Serological responses of equids fed Toxoplasma gondii oocysts.
Abstract: SEROLOGICAL and parasitological surveys indicate that Toxoplasma gondii infection is widely prevalent in horses (Riemann et a! 1975). To study the pathogenesis of orally-induced toxoplasmosis, 13 equids aged between Aix months and 13 years (nine ponies, three horses and one mule) were each inoculated orally with 10,000 oocysts of the GT-I strain of TRondii. The equids were killed 33 to 476 days after inoculation and their tissues were bioassaycd for T gondit (Dubey 1985). Details of inoculation, housing, clinical response and parasitological and histological findings were previously reported (Dubey 1985). This paper reports sero-logical findings.
Publication Date: 1987-07-01 PubMed ID: 3622463DOI: 10.1111/j.2042-3306.1987.tb01426.xGoogle Scholar: Lookup
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Summary
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The research article discusses a study into the impact of orally-induced toxoplasmosis in equids (horses, ponies, and mules) infected with Toxoplasma gondii, paying special attention to the serological responses observed.
Methods
- The study involved 13 equids of varying age, ranging from six months to 13 years. This sample included nine ponies, three horses, and one mule.
- Each subject was orally inoculated with 10,000 oocysts of the GT-1 strain of Toxoplasma gondii.
- The equids were euthanised between 33 to 476 days following inoculation, and their tissues were bioassayed for the presence of Toxoplasma gondii.
- Details of inoculation, housing, clinical response, and parasitological and histological findings were already reported in an earlier study.
Findings
- The study reports on the serological findings observed in the subjects following inoculation. Serological responses refer to how the body’s immune system reacts to the infection, specifically the production of antibodies.
- This focus implies that the researchers were interested in understanding more about how equids’ immune systems respond to infection with Toxoplasma gondii. Measuring these responses can help in determining the severity of the infection and evaluating treatment strategies.
Significance
- This research is important as it contributes to the broader understanding of toxoplasmosis, a disease that is prevalent among horses, often caused by consuming feed contaminated with Toxoplasma gondii.
- Understanding the serological responses in equids can help in developing more effective diagnosis, prevention, and treatment methods for toxoplasmosis in these animals.
Cite This Article
APA
Dubey JP, Desmonts G.
(1987).
Serological responses of equids fed Toxoplasma gondii oocysts.
Equine Vet J, 19(4), 337-339.
https://doi.org/10.1111/j.2042-3306.1987.tb01426.x Publication
Researcher Affiliations
MeSH Terms
- Animals
- Antibodies / analysis
- Horse Diseases / immunology
- Horse Diseases / parasitology
- Horses
- Perissodactyla / parasitology
- Toxoplasmosis, Animal / immunology
Citations
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- Boughattas S, Ayari K, Sa T, Aoun K, Bouratbine A. Survey of the parasite Toxoplasma gondii in human consumed ovine meat in Tunis City.. PLoS One 2014;9(1):e85044.
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- Lopes AP, Sousa S, Dubey JP, Ribeiro AJ, Silvestre R, Cotovio M, Schallig HD, Cardoso L, Cordeiro-da-Silva A. Prevalence of antibodies to Leishmania infantum and Toxoplasma gondii in horses from the north of Portugal.. Parasit Vectors 2013 Jun 17;6:178.
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