Journal of pediatric gastroenterology and nutrition.
Publisher:
Raven Press,. Philadelphia, PA : Lippincott Williams & Wilkins (1998)
Frequency: Monthly,
Country: United States
Language: English
Author(s):
North American Society for Pediatric Gastroenterology and Nutrition., European Society for Paediatric Gastroenterology and Nutrition., European Society for Pediatric Gastroenterology, Hepatology and Nutrition.
Start Year:1982 -
Identifiers
| ISSN: | 0277-2116 (Print) 1536-4801 (Electronic) 0277-2116 (Linking) |
| NLM ID: | 8211545 |
| (DNLM): | J33930000(s) |
| (OCoLC): | 07520467 |
| Coden: | JPGND6 |
| LCCN: | sc 82007546 |
| Classification: | W1 JO828E |
Application of organ culture of small intestine to the investigation of enterocyte damage by equine rotavirus. We used organ culture of jejunal mucosal explants obtained from ponies aged between 2 and 12 months to study enterocyte damage by group A strains of equine rotavirus. Electron microscopy of jejunal explants maintained for < or = 48 h in the presence of organ culture medium alone showed that enterocytes were structurally intact and had a densely packed brush border and overlying mucus. Similarly, examination of explants maintained in the presence of rotavirus for 48 h revealed no apparent ultrastructural abnormalities. However, obvious replication and assembly of virus in enterocytes had occ...