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Home / Equine Research Bank / Animals (Basel) / Epidemiology and Control of Rabies in Cattle and Equines in ...
Animals : an open access journal from MDPI2023; 13(18); doi: 10.3390/ani13182974

Epidemiology and Control of Rabies in Cattle and Equines in Rondônia State, a Brazilian’s Legal Amazon Area.

Abstract: Rabies is a fatal neglected tropical zoonosis, and its significance for domestic herbivores in the rural cycle is probably associated with rainforest deforestation, livestock, and agricultural expansion. This epidemiological survey aimed to study the occurrence of rabies in bovines and equines in the state of Rondônia, located in the Brazilian's Legal Amazon, between the years 2002 and 2021, correlating these findings with the prophylactic strategies adopted by the local sanitary agency for rabies control. During this period, 201 cases were observed in bovines and 23 in equines. A downward trend in rabies incidence was observed for both domestic herbivores. Rabies did not show a higher occurrence in any specific time of the year, and epidemic periods varied during some years for bovines and equines. Using the Generalized estimating equations (GEE) method, a multiple model approach was obtained with the explanatory variables significantly associated with the decrease in rabies incidence in cattle and horses during the study period: the ratio of treated bats and ratio of vaccine doses sold. Furthermore, the ratio of printed educative material was positively associated with rabies incidence. Despite a decreasing trend in rabies occurrences in this Amazon rainforest area, likely due to the actions taken by the animal sanitary agency, rabies remains endemic and requires monitoring, as well as prophylactic strategies to control this disease.
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Publication Date: 2023-09-20 PubMed ID: 37760375PubMed Central: PMC10526067DOI: 10.3390/ani13182974Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article investigates trends in the occurrence of rabies in bovines (cattle) and equines (horses) in the Brazilian state of Rondônia from 2002 to 2021 and analyzes how preventative strategies from local sanitary agencies correlate with these trends.

Overview of the Study

The study focuses on the epidemiology of rabies in Rondônia, a state in Brazil’s Legal Amazon area. The researchers collected data on rabies occurrences in bovines and equines over nearly a two-decade span, from 2002 to 2021. They identified:

  • 201 cases of rabies in bovines
  • 23 cases of rabies in equines

During this time, they noted a decrease in the overall incidence of rabies in both species, without any specific seasonal peaks.

Statistical Analysis of Data

The researchers utilized a statistical analytical method known as the Generalized Estimating Equations (GEE) method. This method enabled them to create a multiple model approach that confirmed the factors significantly associated with the decrease in rabies incidents in the population of bovines and equines.

Associative Factors

Through their analytical model, the researchers identified two main factors that were significantly associated with the observed decrease in rabies incidence:

  • The ratio of treated bats: This suggests that interventions aimed at controlling bat populations, which are common carriers of the rabies virus, contributed to the decrease in rabies incidence.
  • The ratio of vaccine doses sold: The increased availability and administration of vaccines also contributed to reducing rabies cases within the studied populations.

Interestingly, the researchers also found a positive association between the incidence of rabies and the ratio of printed educative material. This finding implies that while awareness campaigns are crucial, they may not be entirely sufficient for disease control.

Concluding Remarks

Despite the noted decrease in the incidence of rabies in bovines and equines in Rondônia, the study concludes that rabies remains endemic in the area. Continued monitoring and preventative efforts are required to further control the disease. This implies a need for sustained and comprehensive efforts to administer vaccines and control bat populations in the region.

Cite This Article

APA
Sodré DNA, Rossi GAM, Mathias LA, de Andrade Belo MA. (2023). Epidemiology and Control of Rabies in Cattle and Equines in Rondônia State, a Brazilian’s Legal Amazon Area. Animals (Basel), 13(18). https://doi.org/10.3390/ani13182974

Publication

Animals : an open access journal from MDPI
ISSN: 2076-2615
NlmUniqueID: 101635614
Country: Switzerland
Language: English
Volume: 13
Issue: 18

Researcher Affiliations

Sodré, Débora Naihane Alves
  • IDARON-Agency of Agrosilvopastoral Sanitary Defense of Rondônia State, Cacoal 76964-062, RO, Brazil.
  • Department of Veterinary Medicine, Brazil University (UB), Descalvado 13690-000, SP, Brazil.
Rossi, Gabriel Augusto Marques
  • Department of Veterinary Medicine, Vila Velha University (UVV), Vila Velha 29102-920, ES, Brazil.
Mathias, Luis Antonio
  • Department of Pathology, Reproduction and One Health, São Paulo State University (UNESP), Jaboticabal 14884-900, SP, Brazil.
de Andrade Belo, Marco Antonio
  • Department of Veterinary Medicine, Brazil University (UB), Descalvado 13690-000, SP, Brazil.

