Topic:Monoamine Oxidase
Monoamine oxidase (MAO) is an enzyme found in various tissues, including the brain, liver, and gastrointestinal tract of horses. It is involved in the catabolism of monoamines, which are neurotransmitters such as serotonin, dopamine, and norepinephrine. The enzyme exists in two isoforms, MAO-A and MAO-B, each with distinct substrate specificities and tissue distributions. MAO plays a role in regulating mood, behavior, and neurological functions by controlling the levels of monoamines. Research into equine MAO activity provides insights into behavioral conditions, stress responses, and potential therapeutic targets. This page compiles peer-reviewed research studies and scholarly articles that explore the biochemical properties, regulation, and implications of monoamine oxidase in equine physiology and behavior.
Toxicity of Palicourea marcgravii: combined effects of fluoroacetate, N-methyltyramine and 2-methyltetrahydro-beta-carboline. Feeding experiments carried out with cattle and horses could prove the toxic effects of P. marcgravii (Rubiaceae) in all cases. The typical symptoms of "sudden death", however, are observed in ruminants only. This difference could not be explained so far. Apart from fluoroacetate, two more substances also have influence the toxic effects and have been isolated from P. marcgravii for the first time: N-methyltyramine and 2-methyltetrahydro-beta-carboline (2-Me THBC). Structure elucidation of these compounds is mainly accomplished by 1H-NMR, 13C-NMR and MS techniques. Due to the small quantity of...