Primary cardiac angiosarcoma resection combined with right coronary artery bypass grafting.
Abstract: A 41-year-old woman presented with symptoms of cardiac tamponade. Diagnosis of a primary malignant tumor in the right atrium without distant metastasis was made by echocardiography, computed tomography and coronary angiography. Aggressive surgery consisting of resection of the tumor including the right atrial wall together with the right coronary artery and sinus node was performed. This was followed by coronary artery bypass grafting with myocardial electrode implantation for reconstruction of the right atrial wall using an equine pericardium. Final diagnosis was of angiosarcoma by pathological examination. Consequently, the patient underwent additional radiotherapy and was discharged. She is currently in good health with no recurrence 1.5 years after surgery.
Publication Date: 2005-12-21 PubMed ID: 16363724DOI: 10.1007/s11748-005-0152-1Google Scholar: Lookup
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Summary
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The article details a case study where a 41-year-old woman was successfully treated for a heart angiosarcoma through a combination of surgical resection and coronary artery bypass grafting, followed by radiotherapy.
Diagnosis and Treatment Strategy
- The patient initially presented with symptoms of cardiac tamponade, a life-threatening condition where fluid accumulates in the pericardium (the sac around the heart), impeding normal heart function.
- Medical imaging techniques like echocardiography, CT scan, and coronary angiography were used to identify the existence of a primary malignant tumor in her right atrium, thankfully without any distant metastasis.
- On diagnosis, a decision was made to perform an aggressive surgical intervention. This included the resection of the tumor and the neighboring right atrial wall, along with the right coronary artery and sinus node to ensure complete tumor removal.
Surgery and Pathological Analysis
- The surgical procedure was followed by coronary artery bypass grafting (CABG), a surgery that aims to improve blood flow to the heart. Also, a myocardial electrode was implanted as a part of the procedure.
- The right atrial wall was reconstructed using an equine pericardium, a technique that involves using pericardial tissue from a horse.
- The extracted tumor was sent for pathological examination, which confirmed the diagnosis of angiosarcoma, a rare and aggressive form of cancer that occurs in the inner lining of blood vessels.
Post-Surgery Concluding Treatment and Prognosis
- Following the surgical procedure, the patient underwent radiotherapy, a common practice to ensure any possible remaining cancer cells are destroyed.
- Following this comprehensive treatment approach, she was eventually discharged and has remained healthy with no signs of recurrence for 1.5 years post the surgical intervention.
This case study illustrates a successful intervention method for treating cardiac angiosarcoma using a combination of surgical resection, CABG, and postoperative radiotherapy providing initial evidence for a possibly effective treatment protocol for similar cases in the future.
Cite This Article
APA
Ishigami N, Horiba K.
(2005).
Primary cardiac angiosarcoma resection combined with right coronary artery bypass grafting.
Jpn J Thorac Cardiovasc Surg, 53(11), 624-626.
https://doi.org/10.1007/s11748-005-0152-1 Publication
Researcher Affiliations
- Department of Cardiothoracic Surgery, Fujieda Municipal General Hospital, Fujieda, Shizuoka, Japan.
MeSH Terms
- Adult
- Coronary Angiography
- Coronary Artery Bypass / methods
- Echocardiography
- Female
- Heart Neoplasms / diagnosis
- Heart Neoplasms / radiotherapy
- Heart Neoplasms / surgery
- Hemangiosarcoma / diagnosis
- Hemangiosarcoma / radiotherapy
- Hemangiosarcoma / surgery
- Humans
- Tomography, X-Ray Computed
References
This article includes 3 references
- Herrmann MA, Shankerman RA, Edwards WD, Shub C, Schaff HV. Primary cardiac angiosarcoma: a clinicopathologic study of six cases.. J Thorac Cardiovasc Surg 1992 Apr;103(4):655-64.
- Mark RJ, Poen JC, Tran LM, Fu YS, Juillard GF. Angiosarcoma. A report of 67 patients and a review of the literature.. Cancer 1996 Jun 1;77(11):2400-6.
- McFadden PM, Ochsner JL. Atrial replacement and tricuspid valve reconstruction after angiosarcoma resection.. Ann Thorac Surg 1997 Oct;64(4):1164-6.
Citations
This article has been cited 2 times.- Yanase Y, Yamauchi A, Uehara M, Tachibana K, Muraki S, Takagi N, Higami T. Surgical resection of primary cardiac lymphoma presenting as a huge mass: report of two cases. Gen Thorac Cardiovasc Surg 2012 Aug;60(8):494-7.
- Nahal C, Borden N, Chammas M, Steen T, Faber C. Circumferential Resection of the Right Atrium to Excise Angiosarcoma. JACC Case Rep 2026 Jan 28;31(4):106538.
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