Effect on fertility of human chorionic gonadotrophin and uterine lavage with oxytocin performed after mating in Arabian barren mares.
Abstract: The objective of the present study was to evaluate the beneficial effect of hCG injected immediately after mating in Arabian barren mares treated with uterine lavage and oxytocin. Arabian barren mares (n=36) with PMIE were subjected to detailed clinical examinations including palpation per rectum, vaginoscopy, and cytological examination. After mating the 36 mares were randomly divided into four groups. The mares in group 1 (n=10) were immediately after breeding injected with hCG 3,000 IU IM. Uterine lavage with 1L of N-saline containing 4 million IU of crystalline penicillin and 4 g of streptomycin sulphate was performed 4h after breeding. Then mares received two injections of oxytocin 40 IU IM 2h apart after 6h of mating. Mares in group 2 (n=10) treated with uterine lavage and oxytocin as group 1. While mares in group 3 (n=10) received uterine lavage only. A control group (n=6) as group 4 did not received any treatment. The results of clinical examination indicated that 69.4% of PMIE mares were harboring severe endometritis and 30.6% with a moderate form of endometritis. Significant (P<0.01) increase in lymphocytes were founded in barren mares included in this study. Higher pregnancy rate (P<0.01) was founded in Arabian barren mares 80% injected with hCG immediately after breeding and uterine lavage and oxytocin. No significant difference was found in mares received uterine lavage and oxytocin and uterine lavage only. In a conclusion, administration of hCG immediately after mating and intrauterine lavage containing antibiotics performed 4h and two injections of oxytocin 40 IU IM 2h apart after 6h of mating had improved fertility of Arabian barren mares.
Publication Date: 2007-05-18 PubMed ID: 17681436DOI: 10.1016/j.anireprosci.2007.05.010Google Scholar: Lookup
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- Journal Article
- Randomized Controlled Trial
Summary
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This research study aimed to determine the effects of human chorionic gonadotrophin (hCG) injections and uterine lavage with oxytocin on the fertility of Arabian barren mares. The outcome revealed that mares injected with hCG immediately after mating, particularly when combined with a uterine lavage and oxytocin, had significantly improved fertility rates.
Objective and Method
- The aim of this study was to gauge the positive effect of injecting hCG immediately after mating in Arabian barren mares who were also given a uterine lavage treatment and oxytocin.
- The tested mares were subjected to detailed medical evaluations, such as rectal palpation, vaginoscopy, and cytological tests.
- The 36 mares were randomly divided into four separate groups for different treatments after mating.
Setting up the Groups
- Mares in group one were given 3,000 IU of hCG right after breeding. They were also given a uterine lavage that contained 1L of N-Saline, 4 million IU of crystalline penicillin and 4g of streptomycin sulphate. This was performed 4 hours post-breeding. These mares also received two injections of 40 IU IM oxytocin 6 hours after mating.
- Group two mares received the same treatment as the first group, excluding the hCG injection.
- Group three mares were only subjected to a uterine lavage treatment.
- The control group (group four) was not given any treatment.
Results Of The Research
- The clinical examination revealed that 69.4% of the barren mares had severe endometritis, while 30.6% had a moderate form. A significant (p<0.01) increase in lymphocytes was observed in the barren mares involved in the study.
- The pregnancy rate was significantly higher (P<0.01) in barren mares that were injected with hCG right after mating, with the addition of the uterine lavage and oxytocin treatment.
- No significant differences were found between the mares who only received the uterine lavage and those who also got oxytocin.
- In conclusion, the hCG injection given immediately after mating, along with a post-mating uterine lavage with antibiotics and two 40 IU IM oxytocin injections given two hours apart after six hours of mating, significantly improved the fertility rates of the Arabian barren mares.
Cite This Article
APA
Azawi OI.
(2007).
Effect on fertility of human chorionic gonadotrophin and uterine lavage with oxytocin performed after mating in Arabian barren mares.
Anim Reprod Sci, 106(3-4), 345-351.
https://doi.org/10.1016/j.anireprosci.2007.05.010 Publication
Researcher Affiliations
- Department of Surgery and Obstetrics, College of Veterinary, Medicine, University of Mosul, Mosul, Iraq. azawihh@yahoo.com
MeSH Terms
- Animals
- Chorionic Gonadotropin / pharmacology
- Chorionic Gonadotropin / therapeutic use
- Endometritis / etiology
- Endometritis / prevention & control
- Female
- Fertility / drug effects
- Horses
- Oxytocin / administration & dosage
- Oxytocin / pharmacology
- Pregnancy
- Pregnancy Rate
- Pregnancy, Animal / drug effects
- Sexual Behavior, Animal / drug effects
- Sexual Behavior, Animal / physiology
- Uterus / drug effects
- Vaginal Douching / methods
- Vaginal Douching / veterinary
Citations
This article has been cited 1 times.- Karam KM, Alebady AS, Alhilfi HO, Al-Delemi DH. Comparative study utilizing different post-breeding treatment regimens in cyclic Arabian mares. Vet World 2021 Nov;14(11):2863-2868.
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