Hair cortisol concentration is inversely related to the severity of equine squamous gastric disease.
Abstract: Equine squamous gastric disease (ESGD) is common in horses and many factors, including stress, may play a role in lesion development. Hair cortisol concentration (HCC) provides a measure of medium to long-term stress and therefore, the relationship between HCC and ESGD was examined in this study. Hair samples were collected from 25 horses and gastroscopy was performed to determine the presence and severity of ESGD. Hair cortisol concentrations were lower in horses with ESGD (P = 0.014), and negatively correlated with lesion severity. Mares had lower HCC than geldings (P = 0.031), and a higher prevalence of ESGD, while age had no significant effect. Further studies are required to determine the relevance of the association between HCC and ESGD.
Copyright © 2019 Elsevier Ltd. All rights reserved.
Publication Date: 2019-05-24 PubMed ID: 31239166DOI: 10.1016/j.tvjl.2019.05.009Google Scholar: Lookup
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- Journal Article
Summary
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This research investigates stress in horses in relation to equine squamous gastric disease (ESGD), finding that lower hair cortisol levels correlate with more severe ESGD symptoms.
Objectives and Methods
- The main aim of this study was to explore the relationship between hair cortisol concentration (HCC) – a marker of medium to long-term stress – and the occurrence and severity of ESGD in horses.
- The researchers collected hair samples from 25 horses and performed gastroscopies on them to identify the presence and evaluate the severity of ESGD.
Findings
- The findings revealed that horses with ESGD had noticeably lower HCC, indicating an inverse relationship between stress levels and ESGD severity.
- Interestingly, the study found that mares demonstrated lower HCC compared to geldings and also showed a higher prevalence of ESGD.
- The researchers found no significant impact of the age of the horses on these outcomes.
Conclusion
- The study successfully identified a clear association between lower HCC and increased severity of ESGD, suggesting a potential link between lower stress levels and ESGD severity.
- However, the researchers concluded the study by suggesting that more detailed research is necessary to fully understand the significance and implications of this correlation.
Implications
- This research may hold important implications for understanding how stress impacts the health and well-being of horses, specifically in relation to ESGD.
- It could potentially influence future approaches to ESGD prevention and treatment, emphasizing the importance of stress management in equine health care.
Cite This Article
APA
Prinsloo M, Hynd P, Franklin S, Weaver S, van den Boom R.
(2019).
Hair cortisol concentration is inversely related to the severity of equine squamous gastric disease.
Vet J, 249, 58-59.
https://doi.org/10.1016/j.tvjl.2019.05.009 Publication
Researcher Affiliations
- School of Animal and Veterinary Sciences, The University of Adelaide, Australia.
- Department of Animal and Veterinary Bioscience, School of Animal and Veterinary Sciences, The University of Adelaide, Australia.
- Department of Equine Health, School of Animal and Veterinary Sciences, The University of Adelaide, Australia.
- Department of Animal and Veterinary Bioscience, School of Animal and Veterinary Sciences, The University of Adelaide, Australia.
- Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. Electronic address: r.vandenboom@uu.nl.
MeSH Terms
- Animals
- Epithelial Cells
- Female
- Hair / chemistry
- Horse Diseases / metabolism
- Horses
- Hydrocortisone / metabolism
- Male
- Stomach Diseases / metabolism
- Stomach Diseases / veterinary
Citations
This article has been cited 7 times.- Kranenburg LC, van der Poel SH, Warmelink TS, van Doorn DA, van den Boom R. Changes in Management Lead to Improvement and Healing of Equine Squamous Gastric Disease.. Animals (Basel) 2023 Apr 28;13(9).
- Vokes J, Lovett A, Sykes B. Equine Gastric Ulcer Syndrome: An Update on Current Knowledge.. Animals (Basel) 2023 Apr 5;13(7).
- Saluti G, Ricci M, Castellani F, Colagrande MN, Di Bari G, Vulpiani MP, Cerasoli F, Savini G, Scortichini G, D'Alterio N. Determination of hair cortisol in horses: comparison of immunoassay vs LC-HRMS/MS.. Anal Bioanal Chem 2022 Nov;414(28):8093-8105.
- Cerasoli F, Podaliri Vulpiani M, Saluti G, Conte A, Ricci M, Savini G, D'Alterio N. Assessment of Welfare in Groups of Horses with Different Management, Environments and Activities by Measuring Cortisol in Horsehair, Using Liquid Chromatography Coupled to Hybrid Orbitrap High-Resolution Mass Spectrometry.. Animals (Basel) 2022 Jul 6;12(14).
- Lanci A, Mariella J, Ellero N, Faoro A, Peric T, Prandi A, Freccero F, Castagnetti C. Hair Cortisol and DHEA-S in Foals and Mares as a Retrospective Picture of Feto-Maternal Relationship under Physiological and Pathological Conditions.. Animals (Basel) 2022 May 14;12(10).
- Hewetson M, Tallon R. Equine Squamous Gastric Disease: Prevalence, Impact and Management.. Vet Med (Auckl) 2021;12:381-399.
- Gardela J, Carbajal A, Tallo-Parra O, Olvera-Maneu S, Álvarez-Rodríguez M, Jose-Cunilleras E, López-Béjar M. Temporary Relocation during Rest Periods: Relocation Stress and Other Factors Influence Hair Cortisol Concentrations in Horses.. Animals (Basel) 2020 Apr 8;10(4).
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