Conflict of Interest Statement

The authors declare no conflict of interest.

References

This article includes 40 references
  1. OIE World Organization for Animal Health. OIE Listed. Rabies. [(accessed on 19 May 2022)]. Available online: https://www.oie.int/en/disease/rabies/
  2. WHO World Health Organization. Factsheets. Rabies. [(accessed on 7 July 2023)]. Available online: https://www.who.int/news-room/fact-sheets/detail/rabies.
  3. Ministry of Health. Raiva: O Que é, Causas, Sintomas, Tratamento, Diagnóstico e Prevenção. Ministério da Saúde; Brasília, Brazil: 2020.
  4. Benavides JA, Megid J, Campos A, Hampson K. Using surveillance of animals bite patients to decipher potential risks of rabies exposure from domestic animals and wildlife in Brazil. Front. Public Health 2020;8:318.
    doi: 10.3389/fpubh.2020.00318pmc: PMC7396646pubmed: 32850575google scholar: lookup
  5. Pimentel MFA, Nassarden SM, Cândido SL, Dutra V, Nakazato L. Genotyping of rabies positive samples isolated from animals in Mato Grosso and Rondonia—Brazil. Infect. Genet. Evol. 2022;103:105336.
    doi: 10.1016/j.meegid.2022.105336pubmed: 35817398google scholar: lookup
  6. Kobayashi Y, Sato G, Mochizuki N, Hirano S, Itou T, Carvalho AAB, Albas A, Santos HP, Ito FH, Sakai T. Molecular and geographic analyses of vampire bat-transmitted cattle rabies in central Brazil. BMC Vet. Res. 2008;4:44.
    doi: 10.1186/1746-6148-4-44pmc: PMC2613875pubmed: 18983685google scholar: lookup
  7. Horta MA, Ledesma LA, Moura WC, Lemos ERS. From dogs to bats: Concerns regarding vampire bat-borne rabies in Brazil. PLoS Negl. Trop. Dis. 2022;16:e0010160.
    doi: 10.1371/journal.pntd.0010160pmc: PMC8893325pubmed: 35239665google scholar: lookup
  8. Ribeiro J, Vieira RGV, Martins CM, Ferreira F, Araujo JP, Ullmann LS, Santos AP, Biondo AW. Spatial distribution of bat shelters and livestock rabies in Sothern Brazil. Vector Born Zoonotic Dis. 2021;21:785–795.
    doi: 10.1089/vbz.2020.2730pubmed: 34661486google scholar: lookup
  9. Mello AKM, Brumatti RC, Neves DA, Alcântara LOB, Araújo FS, Gaspar AO, Lemos RAA. Bovine rabies: Economic loss and its mitigation through antirabies vaccination. Pesq. Vet. Bras. 2019;39:179–185.
    doi: 10.1590/1678-5150-pvb-6201google scholar: lookup
  10. Andrade EA, Monteiro FDO, Solorio MR, Raia VA, Xavier DA, Colino E, Guimarães RJPS, Abel I. Livestock rabies in Pará state, Brazil: A descriptive study (2004 to 2013). Pesq. Vet. Bras. 2020;40:234–241.
    doi: 10.1590/1678-5150-pvb-6307google scholar: lookup
  11. Oliveira FAS, Castro RJS, Oliveira JF, Barreto FM, Farias MPO, Marinho GLO, Soares MJS, Silva-Júnior A, Schwarz DGG. Geographical and temporal spread of equine rabies in Brazil. Acta Trop. 2022;227:106302.
    doi: 10.1016/j.actatropica.2022.106302pubmed: 34990596google scholar: lookup
  12. Ministry of Agriculture, Food and Supply Chain, Brazil. Herbivores Rabies Control Program. Ministry of Agriculture, Food and Supply Chain, Brazil; 2009.
  13. Viana M, Benavides JA, Broos A, Loayza DI, Niño R, Bone J, Filipe AS, Orton R, Bazan WV, Streicker DG. Effects of culling vampire bats on the spatial spread and spillover of rabies virus. Sci. Adv. 2023;9:10.
    doi: 10.1126/sciadv.add7437pmc: PMC10005164pubmed: 36897949google scholar: lookup
