Evaluation of a continuous glucose monitoring system for use in dogs, cats, and horses.
Abstract: To evaluate a continuous glucose monitoring system (CGMS) for use in dogs, cats, and horses. Methods: Prospective clinical study. Animals-7 horses, 3 cats, and 4 dogs that were clinically normal and 1 horse, 2 cats, and 3 dogs with diabetes mellitus. Methods: Interstitial glucose concentrations were monitored and recorded every 5 minutes by use of a CGMS. Interstitial glucose concentrations were compared with whole blood glucose concentrations as determined by a point-of-care glucose meter. Interstitial glucose concentrations were also monitored in 2 clinically normal horses after oral and i.v. administration of glucose. Results: There was a positive correlation between interstitial and whole blood glucose concentrations for clinically normal dogs, cats, and horses and those with diabetes mellitus. Events such as feeding, glucose or insulin administration, restraint, and transport to the clinic were recorded by the owner or clinician and could be identified on the graph and associated with time of occurrence. Conclusions: Our data indicate that use of CGMS is valid for dogs, cats, and horses. This system alleviated the need for multiple blood samples and the stress associated with obtaining those samples. Because hospitalization was not required, information obtained from the CGMS provided a more accurate assessment of the animal's glucose concentrations for an extended period, compared with measurement of blood glucose concentrations. Use of the CGMS will promote the diagnostic and research potential of serial glucose monitoring.
Publication Date: 2003-10-14 PubMed ID: 14552487DOI: 10.2460/javma.2003.223.987Google Scholar: Lookup
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- Evaluation Study
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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This research paper evaluated a continuous glucose monitoring system (CGMS) to monitor glucose levels in dogs, cats, and horses, both those with normal health conditions and those diagnosed with diabetes mellitus. The study concluded that the CGMS is a valid tool for glucose monitoring in these animals, reducing the stress of multiple blood samples and eliminating the need for hospitalization.
Methods and Animal Subjects
- The research was carried out in the form of a prospective clinical study, which means it was designed and carried out to test a hypothesis about a specific health problem.
- The animal subjects used for the study consisted of 7 horses, 3 cats, and 4 dogs that were clinically normal as well as 1 horse, 2 cats, and 3 dogs that had been diagnosed with diabetes mellitus.
Glucose Monitoring and Comparison
- The continuous glucose monitoring system (CGMS) was used to monitor and record interstitial glucose concentrations (that is, the concentration of glucose in the fluid between cells) every 5 minutes.
- The results from the CGMS were then compared with whole blood glucose concentrations, as determined by a point-of-care glucose meter (a device that allows for immediate results and treatment plans).
- In addition, interstitial glucose concentrations were also monitored in two clinically normal horses following oral and intravenous administration of glucose.
Results and Findings
- The study found that there was a positive correlation between interstitial and whole blood glucose concentrations in both healthy animals and animals with diabetes mellitus.
- Significant events such as feeding, insulin administration, restraint, and transport to the clinic were all recorded and could be traced on a graph, helping to contextualize fluctuations in glucose levels.
Conclusions
- Based on the study findings, the authors conclude that the CGMS is a valid and useful tool for glucose monitoring in dogs, cats, and horses.
- Using this system eliminated the stress associated with drawing multiple blood samples and the need for hospitalization, both of which can have a significant impact on glucose levels.
- The CGMS gave a clearer and more accurate picture of the animal’s glucose concentration over an extended period, improving upon the traditional method of measuring blood glucose concentrations at singular points in time.
- The researchers also suggested that the use of CGMS can enhance diagnostic and research possibilities in the field of serial glucose monitoring.
Cite This Article
APA
Wiedmeyer CE, Johnson PJ, Cohn LA, Meadows RL.
(2003).
Evaluation of a continuous glucose monitoring system for use in dogs, cats, and horses.
J Am Vet Med Assoc, 223(7), 987-992.
https://doi.org/10.2460/javma.2003.223.987 Publication
Researcher Affiliations
- Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA.
MeSH Terms
- Animals
- Blood Glucose / analysis
- Cat Diseases / blood
- Cat Diseases / diagnosis
- Cats
- Diabetes Mellitus / blood
- Diabetes Mellitus / diagnosis
- Diabetes Mellitus / veterinary
- Dog Diseases / blood
- Dog Diseases / diagnosis
- Dogs
- Horse Diseases / blood
- Horse Diseases / diagnosis
- Horses
- Monitoring, Physiologic / instrumentation
- Monitoring, Physiologic / veterinary
- Prospective Studies
- Sensitivity and Specificity
Citations
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