Haematological profile in foals during the first year of life.
Abstract: Foals' haematological values change constantly during their first year of life. The use of updated age-based reference intervals (RIs) is imperative for providing accurate diagnosis and optimum care for sick foals. The authors' objective was to provide updated RIs for 13 haematological values in 2, 7, 14, 30, 90, 180 and 365-day-old foals and to investigate the changes over time in each measured value. Venous blood was collected at those ages from clinically healthy foals. Thirteen haematological values were analysed. The 95% RIs were reported using a bootstrapping method. Differences over time were examined using Friedman test. RIs for each of the measured values were calculated. Results showed noticeable trends in changes over time in several values. Nevertheless, white blood cell counts significantly increased between day 2 and day 90 (P=0.011) while lymphocyte counts increased from day 2 up to day 180 (P=0.033). The mean corpuscular haemoglobin and mean corpuscular volume (P=0.011) significantly decreased between day 2 and day 90. Normal haematological values in foals not only differ from those in adult horses but also change throughout the first year of life; thus, it is critical that clinicians use age-based RIs when treating sick foals.
© British Veterinary Association 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Publication Date: 2019-04-17 PubMed ID: 30995997DOI: 10.1136/vr.104461Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research article provides updated reference intervals (RIs) for 13 haematological values in foals over their first year of life, emphasizing the need for clinicians to use age-based RIs when treating young horses.
Objective and Methodology of Research
- The aim of the researchers was to provide updated RIs for 13 haematological values in foals when they are 2, 7, 14, 30, 90, 180, and 365 days old.
- To do this, they gathered venous blood samples from healthy foals at those ages and analysed the samples based on 13 haematological values.
- The 95% RIs for each of these values were determined using a statistical method known as bootstrapping.
- A Friedman test was applied to study the fluctuations in each measured value over time.
Results of the Research
- The findings showed prominent trends in the changes over time for several of the haematological values.
- The count of white blood cells notably increased between the 2nd and 90th day.
- Lymphocyte counts increased from the 2nd day up to the 180th day.
- On the other hand, the mean corpuscular haemoglobin and mean corpuscular volume significantly dwindled between day 2 and day 90.
Significance of the Research
- The study emphasizes that the normal haematological values in foals not only differ from those in full-grown horses but also vary significantly throughout the first year of the foals’ life.
- Therefore, it is critical for clinicians to use age-based reference intervals when offering treatment to ill foals.
Cite This Article
APA
Faramarzi B, Rich L.
(2019).
Haematological profile in foals during the first year of life.
Vet Rec, 184(16), 503.
https://doi.org/10.1136/vr.104461 Publication
Researcher Affiliations
- Western University of Health Sciences, Pomona, California, USA.
- Antech Diagnostics Inc, Irvine, California, USA.
MeSH Terms
- Age Factors
- Animals
- Animals, Newborn
- California
- Hematologic Tests / statistics & numerical data
- Hematologic Tests / veterinary
- Horses / blood
- Reference Values
Conflict of Interest Statement
Competing interests: None declared.
Citations
This article has been cited 2 times.- Osman T, Probo M, Monaco D, Shafiek HK, Freccero F. Blood Gas, Acid-Base and Electrolyte Analysis in Healthy Dromedary Camel Calves up to 21 Days of Life. Animals (Basel) 2023 Mar 22;13(6).
- Palmisano M, Javsicas L, McNaughten J, Gamsjäger L, Renaud DL, Gomez DE. Effect of plasma transfusion on serum amyloid A concentration in healthy neonatal foals and foals with failure of transfer of passive immunity. J Vet Intern Med 2023 Mar;37(2):697-702.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists