Genome Sequences of Equine Herpesvirus 1 Strains from a European Outbreak of Neurological Disorders Linked to a Horse Gathering in Valencia, Spain, in 2021.
Abstract: Five equine herpesvirus 1 (EHV-1) genome sequences with links to an EHV-1 outbreak with neurological disorders after a horse gathering in Valencia, Spain, in February 2021, were determined. All strains showed the closest relationships to strains from Belgium and the United Kingdom, indicating a common source of infection.
Copyright © 2021 Vereecke et al.
Publication Date: 2021-05-20 PubMed ID: 34016681PubMed Central: PMC8188346DOI: 10.1128/MRA.00333-21Google Scholar: Lookup
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Summary
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This research studied the genetic sequences of the Equine Herpesvirus 1 (EHV-1) that were involved in an outbreak linked to a horse gathering in Valencia, Spain, 2021. The reported strains were found to be closely related to strains discovered in Belgium and the UK, hinting at a probable common source of infection.
Explaining the Research Study
- The study focused on the genome sequencing of EHV-1 strains. Genome sequencing refers to mapping out the entire genetic information of an organism. In the study, genome sequencing was carried out for five EHV-1 strains linked to an outbreak that occurred after a horse gathering in Valencia, Spain, in 2021.
- The EHV-1 outbreak in question was characterized by neurological disorders in horses. EHV-1, short for Equine Herpesvirus 1, is a virus that can cause a multitude of diseases in horses. One of its severe manifestations is neurological disease, characterized by symptoms like loss of coordination, weakness in limbs, and inability to stand.
- The genome sequence data derived from this study were compared with strains from other regions. The comparison revealed that the strains from Valencia showed the closest genetic relationships to those from Belgium and the United Kingdom.
Implications of the Findings
- Identifying the genetic material of the EHV-1 strains obtained from the Spanish outbreak can help epidemiologists and researchers understand the virus better, its mode of transmission, and develop strategies to prevent future outbreaks.
- The findings indicating a close relationship with strains from Belgium and the UK suggest the possibility of a common source of infection. Understanding this link can aid in the containment strategies for EHV-1 and possibly other equine diseases as well.
- This study adds invaluable information to the existing body of knowledge on the diversity and evolution of EHV-1 and can inform more effective diagnostic procedures, treatments, and prevention methods.
Cite This Article
APA
Vereecke N, Carnet F, Pronost S, Vanschandevijl K, Theuns S, Nauwynck H.
(2021).
Genome Sequences of Equine Herpesvirus 1 Strains from a European Outbreak of Neurological Disorders Linked to a Horse Gathering in Valencia, Spain, in 2021.
Microbiol Resour Announc, 10(20).
https://doi.org/10.1128/MRA.00333-21 Publication
Researcher Affiliations
- Department Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium nick.vereecke@pathosense.com.
- PathoSense BV, Lier, Belgium.
- LABÉO Frank Duncombe, Saint-Contest, France.
- Normandie University, Unicaen, Biotargen, Caen, France.
- LABÉO Frank Duncombe, Saint-Contest, France.
- Normandie University, Unicaen, Biotargen, Caen, France.
- Dierenkliniek de Bosdreef, Moerbeke-Waas, Belgium.
- PathoSense BV, Lier, Belgium.
- Department Virology, Parasitology, and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
- PathoSense BV, Lier, Belgium.
References
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