Chemistry : a European journal.
Publisher:
Wiley-VCH
Frequency: 48 times a year,
Country: Germany
Language: English
Author(s):
Gesellschaft Deutscher Chemiker., EU ChemSoc., ChemPubSoc Europe., Asian Chemical Editorial Society.
Start Year:1995 -
ISSN:
0947-6539 (Print)
1521-3765 (Electronic)
0947-6539 (Linking)
1521-3765 (Electronic)
0947-6539 (Linking)
Impact Factor
4.3
2023
| NLM ID: | 9513783 |
| (DNLM): | SR0085220(s) |
| (OCoLC): | 32677914 |
| Coden: | CEUJED |
| LCCN: | sn 95026440 |
| Classification: | W1 CH356 |
Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin. X-ray structures of homopolymeric human L-ferritin and horse spleen ferritin were solved by freezing protein crystals at different time intervals after exposure to a ferric salt and revealed the growth of an octa-nuclear iron cluster on the inner surface of the protein cage with a key role played by some glutamate residues. An atomic resolution view of how the cluster formation develops starting from a (μ -oxo)tris[(μ -glutamato-κO:κO')](glutamato-κO)(diaquo)triiron(III) seed is provided. The results support the idea that iron biomineralization in ferritin is a process initiating at the l...