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Home / Equine Research Bank / Parasit Vectors / Faecal Cyathostomin Egg Count distribution and efficacy of a...
Parasites & vectors2009; 2 Suppl 2(Suppl 2); S4; doi: 10.1186/1756-3305-2-S2-S4

Faecal Cyathostomin Egg Count distribution and efficacy of anthelmintics against cyathostomins in Italy: a matter of geography?

Abstract: In the framework of a trial carried out in 2008 in Europe to evaluate the efficacy of major parasiticides against horse cyathostomins, pre- and/or post-treatment Faecal Egg Counts (FEC) were evaluated in a total of 84 yards and 2105 horses from nine different regions from the South, the Center, the North-Center and North-East of Italy. Specifically, on the basis of FECs of the horses present in each property, 60 out of the 84 yards were enrolled for a Faecal Egg Count Reduction Test (FECRT) using fenbendazole, pyrantel, ivermectin and moxidectin. Results: Of the 1646 horses bred in the 60 recruited yards, 416 animals had a FEC between 50 and 150 Eggs Per Gram (EPG) of faeces and 694 a FEC >150 EPG (i.e. with total of 1110 positive animals). Of the 1110 positive animals, those with the highest FECs (i.e. 988) were included in the FECRT. The FECRT for four anthelmintic compounds showed remarkable differences in terms of prevalence of reduced and equivocal efficacy against cyathostomins in the different areas of Italy. Administration of fenbendazole and pyrantel resulted in resistance present or suspected in about half of the yards examined while resistance to ivermectin was found in one yard from central Italy and suspected resistance was detected in three more yards, one in each the North, the Center and the South. Treatment with moxidectin was 100% effective in all yards examined. Conclusions: Cyathostomin populations in the South and the Center of Italy were more susceptible to fenbendazole and pyrantel than the populations present in the Center-North and North-Eastern areas of Italy. Fenbendazole and/or pyrantel were ineffective in almost all properties from the North of Italy. The reasons for such a difference among the Italian regions in terms of FECs and efficacy of antiparasitic drugs are discussed, together with the role that veterinarians, and horse owners and managers should have for effective worm control programs in this country.
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Publication Date: 2009-09-25 PubMed ID: 19778465PubMed Central: PMC2751840DOI: 10.1186/1756-3305-2-S2-S4Google Scholar: Lookup
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Summary

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This research paper outlines a study on the distribution of Cyathostomin Egg Counts (FEC) in horse feces in different regions of Italy and examines the effectiveness of various anthelmintic drugs in combating cyathostomins in horses. It reveals geographical differences in susceptibility and effectiveness of these drugs.

Study Design and Execution

  • The research was part of a larger trial conducted in 2008 across Europe, aimed at evaluating the efficacy of major parasiticides against horse cyathostomins.
  • A total of 84 yards and 2105 horses spanning nine diverse regions in the south, center, north-center, and north-east of Italy were evaluated for pre- and/or post-treatment Faecal Egg Counts.
  • Of these facilities, 60 were chosen for a Faecal Egg Count Reduction Test (FECRT) using four anthelmintics: fenbendazole, pyrantel, ivermectin, and moxidectin.

Results

  • From the 1646 horses bred in the 60 selected yards, 1110 animals had a FEC above 50 Eggs Per Gram (EPG) of feces.
  • Among the positive animals, those with the highest FECs, numbering 988, were included in the FECRT.
  • The results showed notable regional differences in the effectiveness of the tested drugs against cyathostomins.
  • The administration of fenbendazole and pyrantel resulted in resistance or suspected resistance in about half of the tested yards. Ivermectin resistance was found in one yard from central Italy, with suspected resistance in three more—representing the North, Center, and South. Moxidectin, however, proved 100% effective in all tested yards.

Conclusions and Further Discussion

  • The research concludes that Cyathostomin populations in the South and the Center of Italy were more susceptible to fenbendazole and pyrantel than those in the Center-North and North-Eastern areas.
  • Fenbendazole and/or pyrantel proved ineffective in nearly all properties in the North of Italy.
  • The authors discuss possible reasons for regional differences in FECs and the efficacy of anti-parasitic drugs. The potential role of veterinarians, as well as horse owners and managers in implementing effective worm control programs, is also examined.

Cite This Article

APA
Milillo P, Boeckh A, Cobb R, Otranto D, Lia RP, Perrucci S, di Regalbono AF, Beraldo P, von Samson-Himmelstjerna G, Demeler J, Bartolini R, Traversa D. (2009). Faecal Cyathostomin Egg Count distribution and efficacy of anthelmintics against cyathostomins in Italy: a matter of geography? Parasit Vectors, 2 Suppl 2(Suppl 2), S4. https://doi.org/10.1186/1756-3305-2-S2-S4

Publication

Parasites & vectors
ISSN: 1756-3305
NlmUniqueID: 101462774
Country: England
Language: English
Volume: 2 Suppl 2
Issue: Suppl 2
Pages: S4

Researcher Affiliations

Milillo, Piermarino
  • Faculty of Veterinary Medicine, University of Teramo, Italy. piermarino.milllo@gmail.com.
Boeckh, Albert
    Cobb, Rami
      Otranto, Domenico
        Lia, Riccardo P
          Perrucci, Stefania
            di Regalbono, Antonio Frangipane
              Beraldo, Paola
                von Samson-Himmelstjerna, Georg
                  Demeler, Janina
                    Bartolini, Roberto
                      Traversa, Donato

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                        Citations

                        This article has been cited 11 times.
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