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The Veterinary record1996; 139(17); 413-416; doi: 10.1136/vr.139.17.413

Treatment of acute superficial digital flexor tendon injury in horses with polysulphated glycosaminoglycan.

Abstract: Horses with acute injuries of the superficial digital flexor tendon were treated with a course of seven intramuscular injections of 500 mg of polysulphated glycosaminoglycan at four-day intervals. Clinical assessments of the lesions were made by a veterinary surgeon at the time of each injection and 14 and 28 days after the last injection. A total of 150 courses of the drug were administered and adequately completed assessment forms were returned for 80 cases. Long-term follow-up data were obtained for 19 cases. The subjective assessments by the veterinary surgeons showed that in 80 per cent of cases the drug was felt to be of value in the treatment of acute tendon injury.
Publication Date: 1996-10-26 PubMed ID: 8923715DOI: 10.1136/vr.139.17.413Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research study investigates the effect of administering polysulphated glycosaminoglycan via intramuscular injections for treating acute injuries in the superficial digital flexor tendon in horses. The results indicated that in 80% of cases, the drug was found to be beneficial.

Methodology of the Study

The study employed a specific treatment plan for horses suffering from acute injuries in their superficial digital flexor tendon. The primary elements of their methodology consisted of:

  • Giving the horses a course of seven intramuscular injections of 500 mg polysulphated glycosaminoglycan at four-day intervals.
  • Conducting clinical assessments of the lesions by a veterinary surgeon at distinct times: during each injection, and 14 and 28 days following the last injection.

Sample Size and Data Collection

The scientists in charge of the study engaged in:

  • Administering 150 courses of the drug.
  • Collecting completed assessment forms for 80 cases.
  • Gathering long-term follow-up data for 19 separate cases.

Results of the Study

The results from the study were predominantly based on subjective assessments by veterinary surgeons. According to these assessments:

  • In 80% of the cases, the polysulphated glycosaminoglycan treatment was considered valuable in handling acute tendon injuries.

Conclusion

Based on the data gathered and assessments made, the study concluded that the systematic application of polysulphated glycosaminoglycan appears to be a beneficial treatment strategy for acute superficial digital flexor tendon injury in horses.

Cite This Article

APA
Dow SM, Wilson AM, Goodship AE. (1996). Treatment of acute superficial digital flexor tendon injury in horses with polysulphated glycosaminoglycan. Vet Rec, 139(17), 413-416. https://doi.org/10.1136/vr.139.17.413

Publication

ISSN: 0042-4900
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 139
Issue: 17
Pages: 413-416

Researcher Affiliations

Dow, S M
  • Department of Anatomy, University of Bristol, School of Veterinary Science.
Wilson, A M
    Goodship, A E

      MeSH Terms

      • Animals
      • Dose-Response Relationship, Drug
      • Female
      • Follow-Up Studies
      • Gait / physiology
      • Glycosaminoglycans / administration & dosage
      • Glycosaminoglycans / standards
      • Glycosaminoglycans / therapeutic use
      • Horse Diseases / drug therapy
      • Horse Diseases / physiopathology
      • Horses
      • Injections, Intramuscular
      • Male
      • Polysaccharides / administration & dosage
      • Polysaccharides / standards
      • Polysaccharides / therapeutic use
      • Tendon Injuries / drug therapy
      • Tendon Injuries / physiopathology
      • Tendon Injuries / veterinary
      • Time Factors
      • Treatment Outcome

      Citations

      This article has been cited 1 times.
      1. Khan KM, Cook JL, Bonar F, Harcourt P, Astrom M. Histopathology of common tendinopathies. Update and implications for clinical management. Sports Med 1999 Jun;27(6):393-408.