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Locoweed (Astragalus lentiginosus) poisoning in cattle and horses.

Abstract: Of 70 Aberdeen-Angus cows which ate locoweed (Astragalus lentiginosus) during rotational grazing in Utah, because it was the only green feed available at the time, a large number aborted. All the cattle showed signs of poisoning, but recovered when removed from the pasture. There were signs of poisoning also in 12 horses, and though they seemed to recover signs of permanent damage to the central nervous system remained. Hereford cattle grazing plots with a similar proportion of locoweed were not affected, but for them other green herbage was available
Publication Date: 1969-08-01 PubMed ID: 5816061
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  • Journal Article

Summary

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This research article explores the negative effects of locoweed (Astragalus lentiginosus) ingestion on Aberdeen-Angus cows and horses in Utah, leading to disruptive health issues such as abortions in cows and long-lasting damage to horses’ central nervous system.

Study Context and Methodology

  • This study was conducted amidst Aberdeen-Angus cows and horses that consumed locoweed during a rotational grazing regime in Utah.
  • The locoweed became the only green feed available for these animals at the time, leading to their inevitable consumption of the toxic plant.
  • Observational data on the symptoms and severity of locoweed poisoning in both Aberdeen-Angus cows and horses were collected. In addition, Hereford cattle, which had other green forage available and thus did not consume significant amounts of locoweed, were observed for comparative purposes.

Findings in Aberdeen-Angus Cows

  • Of the 70 Aberdeen-Angus cows that consumed locoweed, a vast majority reportedly aborted.
  • While all the cattle demonstrated signs of locoweed poisoning, they all recovered once they were removed from the field containing locoweed.

Findings in Horses

  • Besides the cows, 12 horses that consumed locoweed showed symptoms of poisoning.
  • Even though these horses appeared to recover, signs of lasting damage to the central nervous system remained.

Comparative Observations with Hereford Cattle

  • Hereford cattle, which were exposed to a similar quantity of locoweed, did not display any signs of poisoning.
  • This is attributed to the fact that the Hereford cattle had other green vegetation available to feed upon, suppressing their need to consume the toxic locoweed.

Implications of the Research

  • The study provides clear evidence of the detrimental impact of locoweed on cattle and horses, particularly if it is the only source of green feed available.
  • The results underline the importance of providing a varied and non-toxic food source for grazing animals to prevent such health issues.
  • The contrast in the health outcomes between the Aberdeen-Angus cows, horses, and the Hereford cattle underscores the role of dietary diversity in preventing toxic plant ingestion and its aftermath.

To sum up, the research highlights the severe health consequences of locoweed consumption in grazing livestock and underscores the importance of maintaining dietary variety to prevent such outcomes.

Cite This Article

APA
James LF, Van Kampen KR, Staker GR. (1969). Locoweed (Astragalus lentiginosus) poisoning in cattle and horses. J Am Vet Med Assoc, 155(3), 525-530.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 155
Issue: 3
Pages: 525-530

Researcher Affiliations

James, L F
    Van Kampen, K R
      Staker, G R

        MeSH Terms

        • Animals
        • Cattle
        • Cattle Diseases / etiology
        • Horse Diseases / etiology
        • Horses
        • Plant Poisoning / veterinary

        Citations

        This article has been cited 8 times.
        1. Creamer R, Hille DB, Neyaz M, Nusayr T, Schardl CL, Cook D. Genetic Relationships in the Toxin-Producing Fungal Endophyte, Alternaria oxytropis Using Polyketide Synthase and Non-Ribosomal Peptide Synthase Genes. J Fungi (Basel) 2021 Jul 6;7(7).
          doi: 10.3390/jof7070538pubmed: 34356917google scholar: lookup
        2. Takeda S, Tanaka H, Shimada A, Morita T, Ishihara A, Adilbish A, Delgermaa B, Gungaa O. Cerebellar ataxia suspected to be caused by Oxytropis glabra poisoning in western Mongolian goats. J Vet Med Sci 2014 Jun;76(6):839-46.
          doi: 10.1292/jvms.14-0023pubmed: 24572629google scholar: lookup
        3. Hartley WJ. Some observations on the pathology of Swainsona SPP poisoning in farm livestock in Eastern Australia. Acta Neuropathol 1971;18(4):342-55.
          doi: 10.1007/BF00688447pubmed: 5106485google scholar: lookup
        4. Harries WN, Baker FP, Johnston A. Case report. An outbreak of locoweed poisoning in horses in Southwestern Alberta. Can Vet J 1972 Jun;13(6):141-5.
          pubmed: 5036903
        5. Hartley WJ, Blakemore WF. Neurovisceral storage and dysmyelinogenesis in neonatal goats. Acta Neuropathol 1973;25(4):325-33.
          doi: 10.1007/BF00691760pubmed: 4796034google scholar: lookup
        6. James LF, Foote W. Estrogenic properties of locoweed (Astragalus lentiginosus). Can J Comp Med 1972 Oct;36(4):360-5.
          pubmed: 4263915
        7. James LF. Effect of locoweed (Astragalus ientiginosus) feeding of fetal lamb development. Can J Comp Med 1976 Oct;40(4):380-4.
          pubmed: 1033781
        8. Stegelmeier BL, David TZ, Panter KE, Welch KD, Knoppel EL. A Review of Intermittent Poisoning to Mitigate Toxic Plant-Induced Disease in Livestock. Vet Sci 2024 Dec 31;12(1).
          doi: 10.3390/vetsci12010013pubmed: 39852888google scholar: lookup