A study of diurnal changes in cortisol and glucose levels and FDPA activity in foals during the first 13 weeks of life and in their lactating mothers.
Abstract: 1. In six standard-bred mares and their foals diurnal changes in the cortisol and glucose levels and in FDPA activity were studies for 13 weeks of foal life. 2. In the cortisol level diurnal rhythm was found in the 3rd, 7th and 11th week of foal life and in the 11th week of lactation in mares. 3. In mares the mean diurnal cortisol level changed from 32 ng/ml in the first week to 57 in the 11th week and in foals from 24 in the first week to 16 ng/ml in the 11th week. 4. In the glucose level no diurnal rhythm was observed. 5. In mares the mean diurnal glucose level after parturition was about 58 mg/100 ml and increased to 83-85 mg/100 ml. In foals it changed from 105 to 128 mg/100 ml. 6. In the activity of FDPA no diurnal rhythm was observed. 7. The mean activity of FDPA changed in mares from 3.3 to 4.4 U and in foals from 5.7 to 7.5 U.
Publication Date: 1989-01-01 PubMed ID: 2573474DOI: 10.1016/0300-9629(89)90550-1Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The article discusses a study on the daily changes in cortisol and glucose levels, and FDPA activity in foals during their first 13 weeks, as well as in their lactating mothers.
Objective and Study Design
- This research was centered on exploring the daily alterations in cortisol and glucose levels, as well as FDPA activity in foals during their first 13 weeks of life, and also in their lactating mothers.
- The study involved six standard-bred mares and their foals. The measurements were taken during various weeks throughout the 13-week period.
Cortisol Levels
- Researchers found a daily rhythm in cortisol levels in the 3rd, 7th, and 11th week of the foal’s life, and the 11th week of lactation in mares.
- In mares, the average daily cortisol level increased from 32 ng/ml in the first week to 57 ng/ml in the 11th week.
- In contrast, foals showed a decrease in their cortisol levels from 24 ng/ml in the first week to 16 ng/ml in the 11th week.
Glucose Levels
- Unlike cortisol, glucose levels did not exhibit a daily rhythm.
- In mares, the mean daily glucose level after giving birth was around 58 mg/100 ml, which then increased to 83-85 mg/100 ml.
- For foals, the glucose level increased from 105 to 128 mg/100 ml throughout the study.
FDPA Activity
- Regarding the activity of FDPA, also known as Flinders Sensitive Line Derived Pro-Apoptotic Sequences, no daily rhythm was observed either.
- The mean activity of FDPA increased in mares from 3.3 to 4.4 U, and in foals, it increased from 5.7 to 7.5 U during the 13 week period.
Conclusion
- This research provides new insights into the physiological alterations in cortisol and glucose levels, and FDPA activity in both foals and lactating mares.
- The daily variations in these factors, particularly cortisol, suggest an adaptation process in the foal’s life during the initial weeks.
Cite This Article
APA
Flisińska-Bojanowska A, Gill J, Komosa M, Kompanowska-Jezierska E.
(1989).
A study of diurnal changes in cortisol and glucose levels and FDPA activity in foals during the first 13 weeks of life and in their lactating mothers.
Comp Biochem Physiol A Comp Physiol, 94(2), 283-288.
https://doi.org/10.1016/0300-9629(89)90550-1 Publication
Researcher Affiliations
- Department of Vertebrate Animal Physiology, University of Warsaw, Poland.
MeSH Terms
- Animals
- Animals, Newborn / blood
- Animals, Newborn / growth & development
- Blood Glucose / metabolism
- Circadian Rhythm
- Female
- Fructose-Bisphosphate Aldolase / blood
- Horses / blood
- Horses / growth & development
- Hydrocortisone / blood
- Lactation / blood
- Pregnancy
Citations
This article has been cited 3 times.- Elder E, Wong D, Johnson K, Robertson H, Marner M, Dembek K. Assessment of the hypothalamic-pituitary-adrenocortical axis function using a vasopressin stimulation test in neonatal foals. J Vet Intern Med 2023 Sep-Oct;37(5):1881-1888.
- Boujard T, Leatherland JF. Circadian pattern of hepatosomatic index, liver glycogen and lipid content, plasma non-esterified fatty acid, glucose, T3, T 4, growth hormone and cortisol concentrations in Oncorhynchus mykiss held under different photoperiod regimes and fed using demand-feeders. Fish Physiol Biochem 1992 Aug;10(2):111-22.
- Fazio E, Medica P, Aronica V, Grasso L, Ferlazzo A. Circulating beta-endorphin, adrenocorticotrophic hormone and cortisol levels of stallions before and after short road transport: stress effect of different distances. Acta Vet Scand 2008 Mar 3;50(1):6.
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