COPD.
Publisher:
Marcel Dekker,. London : Informa Healthcare
Frequency: Quarterly, 2005-
Country: England
Language: English
Start Year:2004 -
ISSN:
1541-2555 (Print)
1541-2563 (Electronic)
1541-2563 (Linking)
1541-2563 (Electronic)
1541-2563 (Linking)
Impact Factor
2.2
2022
| NLM ID: | 101211769 |
| (OCoLC): | 50389006 |
| Coden: | CJCOA3 |
| LCCN: | 2002214773 |
| Classification: | W1 CO825S |
Pharmacological characterization of the interaction between tiotropium and olodaterol administered at 5:5 concentration-ratio in equine bronchi. Equine airways represent a suitable ex vivo model to study the functional impact of pharmacological treatments on human chronic obstructive pulmonary disorders, such as asthma and chronic obstructive pulmonary disease (COPD). We aimed to characterize the pharmacological interaction between the long-acting muscarinic antagonist (LAMA) tiotropium and the long-acting β-agonist (LABA) olodaterol in equine airways. The effect of tiotropium and olodaterol, administered alone and in combination at the ratio of concentrations reproducing ex vivo the concentration-ratio delivered by the currently avai...