  14. Zhao L, Chen T, Miao F, Li J, Du H, Zhao J. Bat lyssavirus should be further monitored in Rondônia state, Brazil. Rev. Soc. Bras. Med. Trop. 2020;53:e20190420.
    doi: 10.1590/0037-8682-0420-2019pmc: PMC7182290pubmed: 32321090google scholar: lookup
  15. EMATER. AGRO—Anuário 2019 E 2020. 2020 Número 01—Dezembro/2020.
  16. Petrie A, Watson P. Statistics for Veterinary and Animal Science. 3rd ed. Wiley-Blackwell; Hoboken, NJ, USA: 2013. 391p.
  17. Mohr F. Prais-Winsten Estimator for AR(1) Serial Correlation. 2021.
  18. Antunes JLF, Waldman EA. Trends and spatial distribution of deaths of children aged 12–60 months in São Paulo, Brazil, 1980–1998. Bull. World Health Organ. 2002;80:391–398.
    pmc: PMC2567796pubmed: 12077615
  19. Maletta CHM. Epidemiologia e Saúde Pública. 3rd ed. Coopermed.; Camden, NJ, USA: 2014. 322p.
  20. Dohoo IR, Martin SW, Henrik S. Veterinary Epidemiological Research. 2nd ed. VER Inc.; Glendale, CA, USA: 2009.
  21. Dognani R, Pierre EJ, Silva MCP, Patrício MAC, Costa SC, Prado JR, Lisbôa JAN. Epidemiologia descritiva da raiva dos herbívoros notificados no estado do Paraná entre 1977 e 2012. Pesqui. Vet. Bras. 2016;36:1145–1154.
    doi: 10.1590/s0100-736x2016001200001google scholar: lookup
  22. Matta GCA, Nociti AAB, Carvalho AAB, Nociti RP, Samara SI. Caracterização epidemiológica da raiva bovina no estado de Mato Grosso, Brasil, no período de 1996 a 2006. Arq. Inst. Biol. 2010;77:601–607.
    doi: 10.1590/1808-1657v77p6012010google scholar: lookup
  23. Silva GCP, Santos RF, Rocha SM, Reis VGL, Santos GR, Godoy HP, Mathias LA, Nociti DLP. Perfil da ocorrência de raiva animal em diferentes espécies no estado de Mato Grosso, Brasil, de 2002 a 2011. Rev. Bras. Cienc. Vet. 2017;24:151–156.
    doi: 10.4322/rbcv.2017.029google scholar: lookup
  24. de Almeida GL, Cargnelutti JF, Ries AS, Ferreira JC, Rosa JCA, Batista HBCR, Flores EF, Weiblen R. Sequence analysis of nucleoprotein gene reveals the co-circulation of lineages and sublineages of rabies virus in herbivorous in Rio Grande do Sul state, Brazil. Braz. J. Microbiol. 2020;51:837–846.
    doi: 10.1007/s42770-020-00226-zpmc: PMC7203323pubmed: 31953649google scholar: lookup
  25. Casseb LMN, Barbosa TFS, Pereira AS, Vieira CA, Medeiros DBA, Vasconcelos PFC, da Rosa EST, Casseb AR. Prevalência de raiva animal em amostras procedentes da região Norte do Brasil, diagnosticadas no Instituto Evandro Chagas no período de 2000 a 2004. Rev. Ciênc. Agrár. 2006;46:261–274.
  26. Santos AJF, Ferreira JM, Baptista F, Alexandrino B, Silva MAG, Gomes JEC, Veloso Júnior JP, Tavares RM, Almeida KS. Statistical analysis between 2006 and 2019 and forecast of rabies in cattle from 2020 to 2022 in Tocantins State (Brazil),by using the R Studio software. Epidemiol. Infect. 2022;150:e82.
    doi: 10.1017/S0950268822000553pmc: PMC9044522pubmed: 35346409google scholar: lookup
  27. Silva LP, Pontes AN, Bichara CNC. Raiva bovina na mesorregião nordeste do estado do Pará: Uma abordagem agroambiental. Rev. Ibero Am. Cienc. Ambient. 2021;12:139–152.
    doi: 10.6008/CBPC2179-6858.2021.001.0012google scholar: lookup
  28. Gomes MN, Monteiro AMV, Lewis N, Gonçalves CA, Filho VSN. Landscape risk factors for attacks of vampire bats on cattle in Sao Paulo, Brazil. Prev. Vet. Med. 2010;93:139–146.
    doi: 10.1016/j.prevetmed.2009.10.006pubmed: 20004487google scholar: lookup
