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Complete mitochondrial genome of an extinct Equus (Sussemionus) ovodovi specimen from Denisova cave (Altai, Russia).
Abstract: is an extinct subgenus of first characterized and delineated in 2010. The almost complete mitochondrial genome is available only for a single specimen of - a 40,000 years old from Proskuryakova cave (Khakassia, Russia). Our studies of ancient horses from Denisova cave (Altai, Russia) revealed mitochondrial DNA of this species in a 32,000 years old sample. Using alignments to multiple mitochondrial genomes of non-caballine equids, we recovered 100% complete mitochondrial genome of for the first time. Phylogenetic analysis demonstrates close relationship between this individual and the one previously described in Khakassia.
© 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
Publication Date: 2017-02-06 PubMed ID: 33473722PubMed Central: PMC7800821DOI: 10.1080/23802359.2017.1285209Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
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This research deals with the extinct subgenus of Equus, Sussemionus ovodovi. The scientists have successfully acquired the complete mitochondrial genome from a 32,000-year-old sample from an extinct equus specimen found in Denisova cave in Russia. The findings have also demonstrated a close relationship between this individual and a previously described one found in Khakassia, Russia.
Objective of the Research
- The main objective of the research was to extract and investigate the complete mitochondrial genome of an extinct Equus known as Sussemionus ovodovi, from a fossil specimen.
Study and Methods
- The researchers conducted the study on ancient horses discovered from the Denisova cave in Altai, Russia.
- They processed a 32,000 year-old sample to retrieve the mitochondrial DNA of this extinct species.
- The researchers then utilized alignments to various mitochondrial genomes of non-caballine equids to achieve a complete mitochondrial genome recovery.
Results and Findings
- The study successfully resulted in the recovery of a 100% complete mitochondrial genome of Sussemionus ovodovi for the very first time.
- The researchers conducted phylogenetic analysis which showcased a close relationship between the analyzed individual and a previously described one located in Khakassia, Russia.
Significance of the Study
- The study sets a precedent by attaining an entire mitochondrial genome from an extinct subspecies which will set the path for further investigations in the field.
- The results can contribute significantly to evolutionary biology by deepening the understanding of extinct species and their genetic makeup.
Cite This Article
APA
Druzhkova AS, Makunin AI, Vorobieva NV, Vasiliev SK, Ovodov ND, Shunkov MV, Trifonov VA, Graphodatsky AS.
(2017).
Complete mitochondrial genome of an extinct Equus (Sussemionus) ovodovi specimen from Denisova cave (Altai, Russia).
Mitochondrial DNA B Resour, 2(1), 79-81.
https://doi.org/10.1080/23802359.2017.1285209 Publication
Researcher Affiliations
- Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia.
- Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia.
- Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia.
- Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russia.
- Institute of Archaeology and Ethnography SB RAS, Novosibirsk, Russia.
- Institute of Archaeology and Ethnography SB RAS, Novosibirsk, Russia.
- Institute of Archaeology and Ethnography SB RAS, Novosibirsk, Russia.
- Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia.
- Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russia.
- Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, Russia.
- Department of Natural Sciences, Novosibirsk State University, Novosibirsk, Russia.
Conflict of Interest Statement
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.
References
This article includes 7 references
- Druzhkova AS, Thalmann O, Trifonov VA, Leonard JA, Vorobieva NV, Ovodov ND, Graphodatsky AS, Wayne RK. Ancient DNA analysis affirms the canid from Altai as a primitive dog.. PLoS One 2013;8(3):e57754.
- Eisenmann V, Vasiliev S. Unexpected finding of a new Equus species (Mammalia, Perissodactyla) belonging to a supposedly extinct subgenus in late Pleistocene Deposits of Khakassia (Southwestern Siberia). Geodiversitas 33:519–530.
- Maricic T, Whitten M, Pääbo S. Multiplexed DNA sequence capture of mitochondrial genomes using PCR products.. PLoS One 2010 Nov 16;5(11):e14004.
- Orlando L. A 400,000-year-old mitochondrial genome questions phylogenetic relationships amongst archaic hominins: using the latest advances in ancient genomics, the mitochondrial genome sequence of a 400,000-year-old hominin has been deciphered.. Bioessays 2014 Jun;36(6):598-605.
- Orlando L, Metcalf JL, Alberdi MT, Telles-Antunes M, Bonjean D, Otte M, Martin F, Eisenmann V, Mashkour M, Morello F, Prado JL, Salas-Gismondi R, Shockey BJ, Wrinn PJ, Vasil'ev SK, Ovodov ND, Cherry MI, Hopwood B, Male D, Austin JJ, Hänni C, Cooper A. Revising the recent evolutionary history of equids using ancient DNA.. Proc Natl Acad Sci U S A 2009 Dec 22;106(51):21754-9.
- Schubert M, Ermini L, Der Sarkissian C, Jónsson H, Ginolhac A, Schaefer R, Martin MD, Fernández R, Kircher M, McCue M, Willerslev E, Orlando L. Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX.. Nat Protoc 2014 May;9(5):1056-82.
- Vilstrup JT, Seguin-Orlando A, Stiller M, Ginolhac A, Raghavan M, Nielsen SC, Weinstock J, Froese D, Vasiliev SK, Ovodov ND, Clary J, Helgen KM, Fleischer RC, Cooper A, Shapiro B, Orlando L. Mitochondrial phylogenomics of modern and ancient equids.. PLoS One 2013;8(2):e55950.
Citations
This article has been cited 2 times.- Cai D, Zhu S, Gong M, Zhang N, Wen J, Liang Q, Sun W, Shao X, Guo Y, Cai Y, Zheng Z, Zhang W, Hu S, Wang X, Tian H, Li Y, Liu W, Yang M, Yang J, Wu D, Orlando L, Jiang Y. Radiocarbon and genomic evidence for the survival of Equus Sussemionus until the late Holocene. Elife 2022 May 11;11.
- Yuan JX, Hou XD, Barlow A, Preick M, Taron UH, Alberti F, Basler N, Deng T, Lai XL, Hofreiter M, Sheng GL. Molecular identification of late and terminal Pleistocene Equus ovodovi from northeastern China. PLoS One 2019;14(5):e0216883.
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