Fundamental & clinical pharmacology.
Publisher:
Elsevier,. Oxford : Blackwell Science (2001)
Frequency: Six no. a year, 1991-
Country: England
Language: English
Author(s):
Association des pharmacologistes (France), Société française de pharmacologie., Société française de pharmacologie et de thérapeutique., Federation of the European Pharmacological Societies., European Society of Cardiology. Working Group on Cardiovascular Pharmacology and Drug Therapy.
Start Year:1987 -
ISSN:
0767-3981 (Print)
1472-8206 (Electronic)
0767-3981 (Linking)
1472-8206 (Electronic)
0767-3981 (Linking)
Impact Factor
2.9
2022
| NLM ID: | 8710411 |
| (DNLM): | SR0057257(s) |
| (OCoLC): | 16462006 |
| Coden: | FCPHEZ |
| Classification: | W1 FU538TS |
Effect of corticosteroids on articular cartilage: have animal studies said everything? Intra-articular (IA) corticosteroids (CS) have been used in the treatment of osteoarthritis for many years, although their effects on articular cartilage are not fully understood. To identify whether previous animal studies have provided enough evidence about the effects of CS, we undertook a systematic review that identified 35 relevant in vivo animal experimental studies between 1965 and 2014 assessing the effects of CS on either normal cartilage, or in either induced osteoarthritis (OA) or synovitis. The quality of the methodology was assessed. Deleterious effects, both structural and bioc...