
NlmUniqueID: 101653182
Country: Libya
Language: English
Volume: 13
Issue: 9
Pages: 1212-1218

Researcher Affiliations

Tommasa, Simone Della
  • Department for Horses, University of Leipzig, Leipzig, Germany.
Roth, Susanne Pauline
  • Department for Horses, University of Leipzig, Leipzig, Germany.
Triebe, Theresa
  • Department for Horses, University of Leipzig, Leipzig, Germany.
Brehm, Walter
  • Department for Horses, University of Leipzig, Leipzig, Germany.
Lohmann, Katharina Luise
  • Department for Horses, University of Leipzig, Leipzig, Germany.
Stöckle, Sabita Diana
  • Department for Horses, University of Leipzig, Leipzig, Germany.

MeSH Terms

  • Animals
  • Horses
  • Female
  • Granulosa Cell Tumor / diagnosis
  • Granulosa Cell Tumor / surgery
  • Granulosa Cell Tumor / veterinary
  • Hemoperitoneum / veterinary
  • Horse Diseases / diagnosis
  • Horse Diseases / surgery
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / surgery
  • Ovarian Neoplasms / veterinary

Conflict of Interest Statement

The authors declare that there is no conflict of interest

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