Genetic Control of Albumin Phenotypes in Horses.
Abstract: By means of a starch-gel technique suggested by Kristjansson, 3 albumin phenotypes A, AB and B are demonstrable in the serum of horses. As indicated by data on the inheritance of these phenotypes and by a gene-frequency analysis of the distribution of the phenotypes in 2 breeds of horses, the results are consistent with the interpretation that the 3 phenotypes are controlled by a pair of codominant, autosomal alleles. These 3 phenotypes can be diagnosed by examining either the albumin region or the post-albumin region of the gels. Hence, diagnosis in one region serves as an independent check on the other.
Publication Date: 1963-12-01 PubMed ID: 14120321DOI: 10.3181/00379727-114-28766Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research paper explores the genetic control of three different albumin phenotypes found in horse serum. The results indicate that these three phenotypes are attributed to a pair of codominant, autosomal alleles.
Methodology and Phenotype Identification
- Scientists utilized a starch-gel technique suggested by Kristjansson to identify three different albumin phenotypes, labelled as A, AB and B, in the serum of horses.
- The albumin region or the post-albumin region of the gels were examined to diagnose these 3 phenotypes. The diagnosis in one region genetically validates the other, ensuring accuracy of the results.
Data Collection and Analysis
- Data was collected on the inheritance of these phenotypes in horses.
- A gene-frequency analysis was also performed on the distribution of the phenotypes in two different breeds of horses.
- The data and gene-frequency distribution were then interpreted and analyzed.
Results and Conclusions
- The results of the study suggest that the three albumin phenotypes are controlled by a pair of codominant, autosomal alleles. Codominant alleles are pairs of genes where both genes contribute to the phenotype, while autosomal refers to them being located on a non-sex chromosome.
- The consistency of the results in the two different breeds studied provide further support for the interpretation.
Cite This Article
APA
STORMONT C, SUZUKI Y.
(1963).
Genetic Control of Albumin Phenotypes in Horses.
Proc Soc Exp Biol Med, 114, 673-675.
https://doi.org/10.3181/00379727-114-28766 Publication
Researcher Affiliations
MeSH Terms
- Albumins
- Animals
- Blood Protein Electrophoresis
- Gene Expression Regulation
- Genetics
- Horses
- Phenotype
- Research
- Serum Albumin
Citations
This article has been cited 7 times.- HALEY LE. SERUM ALBUMIN POLYMORPHISM IN QUAIL AND CHICKEN-QUAIL HYBRIDS. Genetics 1965 Jun;51(6):983-6.
- Brown MA, Carne A, Daugherty CH, Chambers GK. Identification of a 130-kDa albumin in tuatara (Sphenodon) and detection of a novel albumin polymorphism. Biochem Genet 1995 Jun;33(5-6):189-204.
- Ashton GC, Gilmour DG, Kiddy CA, Kristjansson FK. Proposals on nomenclature of protein polymorphisms in farm livestock. Genetics 1967 Jul;56(3):353-62.
- Adams MS. Genetic diversity in serum albumin. J Med Genet 1966 Sep;3(3):198-202.
- Khanna ND, Braend M. Haemoglobin and albumin polymorphisms in Indian water buffaloes. Acta Vet Scand 1968;9(4):316-27.
- Stevens RW. Developments in veterinary science. Artificial insemination in horses: genetic potential and control. Can Vet J 1969 Aug;10(8):203-7.
- Fateh-Moghadam A, Eisenburg J, Lamerz R. [Alloalbuminemia (double albuminemia)]. Klin Wochenschr 1969 Sep 15;47(18):976-84.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists