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Journal of equine veterinary science2024; 133; 105015; doi: 10.1016/j.jevs.2024.105015

The effect of feeding a commercial feedstuff on gastric squamous gastric disease (ESGD) healing and prevention of recurrence.

Abstract: Feedstuffs are often recommended to mitigate potential damage from acid associated with equine squamous gastric disease (ESGD). In acidic conditions, pectin alters its structure to one like mucus and binds the stomach mucosa, whilst alfalfa has a strong intrinsic acid buffering capacity. The study aimed to determine whether feeding a commercial beet pulp/alfalfa/oat fibre mix aids ESGD healing and/or prevention of recurrence. Ten adult horses with naturally occurring ESGD were included. All animals were treated with omeprazole as per the attending veterinarian's recommendation and randomly allocated to also be fed a commercial beet pulp/alfalfa/oat fibre mix (1Kg/horse divided into 2 meals/day; n=5) or no additional feed (n=5) for one month. Gastroscopy was then repeated to assess response to therapy. If the ESGD had healed, omeprazole therapy was discontinued, and the commercial feed given to all horses for a further month. Gastroscopy was repeated to determine ESGD recurrence. The mean (±SD) age of the horses was 11.6 (±3.8) years; 4 mares and 6 geldings; various breeds were represented; and the median (range) initial ESGD grade was 2 (2-4). ESGD had healed (grade 0/4) in all animals after one month. After a further month, ESGD had recurred in significantly (p=0.04) more animals that did not receive the commercial feed initially (3/5; 60%; mean [range] ESGD grade 3 [0,4]) compared to those that did (0/5; 0%; mean [range] ESGD grade 0 [0,0]). Thus, the commercial beet pulp/alfalfa/oat fibre mix aided prevention of ESGD recurrence when fed during the healing and prevention phases.
Publication Date: 2024-01-27 PubMed ID: 38281606DOI: 10.1016/j.jevs.2024.105015Google Scholar: Lookup
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  • Randomized Controlled Trial
  • Veterinary
  • Journal Article

Summary

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This study investigates the impact of a commercial beet pulp/alfalfa/oat fibre mix feed on the healing and prevention of equine squamous gastric disease (ESGD) recurrence in horses. The results suggest that the commercial feedstuff aids in preventing ESGD recurrence when included in a horse’s diet during the healing phase and afterward.

Objective of the Research

The primary objective of this research was to determine whether a commercial feedstuff, comprised substances known to help combat symptoms of ESGD, could facilitate ESGD healing and deter recurrences.

  • ESGD is a common equine disease associated with acid damage to the horse’s stomach lining.
  • Pectin, found in beet pulp, changes its structure under acidic conditions to resemble mucous, which then binds to the horse’s stomach mucosa, thereby offering protection against acid damage.
  • Alfalfa, another component of the commercial feed, has a strong innate acid-buffering capacity, providing a natural defense against acid-induced damage.

Methodology

  • The study included ten horses diagnosed with ESGD. The horses were of various ages, breeds, and included both mares and geldings.
  • All the horses were treated with omeprazole according to the attending veterinarian’s recommendation.
  • The horses were then randomized into two groups: one that additionally received the commercial beet pulp/alfalfa/oat fibre mix feed and another group that did not receive any additional feed.
  • The study duration was one month, at the end of which gastroscopy was performed to evaluate the response to therapy.
  • If the ESGD had healed, omeprazole therapy was ceased, and the commercial feed was provided to all horses for another month. ESGD recurrence was checked via gastroscopy after this period.

Findings

  • After a month of treatment, ESGD was found to have healed in all horses.
  • However, at the end of the second month (during which all horses received the commercial feed), ESGD had recurred in significantly more horses that had not been fed the commercial feed during the initial treatment month.
  • The feed mix thus appears to have played a crucial role in preventing ESGD recurrence.

Implications

  • The commercial beet pulp/alfalfa/oat fibre mix feed appears to be a promising aid in both the healing process and prevention of ESGD recurrence in horses.
  • While the currently accepted treatment involves a medication, omeprazole, this research suggests that diet alterations using the feed mix can offer additional support in handling ESGD.
  • This commercial feed could potentially serve as an essential supplementary tool in managing equine health, specifically in the regulation and prevention of gastric diseases.

Cite This Article

APA
Menzies-Gow NJ, Shurlock T. (2024). The effect of feeding a commercial feedstuff on gastric squamous gastric disease (ESGD) healing and prevention of recurrence. J Equine Vet Sci, 133, 105015. https://doi.org/10.1016/j.jevs.2024.105015

Publication

ISSN: 0737-0806
NlmUniqueID: 8216840
Country: United States
Language: English
Volume: 133
Pages: 105015

Researcher Affiliations

Menzies-Gow, N J
  • Department of Clinical Sciences and Services, Royal Veterinary College, Hawkshead Lane, North Mymms, Herts. AL9 7TA. United Kingdom. Electronic address: nmenziesgow@rvc.ac.uk.
Shurlock, T
  • West Lane House, Bishopdale, Leyburn, North Yorkshire. DL8 3TG. United Kingdom.

MeSH Terms

  • Horses
  • Animals
  • Female
  • Male
  • Plant Breeding
  • Stomach Diseases / veterinary
  • Omeprazole / pharmacology
  • Omeprazole / therapeutic use
  • Horse Diseases / drug therapy
  • Horse Diseases / prevention & control
  • Medicago sativa
  • Carcinoma, Squamous Cell / veterinary

Conflict of Interest Statement

Declaration of competing interest Tom Shurlock is an equine nutrition consultant for the study funder, British Horse Feeds. Nicola Menzies-Gow does not have any financial or personal relationships that could inappropriately influence or bias the content of the paper.