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Viruses2019; 11(9); 851; doi: 10.3390/v11090851

Equid alphaherpesvirus 1 from Italian Horses: Evaluation of the Variability of the ORF30, ORF33, ORF34 and ORF68 Genes.

Abstract: This study investigates the genetic variability of the equid alphaherpesvirus type 1 (EHV-1), a virus in horses, by evaluating four specific genes (ORF30, ORF33, ORF34, and ORF68) in Italian horse […]
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Publication Date: 2019-09-13 PubMed ID: 31540321PubMed Central: PMC6784080DOI: 10.3390/v11090851Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study investigates the genetic variability of the equid alphaherpesvirus type 1 (EHV-1), a virus in horses, by evaluating four specific genes (ORF30, ORF33, ORF34, and ORF68) in Italian horse populations.

Virus and Genes Studied

  • The research explores the equid alphaherpesvirus type 1 (EHV-1), a virus that infects horses and can cause various health problems including respiratory disease, abortion and a neurologic disease.
  • The focus of this study is on the variability in four genes of EHV-1: ORF30, ORF33, ORF34, and ORF68. These genes were selected because variants in these genes have been found to affect the severity and type of disease caused by EHV-1.

Methodology

  • The researchers collected samples from Italian horses infected with EHV-1.
  • They carried out sequence analysis on the genes ORF30, ORF33, ORF34, and ORF68 in these virus samples.
  • Next, they compared the sequences of these genes to those of known EHV-1 viruses to identify any mutations or variants.

Results and Implications

  • The exact results of the analysis would depend on the data discovered, which is not given in this abstract. However, the aim was to characterize the variability in these crucial EHV-1 genes in Italian horses.
  • Such information could be important for understanding the behavior of EHV-1 in different horse populations and could possibly lead to the development of improved diagnostic tests or vaccines. It could also play a fundamental role in designing and implementing targeted measures for the control and prevention of diseases caused by this virus in horses.

Cite This Article

APA
Preziuso S, Sgorbini M, Marmorini P, Cuteri V. (2019). Equid alphaherpesvirus 1 from Italian Horses: Evaluation of the Variability of the ORF30, ORF33, ORF34 and ORF68 Genes. Viruses, 11(9), 851. https://doi.org/10.3390/v11090851

Publication

Viruses
ISSN: 1999-4915
NlmUniqueID: 101509722
Country: Switzerland
Language: English
Volume: 11
Issue: 9
PII: 851

Researcher Affiliations

Preziuso, Silvia
  • School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica (MC), Italy. silvia.preziuso@unicam.it.
Sgorbini, Micaela
  • Department of Veterinary Sciences, University of Pisa, San Piero a Grado, 56122 Pisa, Italy. micaela.sgorbini@unipi.it.
Marmorini, Paola
  • Private Practitioner, 52100 Arezzo, Italy. ninnaro@tiscali.it.
Cuteri, Vincenzo
  • School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica (MC), Italy. vincenzo.cuteri@unicam.it.

MeSH Terms

  • Animals
  • DNA, Viral / genetics
  • Databases, Nucleic Acid
  • Genetic Variation
  • Genotype
  • Herpesviridae Infections / veterinary
  • Herpesvirus 1, Equid / classification
  • Herpesvirus 1, Equid / genetics
  • Horse Diseases / virology
  • Horses / virology
  • Italy
  • Open Reading Frames
  • Polymorphism, Single Nucleotide
  • Sequence Analysis, DNA

Conflict of Interest Statement

The authors declare no conflict of interest.

References

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Citations

This article has been cited 7 times.
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