Case report: tripelennamine in the treatment of skin disorders in horses.
- Journal Article
Summary
The study reports a successful treatment of a horse’s skin allergy at the South Dakota State University. The treatment involved compounded tripelennamine hydrochloride injection and a topical gel comprising of diphenhydramine hydrochloride, hydrocortisone, and tripelennamine hydrochloride.
Introduction
This research focuses on a case study involving a horse from the South Dakota State University equestrian team that experienced itchy skin due to an allergy. The allergy was not exclusive to this horse, as other horses were similarly affected. It was tackling this issue that prompted the exploration of compounded tripelennamine hydrochloride injection and a combination of diphenhydramine hydrochloride, hydrocortisone, and tripelennamine hydrochloride in a form of a topical gel as a possible treatment for the condition.
Methods
- The researchers administered a mixture of tripelennamine hydrochloride injection and topical gel containing diphenhydramine hydrochloride, hydrocortisone, and tripelennamine hydrochloride to treat the horse’s skin allergy.
- The tripelennamine hydrochloride injection was compounded, which typically involves tailoring a medication to fit the unique needs of the patient, in this case, the horse with the skin allergy.
- The use of the aforementioned components in a gel format was designed to augment the effect of the treatment by providing a direct, localized impact on the affected skin areas.
Results
- The results of the treatment were deemed successful as the horse’s condition improved significantly after the administration of the treatment.
- While the research is a case report, it indicates the potential effectiveness of the used combination of drugs in treating skin allergies in horses, particularly when the condition is not responsive to regular treatments.
Conclusion
The research concludes that the use of compounded tripelennamine hydrochloride injection in conjunction with a topical gel comprising of diphenhydramine hydrochloride, hydrocortisone, and tripelennamine hydrochloride can be an effective method of treating skin allergies in horses. However, since this study involves a single case, further research is needed to verify the utility and effectiveness of this treatment in a larger population and other types of skin conditions in horses. The findings, nonetheless, offer a promising direction for future investigations.
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Publication
Researcher Affiliations
- Dakota Compounding Pharmacy, Brookings, South Dakota.