Journal of medicinal food.
Publisher:
Mary Ann Liebert, Inc.,
Frequency: Twelve no. a year, 2010-
Country: United States
Language: English
Start Year:1998 -
ISSN:
1096-620X (Print)
1557-7600 (Electronic)
1096-620X (Linking)
1557-7600 (Electronic)
1096-620X (Linking)
Impact Factor
2.4
2022
| NLM ID: | 9812512 |
| (DNLM): | SR0092301(s) |
| (OCoLC): | 37830714 |
| Coden: | JMFOFJ |
| LCCN: | 98657820 |
| Classification: | W1 JO759 |
Avocado/Soybean Unsaponifiables, Glucosamine and Chondroitin Sulfate Combination Inhibits Proinflammatory COX-2 Expression and Prostaglandin E2 Production in Tendon-Derived Cells. Tendinopathy, a common disorder in man and horses, is characterized by pain, dysfunction, and tendon degeneration. Inflammation plays a key role in the pathogenesis of tendinopathy. Tendon cells produce proinflammatory molecules that induce pain and tissue deterioration. Currently used nonsteroidal anti-inflammatory drugs are palliative but have been associated with adverse side effects prompting the search for safe, alternative compounds. This study determined whether tendon-derived cells' expression of proinflammatory cyclooxygenase (COX)-2 and production of prostaglandin E2 (PGE) could be a...