Treatment of acute superficial digital flexor tendon injury in horses with polysulphated glycosaminoglycan.
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
This research study investigates the effect of administering polysulphated glycosaminoglycan via intramuscular injections for treating acute injuries in the superficial digital flexor tendon in horses. The results indicated that in 80% of cases, the drug was found to be beneficial.
Methodology of the Study
The study employed a specific treatment plan for horses suffering from acute injuries in their superficial digital flexor tendon. The primary elements of their methodology consisted of:
- Giving the horses a course of seven intramuscular injections of 500 mg polysulphated glycosaminoglycan at four-day intervals.
- Conducting clinical assessments of the lesions by a veterinary surgeon at distinct times: during each injection, and 14 and 28 days following the last injection.
Sample Size and Data Collection
The scientists in charge of the study engaged in:
- Administering 150 courses of the drug.
- Collecting completed assessment forms for 80 cases.
- Gathering long-term follow-up data for 19 separate cases.
Results of the Study
The results from the study were predominantly based on subjective assessments by veterinary surgeons. According to these assessments:
- In 80% of the cases, the polysulphated glycosaminoglycan treatment was considered valuable in handling acute tendon injuries.
Conclusion
Based on the data gathered and assessments made, the study concluded that the systematic application of polysulphated glycosaminoglycan appears to be a beneficial treatment strategy for acute superficial digital flexor tendon injury in horses.
Cite This Article
Publication
Researcher Affiliations
- Department of Anatomy, University of Bristol, School of Veterinary Science.
MeSH Terms
- Animals
- Dose-Response Relationship, Drug
- Female
- Follow-Up Studies
- Gait / physiology
- Glycosaminoglycans / administration & dosage
- Glycosaminoglycans / standards
- Glycosaminoglycans / therapeutic use
- Horse Diseases / drug therapy
- Horse Diseases / physiopathology
- Horses
- Injections, Intramuscular
- Male
- Polysaccharides / administration & dosage
- Polysaccharides / standards
- Polysaccharides / therapeutic use
- Tendon Injuries / drug therapy
- Tendon Injuries / physiopathology
- Tendon Injuries / veterinary
- Time Factors
- Treatment Outcome
Citations
This article has been cited 1 times.- Khan KM, Cook JL, Bonar F, Harcourt P, Astrom M. Histopathology of common tendinopathies. Update and implications for clinical management. Sports Med 1999 Jun;27(6):393-408.