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Veterinary ophthalmology2024; 27(6); 549-557; doi: 10.1111/vop.13212

Diamond burr debridement of calcific band keratopathy in 24 eyes of 22 horses.

Abstract: To evaluate the safety and effectiveness of diamond burr debridement (DBD) for the treatment of calcific band keratopathy (CBK) in horses. Methods: Medical records from horses with CBK were reviewed over a period of 4 years. Diagnosis of CBK was based on slit-lamp examination findings, and DBD was performed on standing sedated horses. Follow-up was obtained by clinical reevaluation of the treated eyes or a telephone survey with the referring veterinarian. Results: Twenty-two horses of different ages (median: 11 years; range: 5-23) representing 24 CBK-affected eyes (14 left eyes and 10 right eyes) were included in the study. The patients had a medical history of chronic and recurrent uveitis, which required repeated long-term treatments with various combinations of ophthalmic corticosteroids. DBD alone cleared the cornea in 22 affected eyes (92%), but it was combined with blade scraping in two cases with thick calcium plaques. The postoperative medication included a topical antibiotic, atropine drops, and oral flunixin meglumine. Corneal healing was achieved in 21 eyes (87%), 5-21 days (median time 13 days) postoperatively. The three remaining horses were lost to follow-up. Recurrence occurred in 5 of the 21 (24%) reexamined eyes, 3-12.5 weeks (median 8 weeks) postoperatively, and required a second DBD. Four of the 21 eyes ended up being enucleated due to sequelae of uveitis. The main limitations of the study include those inherent to all retrospective clinical data collections. Conclusions: Mechanical DBD can readily and safely clear the cornea in horses with CBK, but recurrence of calcium deposition is possible.
Publication Date: 2024-03-26 PubMed ID: 38529825DOI: 10.1111/vop.13212Google Scholar: Lookup
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  • Journal Article

Summary

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The research paper examines the safety and success of diamond burr debridement (DBD), a procedure used to treat calcific band keratopathy (CBK), a form of eye disease, in horses.

Research Methodology

  • The researchers analyzed the medical records of horses diagnosed with CBK over a period of four years. The diagnosis of CBK was based on findings from a slit-lamp examination.
  • The DBD treatment was performed on standing, sedated horses.
  • Follow-up was conducted through a clinical reevaluation of the treated eyes or a telephone survey with the referring veterinarian.

Study Participants

  • The study consisted of 22 horses of varying ages, with a total of 24 CBK-affected eyes.
  • These horses had a history of chronic and recurrent uveitis, an inflammation of the eye, which previously required long-term, repeated treatments with a range of ophthalmic corticosteroids.

Execution and Results

  • DBD alone was successful in clearing the cornea in 22 of the affected eyes.
  • In two cases with particularly thick calcium plaques, DBD was combined with blade scraping to achieve success.
  • After the operation, horses were given topical antibiotics, atropine drops, and oral flunixin meglumine.
  • Corneal healing was achieved in 21 eyes within a span of 5-21 days post-operatively.
  • Three horses were lost to follow-up, and recurrence of the condition was observed in five out of the remaining 21 eyes between 3-12.5 weeks post-operatively, necessitating a second DBD procedure.
  • Unfortunately, four eyes had to be enucleated due to complications from uveitis.

Conclusion

  • Despite the limitations of the study, such as being a retrospective clinical data collection, the study concludes that mechanical DBD is a safe and successful treatment for clearing the cornea in horses with CBK.
  • However, the study notes that the calcium deposition can potentially recur post-treatment.

Cite This Article

APA
Jugant S, Regnier A, Douet JY. (2024). Diamond burr debridement of calcific band keratopathy in 24 eyes of 22 horses. Vet Ophthalmol, 27(6), 549-557. https://doi.org/10.1111/vop.13212

Publication

ISSN: 1463-5224
NlmUniqueID: 100887377
Country: England
Language: English
Volume: 27
Issue: 6
Pages: 549-557

Researcher Affiliations

Jugant, Sophie
  • OphtoVet-Méditerranée, Nîmes, France.
Regnier, Alain
  • CHUVAC, Université de Toulouse, ENVT, Toulouse, France.
Douet, Jean-Yves
  • CHUVAC, Université de Toulouse, ENVT, Toulouse, France.
  • IHAP, Université de Toulouse, INRAE, ENVT, Toulouse, France.

MeSH Terms

  • Animals
  • Horses
  • Horse Diseases / surgery
  • Debridement / veterinary
  • Debridement / instrumentation
  • Female
  • Male
  • Retrospective Studies
  • Calcinosis / veterinary
  • Calcinosis / surgery
  • Corneal Dystrophies, Hereditary / veterinary
  • Corneal Dystrophies, Hereditary / surgery
  • Corneal Diseases / veterinary
  • Corneal Diseases / surgery
  • Treatment Outcome

