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Journal of equine veterinary science2023; 126; 104292; doi: 10.1016/j.jevs.2023.104292

Contribution of Hemogram Plan in the Horse’s Clinical Evaluation.

Abstract: The interpretation of the blood count is essential to help the equine clinician in the diagnosis, prognosis, patient management, and control of equine diseases. Hematologic alterations often reflect the condition of the individual or an overall response to a pathological situation. A thorough clinical examination of the patient is essential to correctly interpret the hematological results. The most common abnormalities in the erythrogram are mainly anemia and polycythemia. The frequent causes of anemia in horses are acute and chronic blood loss, hemolytic anemia, and anemia caused by chronic disease. Evaluation of leukogram, including a total white cell count, a differential cell count, absolute numbers of specific leukocytes can help identify abnormalities that may suggest specific diseases such as a viral or bacterial infection, inflammatory disorders or even a neoplastic process. The platelet count is most often used to monitor or diagnose conditions that cause too much bleeding related with thrombocytopenia; it can be due to multiple mechanisms such as reduction of thrombopoiesis (myeloptisis, myelofibrosis, myeloproliferative disease, and idiopathic medullary aplasias or due to the effect of mielosuppresive drugs), increased peripheral destruction of platelets (immune mediated thrombocytopenia), consumption (dissemined intravascular coagulation) sequestration of the spleen and loss of platelets by idiopathic origin.
Publication Date: 2023-03-22 PubMed ID: 36958411DOI: 10.1016/j.jevs.2023.104292Google Scholar: Lookup
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Summary

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The research article focuses on the importance of blood count interpretation in the clinical evaluation of horses for diagnosis, prognosis and management of diseases, with a keen attention on abnormalities related to erythrogram, leukogram and platelet count.

Importance of Hemogram in Equines

  • The paper begins by emphasizing on the need of interpreting blood count in equines for the purpose of diagnosing and managing diseases. It presents the blood count as a reflection of the health condition of the horse and emphasizes on the importance of a thorough clinical examination for an accurate interpretation of hematological results.

Erythrogram Abnormalities

  • Study mentions about the two common anomalies found in erythrogram – anemia and polycythemia.
  • It discusses the frequent causes of anemia in horses, which are mainly linked to acute and chronic blood loss, hemolytic anemia, and an in-borne chronic disease.

Leukogram Evaluation

  • The authors advocate for a comprehensive evaluation of the leukogram.
  • This evaluation extends to total white cell count, differential cell count, and the absolute numbers of specific leukocytes.
  • Such an in-depth analysis can help identify abnormalities that might indicate the presence of specific diseases such as viral or bacterial infections, inflammatory disorders, or even cancerous growths.

Platelet Count

  • The article lays special emphasis on the platelet count as a means to detect conditions fostering excessive bleeding related to thrombocytopenia.
  • The causes of such conditions are further divided into various categories which include reduction of thrombopoiesis due to myeloptisis, myelofibrosis, myeloproliferative disease, idiopathic medullary aplasias or the effect of medullary suppressive drugs, increased peripheral destruction of platelets due to immune mediated thrombocytopenia, consumption due to disseminated intravascular coagulation, spleen sequestration and loss of platelets due to an idiopathic cause.

Cite This Article

APA
Satué K, Fazio E, Gardón JC, Medica P. (2023). Contribution of Hemogram Plan in the Horse’s Clinical Evaluation. J Equine Vet Sci, 126, 104292. https://doi.org/10.1016/j.jevs.2023.104292

Publication

ISSN: 0737-0806
NlmUniqueID: 8216840
Country: United States
Language: English
Volume: 126
Pages: 104292
PII: S0737-0806(23)00082-5

Researcher Affiliations

Satué, Katiuska
  • Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, CEU-Cardenal Herrera University, Valencia, Spain. Electronic address: ksatue@uchceu.es.
Fazio, Esterina
  • Department of Veterinary Sciences, Veterinary Physiology Unit, Polo Universitario Annunziata, Messina, Italy.
Gardón, Juan Carlos
  • Department of Medicine and Animal Surgery, Catholic University of Valencia (San Vicente Mártir), Valencia, Spain.
Medica, Pietro
  • Department of Veterinary Sciences, Veterinary Physiology Unit, Polo Universitario Annunziata, Messina, Italy.

MeSH Terms

  • Horses
  • Animals
  • Blood Platelets
  • Thrombocytopenia / diagnosis
  • Thrombocytopenia / veterinary
  • Thrombocytopenia / etiology
  • Platelet Count / veterinary
  • Anemia / diagnosis
  • Anemia / veterinary
  • Anemia / complications
  • Horse Diseases / diagnosis

Citations

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