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Journal of bacteriology2011; 193(7); 1785; doi: 10.1128/JB.01547-10

Genome sequence of Taylorella equigenitalis MCE9, the causative agent of contagious equine metritis.

Abstract: Taylorella equigenitalis is the causative agent of contagious equine metritis (CEM), a sexually transmitted infection of horses. We herein report the genome sequence of T. equigenitalis strain MCE9, isolated in 2005 from the urethral fossa of a 4-year-old stallion in France.
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Publication Date: 2011-01-28 PubMed ID: 21278298PubMed Central: PMC3067654DOI: 10.1128/JB.01547-10Google Scholar: Lookup
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  • Journal Article
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  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research uncovers the genetic sequence of Taylorella equigenitalis MCE9, the bacterium responsible for spreading contagious equine metritis, a sexually transmitted disease among horses. The strain was identified from a 4-year old stallion in France.

Introduction

  • The study focuses on determining the genome sequence of Taylorella equigenitalis MCE9, a bacterial strain responsible for contagious equine metritis (CEM).
  • Taylorella equigenitalis is the bacterium that causes CEM, a disease that is sexually transmitted among horses.

Research Context

  • The specific strain that the research focuses on, MCE9, was taken from a 4-year-old stallion that was living in France in 2005.
  • Looking into this specific strain’s genome sequence provides critical insight into the bacterium’s characteristics and behaviour.

Importance of the study

  • A detailed understanding of the genome sequence could help veterinarians and researchers develop more effective treatments for CEM.
  • It may also provide a foundation for further research into how the disease spreads and evolves over time.

Methodology

  • The genome sequence was completed using strain MCE9 of Taylorella equigenitalis.
  • The isolate was harvested from the urethral fossa of the stallion, which was later extensively studied in a research lab.

Conclusion

  • The research successfully determined the genetic sequence of T. equigenitalis MCE9.
  • This marks an important step forward in understanding and treating CEM among horses, potentially reducing its impacts on the equine community.

Cite This Article

APA
Hébert L, Moumen B, Duquesne F, Breuil MF, Laugier C, Batto JM, Renault P, Petry S. (2011). Genome sequence of Taylorella equigenitalis MCE9, the causative agent of contagious equine metritis. J Bacteriol, 193(7), 1785. https://doi.org/10.1128/JB.01547-10

Publication

Journal of bacteriology
ISSN: 1098-5530
NlmUniqueID: 2985120R
Country: United States
Language: English
Volume: 193
Issue: 7
Pages: 1785

Researcher Affiliations

Hébert, Laurent
  • Anses, Dozulé Laboratory for Equine Diseases, Unit of Bacteriology and Parasitology, 14430 Dozulé, France.
Moumen, Bouziane
    Duquesne, Fabien
      Breuil, Marie-France
        Laugier, Claire
          Batto, Jean-Michel
            Renault, Pierre
              Petry, Sandrine

                MeSH Terms

                • Animals
                • Endometritis / microbiology
                • Endometritis / veterinary
                • Female
                • Genome, Bacterial
                • Horse Diseases / microbiology
                • Horses
                • Molecular Sequence Data
                • Taylorella equigenitalis / classification
                • Taylorella equigenitalis / genetics

                References

                This article includes 11 references
                1. Aziz RK. The RAST server: Rapid annotations using subsystems technology. BMC Genomics 9:75.
                  pmc: PMC2265698pubmed: 18261238
                2. Bentley DR. Accurate whole human genome sequencing using reversible terminator chemistry. Nature 456:53-59.
                  pmc: PMC2581791pubmed: 18987734
                3. Crowhurst RC. Genital infection in mares. Vet. Rec. 100:476.
                  pubmed: 878259
                4. Duquesne F, Pronost S, Laugier C, Petry S. Identification of Taylorella equigenitalis responsible for contagious equine metritis in equine genital swabs by direct polymerase chain reaction. Res. Vet. Sci. 82:47-49.
                  pubmed: 16806331
                5. Gordon D, Abajian C, Green P. Consed: a graphical tool for sequence finishing. Genome Res. 8:195-202.
                  pubmed: 9521923
                6. Lagesen K. RNAmmer: consistent and rapid annotation of ribosomal RNA genes. Nucleic Acids Res. 35:3100-3108.
                  pmc: PMC1888812pubmed: 17452365
                7. Lowe TM, Eddy SR. tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res. 25:955-964.
                  pmc: PMC146525pubmed: 9023104
                8. Margulies M. Genome sequencing in microfabricated high-density picolitre reactors. Nature 437:376-380.
                  pmc: PMC1464427pubmed: 16056220
                9. Matsuda M, Moore JE. Recent advances in molecular epidemiology and detection of Taylorella equigenitalis associated with contagious equine metritis (CEM). Vet. Microbiol. 97:111-122.
                  pubmed: 14637043
                10. Sugimoto C, Isayama Y, Sakazaki R, Kuramochi S. Transfer of Haemophilus equigenitalis Taylor et al. 1978 to the genus Taylorella gen. nov. as Taylorella equigenitalis comb. nov.. Curr. Microbiol. 9:155-162.
                11. Timoney PJ, Ward J, Kelly P. A contagious genital infection of mares. Vet. Rec. 101:103.
                  pubmed: 906223