References

This article includes 28 references
  1. Rebhun WC. Corneal dystrophies and degeneration in horses.. Compend Contin Educ Vet 1992;14:945‐949.
  2. Rebhun WC, Murphy CJ, Hacker DV. Calcific band keratopathy in horses.. Compend Contin Educ Vet 1993;15:1402‐1409.
  3. Dubielzig RR, Ketring KL, McLellan GJ, Albert DM. Diseases of the cornea and sclera.. In: Dubielzig RR, Ketring K, McLellan GJ, Albert DM, eds. Veterinary Ocular Pathology a Comparative Review; W.B. Saunders, Edinburgh, 2010:202‐243.
  4. Brooks DE. Equine stromal and endothelial keratopathies: medical management of stromal abscesses, eosinophilic keratitis, calcific band keratopathy, striate band opacities, and endotheliitis in the horse.. Clin Tech Equine Pract 2005;4:21‐28.
  5. O'Connor GR. Calcific band keratopathy.. Trans Am Ophthalmol Soc 1972;70:58‐81.
  6. Brooks DE, Matthews A, Clode AB. Diseases of the cornea.. In: Gilger BC, ed. Equine Ophthalmology. 3rd ed. John Wiley & Sons, Inc., 2017:252‐368.
  7. Jhanji V, Rapuano CJ, Vajpayee RB. Corneal calcific band keratopathy.. Curr Opin Ophthalmol 2011;22:283‐289.
  8. Bernauer W, Thiel MA, Kurrer M. Corneal calcification following intensified treatment with sodium hyaluronate artificial tears.. Br J Ophthalmol 2006;90:285‐288.
  9. Moisseiev E, Gal A, Addadi L, Caspi D, Shemesh G, Michaeli A. Acute calcific band keratopathy: case report and literature review.. J Cataract Refract Surg 2013;39:292‐294.
  10. Brooks DE. Clinical commentary calcium degeneration and ocular surface failure in the horse.. Equine Vet Educ 2012;24:8‐11.
  11. Gilger BC, Holligsworth SR. Diseases of the uvea, uveitis, and recurrent uveitis.. In: Gilger BC, ed. Equine Ophthalmology. 3rd ed. John Wiley & Sons, Inc., 2017:369‐415.
  12. Berryhill EH, Thomasy SM, Kass PH. Comparison of corneal degeneration and calcific band keratopathy from 2000 to 2013 in 69 horses.. Vet Ophthalmol 2017;20:16‐26.
  13. Al‐Hity A, Ramaesh K, Lockington D. EDTA chelation for symptomatic band keratopathy: results and recurrence.. Eye 2018;32:26‐31.
  14. Nevile JC, Hurn SD, Turner AG, Morton J. Diamond burr debridement of 34 canine corneas with presumed corneal calcareous degeneration.. Vet Ophthalmol 2016;19:305‐312.
  15. Anastassiadis Z, Read RA, Bayley KD. Topical ethylenediaminetetraacetic acid (EDTA) administration following corneal diamond burr keratotomy for calcareous corneal degeneration in canines.. Vet Ophthalmol 2022;25:225‐231.
  16. Bee CR, Koenig LR, Hwang ES, Koenig SB. Removal of calcific band keratopathy without ethylenediaminetetraacetic acid (EDTA) in eyes with limited visual potential.. Clin Ophthalmol 2018;12:1895‐1899.
  17. Lassaline‐Utter M, Cutler TJ, Michau TM, Nunnery CM. Treatment of nonhealing corneal ulcers in 60 horses with diamond burr debridement (2010–2013).. Vet Ophthalmol 2014;17(Suppl 1):76‐81.
  18. Najjar DM, Cohen EJ, Rapuano CJ, Laibson PR. EDTA chelation for calcific band keratopathy: results and long‐term follow‐up.. Am J Ophthalmol 2004;137:1056‐1064.
  19. O'Brart DPS, Gartry DS, Lohmann CP, Patmore AL, Kerr Muir MG, Marshall J. Treatment of band keratopathy by excimer laser phototherapeutic keratectomy: surgical technique and long term follow up.. Br J Ophthalmol 1993;77:702‐708.
  20. Doughman DJ, Olson GA, Nolan S, Hajny BS. Experimental band keratopathy.. Arch Ophthalmol 1969;81:264‐271.
  21. Taravella MJ, Stulting D, Mader TH, Weisenthal RW, Forstot L, Underwood LD. Calcific band keratopathy associated with the use of topical steroid phosphate preparations.. Arch Ophthalmol 1994;112:608‐613.
  22. Popiela MZ, Hawksworth N. Corneal calcification and phosphates: do you need to prescribe phosphate free?. J Ocul Pharmacol Ther 2014;30:800‐802.
  23. Plummer CE. Equine ophthalmology.. In: Gelatt KN, Ben‐Shlomo G, Gilger BC, Hendrix DVH, Kern TJ, Plummer CE, eds. Veterinary Ophthalmology, volume II. 6th ed. Wiley Blackwell; 2021:1841‐1982.
  24. Bokosky JE, Meyer RF, Sugar A. Surgical treatment of calcific band keratopathy.. Ophthalmic Surg 1985;16:645‐647.
  25. McGrath L, Lee GA. Corneal epithelial debridement for diagnosis and therapy of ocular surface disease.. Clin Exp Optom 2015;98:155‐159.
  26. Michau TM, Schwabenton B, Davidson MG, Gilger BC. Superficial, nonhealing corneal ulcers in horses: 23 cases (1989–2003).. Vet Ophthalmol 2003;6:291‐297.
  27. Kaz Soong H, Farjo Q, Meyer RF, Sugar A. Diamond burr superficial keratectomy for recurrent corneal erosions.. Br J Ophthalmol 2002;86:296‐298.
  28. Gerding JC, Gilger BC. Prognosis and impact of equine recurrent uveitis.. Equine Vet J 2016;48:290‐298.