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Seasonal and photoperiod-induced changes in serum prolactin and pituitary responsiveness to thyrotropin-releasing hormone in the mare.

Abstract: Experiments were conducted in the horse mare to study the effects of photoperiod and season on serum prolactin and pituitary responsiveness to thyrotropin-releasing hormone (TRH). Increasing the photoperiod to 16 hr light:8 hr dark beginning in December (Experiment 1) and September (Experiment 2) increased serum prolactin, but the rate of increase was greater when the photoperiod treatment was initiated in September. In addition, TRH-induced prolactin secretion was found to be affected by season, in that pituitary secretion (net increase in prolactin and total prolactin secreted) was significantly greater in June compared with that of January (Experiment 3). These data suggest that in the mare, photoperiod plays an important role in controlling circulating levels of prolactin, but that in addition to photoperiod, other seasonally related factors, such as temperature, are involved in modulating the seasonal rhythm of serum prolactin.
Publication Date: 1987-01-01 PubMed ID: 3099304DOI: 10.3181/00379727-184-42455Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't
  • Research Support
  • U.S. Gov't
  • P.H.S.

Summary

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This research paper investigates how different light duration and seasons affect the serum prolactin (a hormone) and the pituitary gland’s response to thyrotropin-releasing hormone in horses, highlighting the importance of these factors in controlling prolactin levels.

Introduction and Objective

  • The research aimed to understand the influence of photoperiod (the period of time each day during which an organism receives illumination) and season on serum prolactin (a hormone that promotes milk production) and the pituitary gland’s response to the thyrotropin-releasing hormone (a hormone that stimulates the release of thyroid hormones) in mares (female horses).

Methodology

  • The experiments extended the light period to comprise 16 hours of light and 8 hours of darkness, starting in both December and September, and studied the consequent variations in serum prolactin.
  • The rate of prolactin increase was observed to be higher when the photoperiod alteration started in September.
  • The research also examined the seasonal impact on TRH-induced prolactin secretion. Specifically, the secretion from the pituitary gland was significantly greater in June compared to January.”>

Findings and Conclusion

  • The experiments demonstrated that the photoperiod significantly impacts circulating prolactin levels in mares.
  • However, it was also noted that factors other than photoperiod, such as temperature and other season-related elements, played a role in regulating serum prolactin’s seasonal rhythm.
  • The findings imply a complex interplay of environmental factors in controlling hormonal secretions and responses, emphasizing the need for further research to fully understand these mechanisms.

Cite This Article

APA
Johnson AL. (1987). Seasonal and photoperiod-induced changes in serum prolactin and pituitary responsiveness to thyrotropin-releasing hormone in the mare. Proc Soc Exp Biol Med, 184(1), 118-122. https://doi.org/10.3181/00379727-184-42455

Publication

ISSN: 0037-9727
NlmUniqueID: 7505892
Country: United States
Language: English
Volume: 184
Issue: 1
Pages: 118-122

Researcher Affiliations

Johnson, A L

    MeSH Terms

    • Animals
    • Female
    • Horses / physiology
    • Light
    • Periodicity
    • Pituitary Gland / physiology
    • Prolactin / blood
    • Seasons
    • Thyrotropin-Releasing Hormone / pharmacology

    Grant Funding

    • RR 07058-17 / NCRR NIH HHS

    Citations

    This article has been cited 1 times.
    1. Ishimaru M, Kume K, Murase H, Sato F, Matsui A, Ohmura H, Taya K. Effect of birth month on endocrine function in Thoroughbred foals born in Hokkaido, the northern part of Japan. J Vet Med Sci 2025 Jul 7;87(7):804-815.
      doi: 10.1292/jvms.25-0061pubmed: 40414721google scholar: lookup