Journal of clinical immunology.
Publisher:
Plenum,. Amsterdam : Springer
Frequency: Eight no. a year, 2013-
Country: Netherlands
Language: English
Start Year:1981 -
ISSN:
0271-9142 (Print)
1573-2592 (Electronic)
0271-9142 (Linking)
1573-2592 (Electronic)
0271-9142 (Linking)
Impact Factor
9.1
2022
| NLM ID: | 8102137 |
| (DNLM): | J16735000(s) |
| (OCoLC): | 06742940 |
| Coden: | JCIMDO |
| LCCN: | 81641145 |
| Classification: | W1 JO588DE |
Common variable immunodeficiency in horses is characterized by B cell depletion in primary and secondary lymphoid tissues. Common variable immunodeficiency (CVID) in horse patients is characterized by late-onset B cell lymphopenia or depletion, hypo- or agammaglobulinemia, impaired humoral response to tetanus toxoid vaccination, and recurrent fevers and bacterial infections. Conclusions: This study describes the clinical and immunologic findings of 14 affected horses (average age 10.7 +/- 4.4 years) of both genders (six females, eight males) and different breeds (eight Thoroughbreds, four Quarter Horses, one Warmblood, one Pony). Serial immunological testing in peripheral blood revealed persistent, severe B cell l...