                Citations

                This article has been cited 13 times.
                1. Hrala M, Andrla P, Bosák J, Fedrová P, Mugutdinov A, Karpíšková R, Nedbalcová K, Raichová J, Faldyna M, Hořín P, Šmajs D. Whole genome sequences of nine Taylorella equigenitalis strains isolated in the Czech Republic between 1982-2021: Molecular dating suggests a common ancestor at the time of Roman Empire. PLoS One 2025;20(1):e0315946.
                  doi: 10.1371/journal.pone.0315946pubmed: 39752466google scholar: lookup
                2. Kinoshita Y, Kakoi H, Ishige T, Yamanaka T, Niwa H, Uchida-Fujii E, Nukada T, Ueno T. Comparison of seven nucleic acid amplification tests for detection of Taylorella equigenitalis. J Vet Med Sci 2022 Jan 24;84(1):129-132.
                  doi: 10.1292/jvms.21-0539pubmed: 34853198google scholar: lookup
                3. May CE, Guthrie AJ, Schulman ML. Direct culture-independent sequence typing of Taylorella equigenitalis obtained from genital swabs and frozen semen samples from South African horses. J Vet Diagn Invest 2019 Sep;31(5):792-794.
                  doi: 10.1177/1040638719871089pubmed: 31423914google scholar: lookup
                4. Hicks J, Stuber T, Lantz K, Erdman M, Robbe-Austerman S, Huang X. Genomic diversity of Taylorella equigenitalis introduced into the United States from 1978 to 2012. PLoS One 2018;13(3):e0194253.
                  doi: 10.1371/journal.pone.0194253pubmed: 29584782google scholar: lookup
                5. May CE, Schulman ML, Howell PG, Lourens CW, Gouws J, Joone C, Monyai MS, le Grange M, Bezuidt OK, Harper CK, Guthrie AJ. Draft Genome Sequence of Taylorella equigenitalis Strain ERC_G2224 Isolated from the Semen of a Lipizzaner Stallion in South Africa. Genome Announc 2015 Oct 15;3(5).
                  doi: 10.1128/genomeA.01205-15pubmed: 26472845google scholar: lookup
                6. Hébert L, Touzain F, de Boisséson C, Breuil MF, Duquesne F, Laugier C, Blanchard Y, Petry S. Draft Genome Sequence of Taylorella equigenitalis Strain MCE529, Isolated from a Belgian Warmblood Horse. Genome Announc 2014 Nov 26;2(6).
                  doi: 10.1128/genomeA.01214-14pubmed: 25428969google scholar: lookup
                7. Allombert J, Vianney A, Laugier C, Petry S, Hébert L. Survival of taylorellae in the environmental amoeba Acanthamoeba castellanii. BMC Microbiol 2014 Mar 19;14:69.
                  doi: 10.1186/1471-2180-14-69pubmed: 24641089google scholar: lookup
                8. Whiteson KL, Hernandez D, Lazarevic V, Gaia N, Farinelli L, François P, Pilo P, Frey J, Schrenzel J. A genomic perspective on a new bacterial genus and species from the Alcaligenaceae family, Basilea psittacipulmonis. BMC Genomics 2014 Mar 1;15:169.
                  doi: 10.1186/1471-2164-15-169pubmed: 24581117google scholar: lookup
                9. Ghosh W, Alam M, Roy C, Pyne P, George A, Chakraborty R, Majumder S, Agarwal A, Chakraborty S, Majumdar S, Gupta SK. Genome implosion elicits host-confinement in Alcaligenaceae: evidence from the comparative genomics of Tetrathiobacter kashmirensis, a pathogen in the making. PLoS One 2013;8(5):e64856.
                  doi: 10.1371/journal.pone.0064856pubmed: 23741407google scholar: lookup
                10. Motta MC, Martins AC, de Souza SS, Catta-Preta CM, Silva R, Klein CC, de Almeida LG, de Lima Cunha O, Ciapina LP, Brocchi M, Colabardini AC, de Araujo Lima B, Machado CR, de Almeida Soares CM, Probst CM, de Menezes CB, Thompson CE, Bartholomeu DC, Gradia DF, Pavoni DP, Grisard EC, Fantinatti-Garboggini F, Marchini FK, Rodrigues-Luiz GF, Wagner G, Goldman GH, Fietto JL, Elias MC, Goldman MH, Sagot MF, Pereira M, Stoco PH, de Mendonça-Neto RP, Teixeira SM, Maciel TE, de Oliveira Mendes TA, Ürményi TP, de Souza W, Schenkman S, de Vasconcelos AT. Predicting the proteins of Angomonas deanei, Strigomonas culicis and their respective endosymbionts reveals new aspects of the trypanosomatidae family. PLoS One 2013;8(4):e60209.
                  doi: 10.1371/journal.pone.0060209pubmed: 23560078google scholar: lookup
                11. Alves JM, Serrano MG, Maia da Silva F, Voegtly LJ, Matveyev AV, Teixeira MM, Camargo EP, Buck GA. Genome evolution and phylogenomic analysis of Candidatus Kinetoplastibacterium, the betaproteobacterial endosymbionts of Strigomonas and Angomonas. Genome Biol Evol 2013;5(2):338-50.
                  doi: 10.1093/gbe/evt012pubmed: 23345457google scholar: lookup
                12. Hara Y, Hayashi K, Nakajima T, Kagawa S, Tazumi A, Moore JE, Matsuda M. Molecular identification and characterization of clustered regularly interspaced short palindromic repeat (CRISPR) gene cluster in Taylorella equigenitalis. Folia Microbiol (Praha) 2013 Sep;58(5):375-84.
                  doi: 10.1007/s12223-012-0217-3pubmed: 23275249google scholar: lookup
                13. Hébert L, Moumen B, Pons N, Duquesne F, Breuil MF, Goux D, Batto JM, Laugier C, Renault P, Petry S. Genomic characterization of the Taylorella genus. PLoS One 2012;7(1):e29953.
                  doi: 10.1371/journal.pone.0029953pubmed: 22235352google scholar: lookup
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