Performance comparison between 8- and 14-bit-depth imaging in polarization-sensitive swept-source optical coherence tomography.
Abstract: Recently the effects of reduced bit-depth acquisition on swept-source optical coherence tomography (SS-OCT) image quality have been evaluated by using simulations and empirical studies, showing that image acquisition at 8-bit depth allows high system sensitivity with only a minimal drop in the signal-to-noise ratio compared to higher bit-depth systems. However, in these studies the 8-bit data is actually 12- or 14-bit ADC data numerically truncated to 8 bits. In practice, a native 8-bit ADC could actually possess a true bit resolution lower than this due to the electronic jitter in the converter etc. We compare true 8- and 14-bit-depth imaging of SS-OCT and polarization-sensitive SS-OCT (PS-SS-OCT) by using two hardware-synchronized high-speed data acquisition (DAQ) boards. The two DAQ boards read exactly the same imaging data for comparison. The measured system sensitivity at 8-bit depth is comparable to that for 14-bit acquisition when using the more sensitive of the available full analog input voltage ranges of the ADC. Ex-vivo structural and birefringence images of equine tendon indicate no significant differences between images acquired by the two DAQ boards suggesting that 8-bit DAQ boards can be employed to increase imaging speeds and reduce storage in clinical SS-OCT/PS-SS-OCT systems. One possible disadvantage is a reduced imaging dynamic range which can manifest itself as an increase in image artifacts due to strong Fresnel reflection.
Publication Date: 2011-03-04 PubMed ID: 21483604PubMed Central: PMC3072122DOI: 10.1364/BOE.2.000794Google Scholar: Lookup
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- Journal Article
Summary
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The research work compares the performance of 8-bit and 14-bit image acquisition in Swept-Source Optical Coherence Tomography (SS-OCT) and Polarization-Sensitive SS-OCT (PS-SS-OCT). The findings suggest that using an 8-bit data acquisition board can maintain high system sensitivity, increase imaging speeds, and reduce storage while only marginally decreasing imaging dynamic range.
Study Overview
- The research examines the implications of reduced bit-depth acquisition on the image quality of SS-OCT and PS-SS-OCT systems. The comparison is done between 8-bit and 14-bit imaging.
- Previous studies considered 8-bit data derived from numerically truncated 12- or 14-bit ADC data. However, this study uses true 8-bit ADC for the comparison to account for electronic jitter in the converter that can potentially reduce bit resolution.
Methodology
- The researchers used two hardware-synchronized high-speed data acquisition (DAQ) boards for the comparison. Both the DAQ boards read exactly the same imaging data, ensuring a fair comparison.
- Ex-vivo structural and birefringence images of equine tendon were used for comparison. This helped validate the findings in a “real world” application, showcasing the potential implications on clinical SS-OCT/PS-SS-OCT systems.
Findings
- The researchers observed that the system sensitivity at 8-bit depth is comparable to that for 14-bit acquisition when using the more sensitive of the full analog input voltage ranges.
- There were no significant differences between images acquired by the two DAQ boards, suggesting 8-bit DAQ boards can be employed to increase imaging speeds and reduce storage.
- One possible disadvantage of an 8-bit board was observed: a reduced imaging dynamic range. This could potentially lead to an increase in image artifacts due to strong Fresnel reflection. However, the magnitude of this disadvantage was not quantified in the study.
Implications
- The study brings important implications for clinical SS-OCT and PS-SS-OCT systems, suggesting they can effectively utilize 8-bit DAQ boards to boost speeds and decrease storage needs.
- As these systems are widely used in ophthalmic imaging and related applications, the results can hasten the integration and adoption of 8-bit ADCs in their design and operation, provided the trade-off due to reduced imaging dynamic range is deemed acceptable for the specific application at hand.
Cite This Article
APA
Lu Z, Kasaragod DK, Matcher SJ.
(2011).
Performance comparison between 8- and 14-bit-depth imaging in polarization-sensitive swept-source optical coherence tomography.
Biomed Opt Express, 2(4), 794-804.
https://doi.org/10.1364/BOE.2.000794 Publication
Researcher Affiliations
- Department of Materials Science and Engineering, the Kroto Research Institute, University of Sheffield, North Campus, Broad Lane, Sheffield, S3 7HQ, UK.
References
This article includes 26 references
- Tomlins PH, Wang RK. Theory, developments and applications of optical coherence tomography. J. Phys. D Appl. Phys. 38(15), 2519–2535 (2005).
- Oh WY, Yun SH, Tearney GJ, Bouma BE. 115 kHz tuning repetition rate ultrahigh-speed wavelength-swept semiconductor laser.. Opt Lett 2005 Dec 1;30(23):3159-61.
- Huber R, Wojtkowski M, Fujimoto JG. Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography.. Opt Express 2006 Apr 17;14(8):3225-37.
- Huber R, Adler DC, Fujimoto JG. Buffered Fourier domain mode locking: Unidirectional swept laser sources for optical coherence tomography imaging at 370,000 lines/s.. Opt Lett 2006 Oct 15;31(20):2975-7.
- Huber R, Adler DC, Srinivasan VJ, Fujimoto JG. Fourier domain mode locking at 1050 nm for ultra-high-speed optical coherence tomography of the human retina at 236,000 axial scans per second.. Opt Lett 2007 Jul 15;32(14):2049-51.
