[Individual hormonal profiles of blood progesterone and estradiol-17β during the course of a reproductive cycle in mares].
Abstract: This study presents the individual course of estradiol-17ß and progesterone concentrations in blood during the reproductive cycle in mares in order to point out physiological differences between individual animals and to aid in the interpretation of hormone values. Methods: Concentrations of estradiol-17ß and progesterone were determined in seven mares over the course of their cycle. One mare was excluded from the study due to a physiologically deviating cycle. In addition, the mares' ovaries were examined via ultrasound on a daily basis in order to match the hormone values to morphological changes of the ovaries. Results: In some cases, the mares showed considerable individual differences in their hormone concentrations, which also differed from the published comparative values in the literature. For example, two mares showed progesterone levels above basal levels at the time of ovulation. The postovulatory progesterone concentrations of the mares are characterized by marked fluctuations, which makes it difficult to provide reference values in the different sections of the corpus luteum phase. The length of the plateau phases averaged 12.3±1.5 days. The mare with double ovulation showed the highest progesterone concentrations. Conclusions: The measurement of plasma progesterone levels in mares should be interpreted only in the context of other test results. The very wide variation in estradiol-17ß concentrations makes it questionable whether the determination of this hormone value is of diagnostic value. Conclusions: When interpreting steroid hormone values in the ingravid cycle of a mare, the individual concentration courses must be taken into consideration, as they may deviate significantly from the published reference values. Unassigned: Die Studie stellt den individuellen Verlauf der Konzentrationen von Östradiol-17ß und Progesteron im Blut von Stuten über einen Zyklus dar, um auf physiologische individuelle Unterschiede zwischen einzelnen Tieren hinzuweisen und Interpretationshilfen von Hormonwerten zu geben. Methods: An 7 Stuten wurde über den Zyklusverlauf die Konzentrationen an Progesteron und Östradiol-17ß bestimmt. Eine Stute wurde aufgrund eines vom physiologischen Zyklus abweichenden Verlaufs aus der Beurteilung ausgeschlossen. Zusätzlich wurden die Ovarien täglich sonografisch untersucht, um die Hormonwerte morphologischen Veränderungen auf den Ovarien zuordnen zu können. Unassigned: Teilweise zeigen Stuten erhebliche individuelle Unterschiede in ihren Hormonverläufen, die sich auch von den veröffentlichten Vergleichswerten in der Literatur unterscheiden. So zeigten 2 Stuten zum Zeitpunkt der Ovulation einen Progesteronwert oberhalb des Basalniveaus. Die postovulatorischen Progesteronverläufe der Stuten zeigen deutliche Schwankungen, was die Angabe von Referenzwerten in den verschiedenen Abschnitten der Gelbkörperphase erschwert. Die Länge der Plateauphasen beträgt im Durchschnitt 12,3±1,5 Tage. Die Stute mit der Doppelovulation zeigte die höchsten Progesteronkonzentrationen. Unassigned: Die Messung von Plasmaprogesteronwerten bei Stuten sollten nur im Zusammenhang mit weiteren Untersuchungsergebnissen interpretiert werden. Die sehr starken Schwankungen der Östradiol-17ß-Konzentrationen machen es fraglich, ob die Bestimmung dieses Hormonwertes einen diagnostischen Nutzen hat. Unassigned: Bei der Interpretation von Steroidhormonwerten im ingraviden Zyklus einer Stute sind die individuellen Verläufe zu beachten, die teilweise deutlich von den veröffentlichten Referenzwerten abweichen.
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Publication Date: 2024-05-03 PubMed ID: 38701799DOI: 10.1055/a-2276-5226Google Scholar: Lookup
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- English Abstract
- Journal Article
Summary
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The research investigates the individual differences in the progression of estradiol-17ß and progesterone concentrations in mares over a reproductive cycle, highlighting the significance of considering individual hormonal courses when interpreting hormone levels.
Methods
- The researchers studied the hormonal changes in seven different mares throughout their reproductive cycle.
- The concentration of estradiol-17ß and progesterone in the blood of these mares was determined.
- One mare was excluded from the study due to abnormalities in her physiological cycle.
- Additionally, daily ultrasound examinations of the mares’ ovaries were conducted to understand the relation between morphological changes in the ovaries with the hormone levels.
Results
- Notable individual variations were observed in the hormonal courses of the tested mares, which also varied from the standard values available in literature.
- At the time of ovulation, two mares showed progesterone levels above their basal levels.
- Post-ovulation progesterone levels exhibited considerable variations, making it challenging to establish reference values for different sections of the corpus luteum phase.
- The length of the plateau phases averaged around 12.3 ± 1.5 days. The mare that had double ovulation displayed the highest progesterone concentrations.
Conclusions
- Measurement of plasma progesterone levels in mares should be interpreted in conjunction with other test results.
- The marked variation in estradiol-17ß concentrations raises questions about the diagnostic value of this hormonal measurement.
- When interpreting steroid hormone values in the reproductive cycle of a mare, it’s important to consider the individual concentration patterns, as they may significantly deviate from published reference values.
Cite This Article
APA
Laufkötter S, Längerer L, Wehrend A.
(2024).
[Individual hormonal profiles of blood progesterone and estradiol-17β during the course of a reproductive cycle in mares].
Tierarztl Prax Ausg G Grosstiere Nutztiere, 52(2), 88-95.
https://doi.org/10.1055/a-2276-5226 Publication
Researcher Affiliations
- Tierklinik für Reproduktionsmedizin und Neugeborenenkunde, Justus-Liebig-Universität, Gießen.
- Tierklinik für Reproduktionsmedizin und Neugeborenenkunde, Justus-Liebig-Universität, Gießen.
- Tierklinik für Reproduktionsmedizin und Neugeborenenkunde, Justus-Liebig-Universität, Gießen.
MeSH Terms
- Animals
- Horses / blood
- Horses / physiology
- Female
- Progesterone / blood
- Estradiol / blood
- Estrous Cycle / physiology
- Estrous Cycle / blood
- Ovary / physiology
- Ovary / diagnostic imaging
- Ovary / anatomy & histology
- Ovulation / physiology
- Ovulation / blood
Conflict of Interest Statement
Die Autoren bestätigen, dass kein Interessenkonflikt besteht.
Citations
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