An equine respiratory virus with enterovirus properties.
Abstract: A VIRUS was isolated in monkey kidney tissue cultures from the fæces of 13 of 290 horses held in the stables of the Wellcome Research Laboratories. One of these strains was selected for investigation. Rabbit hyperimmune serum prepared against it and possessing a neutralizing titre of 1/4,000 neutralized all 12 remaining isolates to the same titre.
Publication Date: 1962-08-04 PubMed ID: 14487261DOI: 10.1038/195519a0Google Scholar: Lookup
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- Journal Article
Summary
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The research article highlights the isolation and investigation of a virus with enterovirus properties found in horses, specifically deriving from their faeces, and grown in monkey kidney tissue cultures.
Research Methodology
- The research was conducted by collecting faecal samples from a group of 290 horses housed in the stables of the Wellcome Research Laboratories.
- From these samples, the researchers managed to isolate an unknown virus in monkey kidney tissue cultures from the horse faeces of 13 distinct horses.
- One of the isolated strains was chosen for an in-depth investigation to identify its properties.
Results of the Investigation
- The team also produced a hyperimmune serum using rabbits, specifically against the chosen virus strain.
- The prepared serum demonstrated a neutralizing titre of 1/4,000, meaning that it could effectively neutralize the virus at that concentration.
- This serum was used to test the remaining 12 virus isolates and interestingly, it neutralized all 12 remaining isolates to the same titre.
Significance of the Study
- This result implies that all 13 strains (including the initially investigated one) are likely similar in nature, potentially belonging to the same viral family or type.
- The identification of a virus with enterovirus properties in horse faeces opens up new avenues for further research into equine health and diseases, as enteroviruses are often associated with various illnesses in mammals.
- It also highlights the need for rigorous sanitary standards in equine stables to prevent possible viral outbreaks.
Cite This Article
APA
PLUMMER G.
(1962).
An equine respiratory virus with enterovirus properties.
Nature, 195, 519-520.
https://doi.org/10.1038/195519a0 Publication
Researcher Affiliations
MeSH Terms
- Animals
- Enterovirus
- Horses
- Viruses
Citations
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