- Potsaid B, Gorczynska I, Srinivasan VJ, Chen Y, Jiang J, Cable A, Fujimoto JG. Ultrahigh speed spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second.. Opt Express 2008 Sep 15;16(19):15149-69.
- Yun SH, Boudoux C, Tearney GJ, Bouma BE. High-speed wavelength-swept semiconductor laser with a polygon-scanner-based wavelength filter.. Opt Lett 2003 Oct 15;28(20):1981-3.
- Yamanari M, Makita S, Lim Y, Yasuno Y. Full-range polarization-sensitive swept-source optical coherence tomography by simultaneous transversal and spectral modulation.. Opt Express 2010 Jun 21;18(13):13964-80.
- Oh WY, Vakoc BJ, Shishkov M, Tearney GJ, Bouma BE. >400 kHz repetition rate wavelength-swept laser and application to high-speed optical frequency domain imaging.. Opt Lett 2010 Sep 1;35(17):2919-21.
- Goldberg BD, Vakoc BJ, Oh WY, Suter MJ, Waxman S, Freilich MI, Bouma BE, Tearney GJ. Performance of reduced bit-depth acquisition for optical frequency domain imaging.. Opt Express 2009 Sep 14;17(19):16957-68.
- Yasuno Y, Makita S, Endo T, Aoki G, Sumimura H, Itoh M, Yatagai T. One-shot-phase-shifting Fourier domain optical coherence tomography by reference wavefront tilting.. Opt Express 2004 Dec 13;12(25):6184-91.
- Wieser W, Biedermann BR, Klein T, Eigenwillig CM, Huber R. Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second.. Opt Express 2010 Jul 5;18(14):14685-704.
- Yamanari M, Makita S, Yasuno Y. Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation.. Opt Express 2008 Apr 14;16(8):5892-906.
- Yamanari M, Lim Y, Makita S, Yasuno Y. Visualization of phase retardation of deep posterior eye by polarization-sensitive swept-source optical coherence tomography with 1-microm probe.. Opt Express 2009 Jul 20;17(15):12385-96.
- Yamanari M, Makita S, Madjarova VD, Yatagai T, Yasuno Y. Fiber-based polarization-sensitive Fourier domain optical coherence tomography using B-scan-oriented polarization modulation method.. Opt Express 2006 Jul 10;14(14):6502-15.
- Jiao S, Todorović M, Stoica G, Wang LV. Fiber-based polarization-sensitive Mueller matrix optical coherence tomography with continuous source polarization modulation.. Appl Opt 2005 Sep 10;44(26):5463-7.
- Park BH, Pierce MC, Cense B, de Boer JF. Jones matrix analysis for a polarization-sensitive optical coherence tomography system using fiber-optic components.. Opt Lett 2004 Nov 1;29(21):2512-4.
- Park BH, Pierce MC, Cense B, de Boer JF. Optic axis determination accuracy for fiber-based polarization-sensitive optical coherence tomography.. Opt Lett 2005 Oct 1;30(19):2587-9.
- Yun S, Tearney G, de Boer J, Iftimia N, Bouma B. High-speed optical frequency-domain imaging.. Opt Express 2003 Nov 3;11(22):2953-63.
- Chen Y, de Bruin DM, Kerbage C, de Boer JF. Spectrally balanced detection for optical frequency domain imaging.. Opt Express 2007 Dec 10;15(25):16390-9.
- Hee MR, Huang D, Swanson EA, Fujimoto JG. Polarization-sensitive low-coherence reflectometer for birefringence characterization and ranging. J. Opt. Soc. Am. B 9(6), 903–908 (1992).
- Hitzenberger C, Goetzinger E, Sticker M, Pircher M, Fercher A. Measurement and imaging of birefringence and optic axis orientation by phase resolved polarization sensitive optical coherence tomography.. Opt Express 2001 Dec 17;9(13):780-90.
- de Boer JF, Milner TE, van Gemert MJ, Nelson JS. Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography.. Opt Lett 1997 Jun 15;22(12):934-6.
- de Boer JF, Milner TE, Nelson JS. Determination of the depth-resolved Stokes parameters of light backscattered from turbid media by use of polarization-sensitive optical coherence tomography.. Opt Lett 1999 Mar 1;24(5):300-2.
- Saxer CE, de Boer JF, Park BH, Zhao Y, Chen Z, Nelson JS. High-speed fiber based polarization-sensitive optical coherence tomography of in vivo human skin.. Opt Lett 2000 Sep 15;25(18):1355-7.
- Yao G, Wang LV. Two-dimensional depth-resolved Mueller matrix characterization of biological tissue by optical coherence tomography.. Opt Lett 1999 Apr 15;24(8):537-9.
Citations
This article has been cited 2 times.- Hao Q, Zhou K, Yang J, Hu Y, Chai Z, Ma Y, Liu G, Zhao Y, Gao S, Liu J. High signal-to-noise ratio reconstruction of low bit-depth optical coherence tomography using deep learning.. J Biomed Opt 2020 Nov;25(12).
- Dsouza R, Won J, Monroy GL, Spillman DR, Boppart SA. Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications.. J Biomed Opt 2018 Sep;23(9):1-11.
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