  29. Santos GR. Caracterização Epidemiológica e Molecular da Raiva em Bovinos no Estado de Pernambuco, Brasil. Ph.D. Thesis. São Paulo State University; Sao Paulo, Brazil: 2016.
  30. Santos BL, Bruhn FRP, Coelho ACB, Estima-Silva P, Echenique JV, Sallis ESV, Schild AL. Epidemiological study of rabies in cattle in southern Brazil: Spatial and temporal distribution from 2008 to 2017. Pesqui. Vet. Bras. 2019;39:460–468.
    doi: 10.1590/1678-6160-pvb-6088google scholar: lookup
  31. Ribas NLS, Carvalho RS, Santos AC, Valençoela RA, Gouveia AF, Castro MB, Mori AE, Lemos RAA. Doenças do sistema nervoso de bovinos no Mato Grosso do Sul: 1082 casos. Pesq. Vet. Bras. 2013;33:1183–1194.
    doi: 10.1590/S0100-736X2013001000003google scholar: lookup
  32. Menezes FL, Silva JA, Moreira EC, Meneses JNC, Magalhães DF, Barbosa AD, Oliveira CSF. Distribuição espaço-temporal da raiva bovina em Minas Gerais. Arq. Bras. Med. Vet. Zootec. 2008;60:566–573.
    doi: 10.1590/S0102-09352008000300007google scholar: lookup
  33. Mantovan KB, Menozzi BD, Paiz LM, Sevá AP, Brandão PE, Langoni H. Geographic Distribution of Common Vampire Bat Desmodus rotundus (Chiroptera: Phyllostomidae) Shelters: Implications for the Spread of Rabies Virus to Cattle in Southeastern Brazil. Pathogens 2022;11:942.
    doi: 10.3390/pathogens11080942pmc: PMC9412479pubmed: 36015061google scholar: lookup
  34. Mendes P, Srbek-Araujo AC. Effects of land-use changes on Brazilian bats: A review of current knowledge. Mammal Rev. 2021;51:127–142.
    doi: 10.1111/mam.12227google scholar: lookup
  35. Gnocchi AP, Srbek-Araujo AC. Common Vampire Bat (Desmodus rotundus) feeding on Lowland Tapir (Tapirus terrestris) in an Atlantic Forest remnant in southeastern Brazil. Biota Neotrop. 2017;17:e20170326.
    doi: 10.1590/1676-0611-bn-2017-0326google scholar: lookup
  36. Duarte NFH, Alencar CH, Cavalcante KKS, Correia FGS, Phyllis CR, Araujo DB, Favoretto SR, Heukelbach J. Increased detection of rabis virus in bats in Ceará State (Northeast Brazil) after implementation of a passive surveillance program. Zoonoses Public Health 2019;67:186–192.
    doi: 10.1111/zph.12670pubmed: 31797575google scholar: lookup
  37. Johnson N, Aréchiga-Ceballos N, Aguilar-Seiten A. Vampire bat rabies: Epidemiology and control. Viruses 2014;6:1911–1928.
    doi: 10.3390/v6051911pmc: PMC4036541pubmed: 24784570google scholar: lookup
  38. Griffiths ME, Meza DK, Haydon DT, Streicker DG. Inferring the disruption of rabies circulation in vampire bat populations using a betaherpesvirus-vectored transmissible vaccine. Proc. Natl. Acad. Sci. USA 2023;120:e2216667120.
    doi: 10.1073/pnas.2216667120pmc: PMC10089182pubmed: 36877838google scholar: lookup
  39. Pan American Health Organization (PAHO). Regional Program for the Prevention and Control of Rabies Transmitted by the Hematophagous Bat (D. rotundus) to Susceptible Livestock in the Americas. Pan American Health Organization (PAHO); 2021.
  40. Rinchen S, Tenzin T, Hall D, van der Meer F, Sharma B, Dukpa K, Cork S. A community-based knowledge, attitude, and practice survey of rabies among cattle owners in selected areas of Buthan. PLoS Neglec. Trop. Dis. 2019;13:e0007305.
    doi: 10.1371/journal.pntd.0007305pmc: PMC6459539pubmed: 30933984google scholar: lookup
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