MicroPulse™ transscleral cyclophotocoagulation in the equine patient: A case series of four horses.
Abstract: To describe the clinical application and outcome of MicroPulse™ transscleral cyclophotocoagulation (MP-TSCPC) treatment in horses with glaucoma. Methods: Four client-owned horses with primary (n = 2) or secondary (n = 2) glaucoma. Methods: Horses were treated with MP-TSCPC under standing sedation with a minimum of 30 days of follow-up (range 30-1241 days). Affected eyes were treated with a 31.3% duty cycle and 3000 mW laser power for a total of 180 s. Data collected included signalment, pre- and post-procedure intraocular pressures (IOPs), laser settings, medications, complications, and repeat therapy. Results: Four horses (5 eyes) received at least one treatment with MP-TSCPC. Mean preoperative IOP was 44 mmHg (range 33-49 mmHg). The immediate mean postoperative IOP was 34 mmHg (4 eyes; range 19-55 mmHg). At 1 week, IOP was 38 mmHg (5 eyes; range 21-80 mmHg), at 2 weeks was 40 mmHg (3 eyes, range 17-80 mmHg), at 1 month was 35 mmHg (5 eyes; range 20-50 mmHg), at 3 months was 18 mmHg (2 eyes; range 14-21 mmHg), at 6 months was 35 mmHg (2 eyes; range 30-39 mmHg), and at >300 days was 24 mmHg (3 eyes; range 18-29 mmHg). Complications included corneal ulceration (n = 1 eye), uncontrolled IOP (n = 3 eyes), and need for repeat treatment (n = 2 eyes). Conclusions: MP-TSCPC used with the above-described settings was unsuccessful in treating the majority of cases. Future studies should be targeted at primary glaucoma cases and with use of alternative laser settings.
© 2024 American College of Veterinary Ophthalmologists.
Publication Date: 2024-01-15 PubMed ID: 38225805DOI: 10.1111/vop.13184Google Scholar: Lookup
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Summary
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The research discusses the application of MicroPulse™ transscleral cyclophotocoagulation (MP-TSCPC) technique for the treatment of glaucoma in horses and its outcomes.
Research Methodology
- The objective of the study was to evaluate the efficiency of the MP-TSCPC treatment method in glaucoma in horses.
- The research was carried out on four client-owned horses, which were diagnosed with primary (n = 2) or secondary (n = 2) glaucoma.
- The horses were treated with this method under standing sedation and the post-treatment recovery and conditions were followed up for a minimum of 30 to up to 1241 days.
- The treatment process involves using a 31.3% duty cycle and 3000 mW laser power for a span of 180 seconds.
- Data like signalment, pre and post-procedure intraocular pressures (IOPs), laser settings used, medications prescribed, any complications faced, and need for repeat treatment were collected and thoroughly studied.
Results of the Treatment
- A total of four horses (five eyes) received the MP-TSCPC treatment at least once.
- The preoperative average IOP was 44 mmHg, which reduced to an immediate postoperative average of 34 mmHg, indicating initial successful reduction of the IOP over the short term.
- The IOP created a fluctuating trend over different timeframes but overall, it showed variability, not necessarily maintaining the early significant drop that was recorded immediately postoperative.
- The greatest reduction was seen at >300 days, where IOP dropped to an average of 24 mmHg.
- However, there were complications associated with this treatment process. These complications included corneal ulceration in one eye, uncontrolled IOP in three eyes, and the need for repeat treatment in two eyes.
Conclusions derived from the Research
- The use of MP-TSCPC for the treatment of glaucoma in horses, with the settings described in the study, did not prove successful in the majority of the studied cases.
- Considering the temporary early successes and later reduction in IOP at >300 days, the authors suggest that future studies should be aimed at cases with primary glaucoma and potentially explore alternative laser settings for greater efficacy.
Cite This Article
APA
Sturbaum AM, Kaiser KJ, Riesberg JS.
(2024).
MicroPulse™ transscleral cyclophotocoagulation in the equine patient: A case series of four horses.
Vet Ophthalmol, 28(2), 465-473.
https://doi.org/10.1111/vop.13184 Publication
Researcher Affiliations
- Animal Eye Clinic of Spokane, Washington State University, Veterinary Specialty Teaching Clinic, Spokane, Washington, USA.
- Animal Eye Clinic of Spokane, Washington State University, Veterinary Specialty Teaching Clinic, Spokane, Washington, USA.
- MedVet Salt Lake City, Emergency Vet & Specialty Care, Salt Lake City, Utah, USA.
MeSH Terms
- Animals
- Horses
- Horse Diseases / surgery
- Male
- Female
- Glaucoma / veterinary
- Glaucoma / surgery
- Laser Coagulation / veterinary
- Laser Coagulation / methods
- Ciliary Body / surgery
- Treatment Outcome
- Intraocular Pressure
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