The British journal of radiology.
Publisher:
British Institute of Radiology.
Frequency: Monthly
Country: England
Language: English
Author(s):
British Institute of Radiology (1958), British Institute of Radiology Incorporated with the Röntgen Society
Start Year:1928 -
ISSN:
0007-1285 (Print)
1748-880X (Electronic)
0007-1285 (Linking)
1748-880X (Electronic)
0007-1285 (Linking)
Impact Factor
2.6
2022
| NLM ID: | 0373125 |
| (DNLM): | B35460000(s) |
| (OCoLC): | 01537310 |
| Coden: | BJRAAP |
| LCCN: | 49040049 |
| Classification: | W1 BR624R |
Anti-lipopolysaccharide toxin therapy for whole body X-irradiation overdose. Death in humans from ionising radiation overexposure in the 3-8 Gy (300-800 rad) range is in part due to the toxaemia caused by the entry of gram-negative bacteria and/or their lipopolysaccharide toxin (LPS) into the blood circulation through the walls of partially denuded gut. Anti-LPS hyperimmune equine plasma was evaluated for its ability to lower irradiation-induced lethality. Mice were irradiated with 6.3 Gy (630 rad) and six days later received equine Anti-LPS hyperimmune plasma, control plasma or saline. Mortalities in the three groups were 58%, 92% and 79% (p less than 0.01) respective...