Effect on fertility of human chorionic gonadotrophin and uterine lavage with oxytocin performed after mating in Arabian barren mares.

This research study aimed to determine the effects of human chorionic gonadotrophin (hCG) injections and uterine lavage with oxytocin on the fertility of Arabian barren mares. The outcome revealed that mares injected with hCG immediately after mating, particularly when combined with a uterine lavage and oxytocin, had significantly improved fertility rates.

Objective and Method

• The aim of this study was to gauge the positive effect of injecting hCG immediately after mating in Arabian barren mares who were also given a uterine lavage treatment and oxytocin.
• The tested mares were subjected to detailed medical evaluations, such as rectal palpation, vaginoscopy, and cytological tests.
• The 36 mares were randomly divided into four separate groups for different treatments after mating.

Setting up the Groups

• Mares in group one were given 3,000 IU of hCG right after breeding. They were also given a uterine lavage that contained 1L of N-Saline, 4 million IU of crystalline penicillin and 4g of streptomycin sulphate. This was performed 4 hours post-breeding. These mares also received two injections of 40 IU IM oxytocin 6 hours after mating.
• Group two mares received the same treatment as the first group, excluding the hCG injection.
• Group three mares were only subjected to a uterine lavage treatment.
• The control group (group four) was not given any treatment.

Results Of The Research

• The clinical examination revealed that 69.4% of the barren mares had severe endometritis, while 30.6% had a moderate form. A significant (p<0.01) increase in lymphocytes was observed in the barren mares involved in the study.
• The pregnancy rate was significantly higher (P<0.01) in barren mares that were injected with hCG right after mating, with the addition of the uterine lavage and oxytocin treatment.
• No significant differences were found between the mares who only received the uterine lavage and those who also got oxytocin.
• In conclusion, the hCG injection given immediately after mating, along with a post-mating uterine lavage with antibiotics and two 40 IU IM oxytocin injections given two hours apart after six hours of mating, significantly improved the fertility rates of the Arabian barren mares.