Analyze Diet
Journal of equine veterinary science2018; 72; 79-83; doi: 10.1016/j.jevs.2018.10.025

Preliminary Observations of the Effect of Garlic on Egg Shedding in Horses Naturally Infected by Intestinal Strongyles.

Abstract: Intestinal strongyles are the most common endoparasites of horses, and anthelmintic treatments are the main strategy to control these nematodes. However, the development of anthelmintic resistance has led to a decreased efficacy of synthetic drugs, and for this reason, there is a growing interest in alternative control strategies as the use of medicinal plants. The aim of the present study was to determine the in vivo efficacy of garlic (Allium sativum) in horses naturally infected by intestinal strongyles. The field trial was conducted in a horse trotter farm in Southern Italy. Fifteen mares were selected based on fecal egg count >200 eggs per gram and allocated into three groups of five animals: fresh garlic group (FG group), animals received 40 g of fresh crushed garlic once daily for 15 days; dry garlic group (DG group), animals received 40 g of commercial dry garlic flakes food supplement once daily for 15 days; and control group (C group), not treated. Two weeks after the first administration of garlic, fecal egg count reduction test showed failure of garlic to reduce intestinal strongyles egg shedding (-11.7% and -19.4% for FG and DG groups, respectively). Red blood cell count values were in the normal ranges over the entire period of garlic administration. In our study model, the oral administration of garlic formulations has no effect on reducing the egg shedding of intestinal strongyles, and the garlic supplementation over a short period of time is not responsible for hematological changes in horses.
Publication Date: 2018-11-03 PubMed ID: 30929787DOI: 10.1016/j.jevs.2018.10.025Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study aimed to investigate whether garlic could reduce the shedding of eggs in horses naturally infected with intestinal strongyles. The results indicate that the application of both fresh and dried garlic had no significant effect on egg shedding, and did not lead to any hematological changes in horses.

Research Objective

  • The purpose of this research was to find out whether the administration of garlic (Allium sativum), a commonly used medicinal plant, could effectively reduce the shedding of eggs in horses infected with intestinal strongyles. The researchers pursued this line of inquiry due to the increasing resistance of these endoparasites to synthetic drugs.

Methodology

  • The research took place on a trotter horse farm in Southern Italy. Fifteen female horses that showed a high fecal egg count (over 200 eggs per gram) were selected for the study. These horses were divided into three groups: the first group was given 40 grams of fresh crushed garlic daily for 15 days, the second group was given a daily supplementary food of 40 grams of dried garlic flakes for the same period, and the third group, acting as the control group, was not given any treatment.

Findings

  • Two weeks after the horses began receiving the garlic treatments, fecal egg count reduction tests were carried out. The tests exhibited a failure of the garlic to reduce the shedding of the intestinal strongyles’ eggs, with the fresh garlic group showing a negative reduction of 11.7% and the dried garlic group showing a negative reduction of 19.4%. In other words, there was actually an increase in the number of eggs shed.
  • The tests also measured the horses’ red blood cell count throughout the period of garlic administration, finding that the numbers remained within normal ranges, thereby indicating that short-term garlic supplementation doesn’t lead to any noticeable changes in horses’ hematological profile.

Conclusion

  • Based on the findings, the study concluded that neither fresh nor dried garlic effectively reduced the shedding of eggs in horses infected with intestinal strongyles under the conditions studied. Thus, the researchers determined that the oral administration of garlic has no effect on this specific phenomenon.

Cite This Article

APA
Buono F, Pacifico L, Piantedosi D, Sgroi G, Neola B, Roncoroni C, Genovese A, Rufrano D, Veneziano V. (2018). Preliminary Observations of the Effect of Garlic on Egg Shedding in Horses Naturally Infected by Intestinal Strongyles. J Equine Vet Sci, 72, 79-83. https://doi.org/10.1016/j.jevs.2018.10.025

Publication

ISSN: 0737-0806
NlmUniqueID: 8216840
Country: United States
Language: English
Volume: 72
Pages: 79-83
PII: S0737-0806(18)30526-4

Researcher Affiliations

Buono, Francesco
  • Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy. Electronic address: francesco.buono@unina.it.
Pacifico, Laura
  • Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Piantedosi, Diego
  • Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Sgroi, Giovanni
  • Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Neola, Benedetto
  • Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, Italy.
Roncoroni, Cristina
  • Istituto Zooprofilattico Sperimentale Lazio e Toscana, Roma, Italy.
Genovese, Angelo
  • Department of Biology, University of Naples, Federico II, Naples, Italy.
Rufrano, Domenico
  • CREA, Research Centre for Animal Production and Aquaculture, Bella Muro, Potenza, Italy.
Veneziano, Vincenzo
  • Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.

MeSH Terms

  • Animals
  • Anthelmintics / therapeutic use
  • Female
  • Garlic
  • Horses
  • Italy
  • Parasite Egg Count / veterinary
  • Strongyle Infections, Equine / drug therapy

Citations

This article has been cited 5 times.
  1. Elghandour MMMY, Maggiolino A, Vázquez-Mendoza P, Alvarado-Ramírez ER, Cedillo-Monroy J, De Palo P, Salem AZM. Moringa oleifera as a Natural Alternative for the Control of Gastrointestinal Parasites in Equines: A Review. Plants (Basel) 2023 May 8;12(9).
    doi: 10.3390/plants12091921pubmed: 37176979google scholar: lookup
  2. Scala A, Tamponi C, Sanna G, Predieri G, Dessì G, Sedda G, Buono F, Cappai MG, Veneziano V, Varcasia A. Gastrointestinal Strongyles Egg Excretion in Relation to Age, Gender, and Management of Horses in Italy. Animals (Basel) 2020 Dec 3;10(12).
    doi: 10.3390/ani10122283pubmed: 33287298google scholar: lookup
  3. Arfuso F, Bazzano M, Brianti E, Gaglio G, Passantino A, Tesei B, Laus F. Nutritional Supplements Containing Cardus mariano, Eucalyptus globulus, Gentiana lutea, Urtica urens, and Mallotus philippinensis Extracts Are Effective in Reducing Egg Shedding in Dairy Jennies (Equus asinus) Naturally Infected by Cyathostomins. Front Vet Sci 2020;7:556270.
    doi: 10.3389/fvets.2020.556270pubmed: 33251253google scholar: lookup
  4. Wang T, Chen X, Yan X, Su Y, Gao W, Liu C, Wang W. Progress in serology and molecular biology of equine parasite diagnosis: sustainable control strategies. Front Vet Sci 2025;12:1663577.
    doi: 10.3389/fvets.2025.1663577pubmed: 40979365google scholar: lookup
  5. Băieş MH, Cotuţiu VD, Spînu M, Mathe A, Cozma-Petruț A, Bolboacǎ SD, Engberg RM, Collin A, Cozma V. In vivo assessment of the antiparasitic effects of Allium sativum L. and Artemisia absinthium L. against gastrointestinal parasites in swine from low-input farms. BMC Vet Res 2024 Apr 1;20(1):126.
    doi: 10.1186/s12917-024-03983-3pubmed: 38561770google scholar: lookup